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    THERMOELECTRIC TEMPERATURE CONTROLLED COOLER FOR BIOMEDICAL APPLICATIONS
    3.
    发明申请
    THERMOELECTRIC TEMPERATURE CONTROLLED COOLER FOR BIOMEDICAL APPLICATIONS 审中-公开
    用于生物医学应用的热电温度控制冷却器

    公开(公告)号：WO2016160691A1

    公开(公告)日：2016-10-06

    申请号：PCT/US2016/024501

    申请日：2016-03-28

    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

    Inventor： VERGARA, Julio L. ,  PADULA, Andrew ,  RESTREPO, Lucas

    IPC: F28D1/03 ,  F28F3/12 ,  F25B39/02

    CPC classification number: A61G11/00 ,  A61F7/0053 ,  A61F7/0085 ,  A61F2007/0075 ,  A61F2007/0076 ,  A61F2007/0086 ,  A61F2007/0095 ,  A61G2210/70 ,  F25B21/02 ,  F25B2321/021 ,  F25B2321/023 ,  H01L35/30

    Abstract: A heat exchanger module (HEM) and system uses a flexible substrate with one or more open channels, to which a substrate cover is bonded, thereby forming closed channels in the flexible substrate. Thermoelectric coolers (TECs) are attached to optional thermally diffusing copper squares atop the substrate cover. An interface cover is attached to the TEC tops, with a compliant thermally conductive material opposite the TECs and ultimately in contact with a patient. A liquid is passed through the closed channels, which act as thermal references for the TECs. Current is supplied by a controller to the TECs to induce TEC cooling or heating relative to the liquid. One or more temperature sensors detect the temperature of the interface cover, which are used as inputs to the control of the TEC supply current. The HEM may be used for heating, cooling, or cycling between heating and cooling for various medical uses.

    Abstract translation: 热交换器模块（HEM）和系统使用具有一个或多个开放通道的柔性基板，衬底盖被粘合到该开口通道上，从而在柔性基板中形成闭合通道。 热电冷却器（TEC）连接到基板盖上方的可选热扩散铜方块。 接口盖连接到TEC顶部，具有与TEC相对并且最终与患者接触的柔性导热材料。 液体通过闭合通道，其作为TEC的热参考。 电流由控制器提供给TEC以相对于液体诱导TEC冷却或加热。 一个或多个温度传感器检测接口盖的温度，该温度用作TEC电源电流控制的输入。 HEM可用于加热，冷却或加热和冷却之间的循环，用于各种医疗用途。

    AUTONOMOUS TEMPERATURE CONTROL OF HEATING DEVICES FOR MEDICAL TREATMENT
    4.
    发明申请
    AUTONOMOUS TEMPERATURE CONTROL OF HEATING DEVICES FOR MEDICAL TREATMENT 审中-公开
    用于医疗治疗的加热装置的自动温度控制

    公开(公告)号：WO2016057872A1

    公开(公告)日：2016-04-14

    申请号：PCT/US2015/054842

    申请日：2015-10-09

    Applicant: THE REGENT OF THE UNIVERSITY OF CALIFORNIA ,  CALIFORNIA INSTITUTE OF TECHNOLOGY

    Inventor： SCHWARTZ, Daniel, M. ,  LEE, Choon, Woo ,  GRUBBS, Robert, H.

    IPC: A61F7/00

    CPC classification number: A61F7/007 ,  A61F7/02 ,  A61F2007/0004 ,  A61F2007/0071 ,  A61F2007/008 ,  A61F2007/0095 ,  A61F2007/0226

    Abstract: The present invention is directed to heating devices, and methods of treatment using the same, wherein the heating devices comprise (a) a polymer matrix comprising a matrix of: (i) at least one polymer; and (ii) a plurality of electrically conductive particles distributed within the polymer; and (b) two electrodes in electrical communication with the polymer matrix. The heating devices are highly portable and able to control the heating temperatures within precise limits for prolonged times without the use of any external thermostatic control device, using only low voltage batteries.

    Abstract translation: 本发明涉及加热装置及其使用方法，其中加热装置包括（a）包含基质的聚合物基体：（i）至少一种聚合物; 和（ii）分散在聚合物内的多个导电颗粒; 和（b）与聚合物基质电连通的两个电极。 加热装置是高度便携的，并且能够在不使用任何外部恒温控制装置的情况下，仅使用低电压电池来控制加热温度在延长时间的精确限度内。

    SYSTEM AND METHOD FOR THERAPEUTIC MANAGEMENT OF UNPRODUCTIVE COUGH
    5.
    发明申请
    SYSTEM AND METHOD FOR THERAPEUTIC MANAGEMENT OF UNPRODUCTIVE COUGH 审中-公开
    系统和方法治疗管理的生产性咳嗽

    公开(公告)号：WO2015127401A2

    公开(公告)日：2015-08-27

    申请号：PCT/US2015/017164

    申请日：2015-02-23

    Applicant: CIRCUIT THERAPEUTICS, INC.

    Inventor： ANDERSEN, Dan ,  THOMAS, Griffith Roger

    CPC classification number: A61F7/007 ,  A61F2007/0071 ,  A61F2007/0077 ,  A61F2007/0094 ,  A61F2007/0095 ,  A61F2007/126

    Abstract: One embodiment is directed to a system for managing unproductive cough in a patient, comprising: an applicator comprising a resistive heating element and being configured to be positioned adjacent a portion of a targeted nerve tissue for treatment; a power source configured to provide electrical current to the resistive heating element; and a current controller operatively coupled to the power source and configured to raise the temperature of the portion of the targeted nerve tissue to inhibit nerve conduction.

    Abstract translation: 一个实施例针对一种用于管理患者中的非生产性咳嗽的系统，包括：施用器，其包括电阻加热元件并且被配置为邻近用于治疗的靶向神经组织的一部分定位; 配置成向电阻加热元件提供电流的电源; 以及电流控制器，所述电流控制器可操作地耦合到所述电源并且被配置为升高所述部分目标神经组织的温度以抑制神经传导。

    THERMAL DEVICE
    6.
    发明申请
    THERMAL DEVICE 审中-公开
    热装置

    公开(公告)号：WO2015056019A1

    公开(公告)日：2015-04-23

    申请号：PCT/GB2014/053110

    申请日：2014-10-16

    Applicant: BODYCHILLZ LIMITED

    Inventor： TOCKER, Stephen McCallum ,  SIMPSON, William Howden

    IPC: A41D13/005

    CPC classification number: A61F7/03 ,  A41D13/0051 ,  A41D13/0053 ,  A41D13/1245 ,  A61F7/10 ,  A61F7/106 ,  A61F2007/0018 ,  A61F2007/0056 ,  A61F2007/0095 ,  A61F2007/0233 ,  A61F2007/0234 ,  A61F2007/0273 ,  A62B17/005

    Abstract: A thermal device comprising a garment (42A) that may be placed against at least a part of the body (10), the garment (42A) defining at least one enclosed compartment (48, 50) defined between an inner wall (65) and an outer wall (66), and an inlet (21 ) whereby liquid may be introduced into each such enclosed compartment (48, 50). Each enclosed compartment (48, 50) contains dry material (30) comprising water-soluble chemical compounds that dissolve endothermically or exothermically, and also a compressed sponge (62). There may also be an air bleed valve (64) to bleed any air out of the compartment (48, 50) when water is introduced. The device enables a patient's body to be cooled or heated in emergency, needing only addition of water, and incorporating no toxic or hazardous materials.

    Abstract translation: 一种热装置，其包括可以抵靠所述主体（10）的至少一部分放置的衣服（42A），所述衣物（42A）限定限定在内壁（65）和 外壁（66）和入口（21），由此可将液体引入每个这样封闭的隔间（48,50）中。 每个封闭隔间（48,50）含有干燥材料（30），其包含吸热或放热溶解的水溶性化合物，以及压缩海绵（62）。 当引入水时，还可以存在排气阀（64）将任何空气排出隔室（48,50）。 该装置使得患者的身体在紧急情况下被冷却或加热，仅需要添加水，并且不加入有毒或危险的物质。

    TREATMENT SYSTEMS WITH FLUID MIXING SYSTEMS AND FLUID-COOLED APPLICATORS AND METHODS OF USING THE SAME
    8.
    发明申请
    TREATMENT SYSTEMS WITH FLUID MIXING SYSTEMS AND FLUID-COOLED APPLICATORS AND METHODS OF USING THE SAME 审中-公开
    具有流体混合系统和流体冷却的涂敷器的处理系统以及使用该流体混合系统的方法

    公开(公告)号：WO2014151872A3

    公开(公告)日：2014-12-31

    申请号：PCT/US2014026596

    申请日：2014-03-13

    Applicant: ZELTIQ AESTHETICS INC

    Inventor： WEBER BRYAN J ,  COAKLEY JOSEPH ,  BAKER MARK WILLIAM ,  REEVE THOMAS BURNELL

    IPC: A61F7/00 ,  A61F7/02

    CPC classification number: A61F7/0085 ,  A61F2007/0054 ,  A61F2007/0093 ,  A61F2007/0095 ,  A61F2007/029 ,  A61F2007/0295

    Abstract: A treatment system for cooling subcutaneous lipid-rich cells in a human subject includes an applicator and a control unit. The treatment system has a cooling mode for cooling tissue and a heating mode for warming tissue. The control unit includes a circulation circuit in fluid communication with the applicator, a chiller apparatus configured to chill fluid from the applicator circulation circuit, and a heater apparatus to warmed fluid from the applicator circulation circuit. The control unit mixes the chilled fluid and/or the warmed with fluid in the applicator circulation circuit control the temperature of the fluid circulated in the applicator.

    Abstract translation: 用于冷却人类受试者中皮下富含脂质的细胞的治疗系统包括施用器和控制单元。 治疗系统具有用于冷却组织的冷却模式和用于使组织变暖的加热模式。 控制单元包括与涂抹器流体连通的循环回路，构造成冷却来自涂抹器循环回路的流体的冷却器装置，以及加热来自涂抹器循环回路的流体的加热器装置。 控制单元将施加器循环回路中的冷却流体和/或加热的流体与流体混合，以控制在施加器中循环的流体的温度。

    배액 기능을 겸비한 개두 수술 환자용 뇌 냉각 장치
    10.
    发明申请
    배액 기능을 겸비한 개두 수술 환자용 뇌 냉각 장치 审中-公开
    脑冷却装置也具有流体排放功能

    公开(公告)号：WO2013122349A1

    公开(公告)日：2013-08-22

    申请号：PCT/KR2013/000957

    申请日：2013-02-06

    Applicant: 경북대학교 산학협력단

    Inventor： 박재찬 ,  석경호 ,  한형수 ,  이동익

    IPC: A61B18/02 ,  A61M1/00 ,  A61M27/00

    CPC classification number: A61F7/12 ,  A61F7/10 ,  A61F2007/0002 ,  A61F2007/0056 ,  A61F2007/0095 ,  A61F2007/101 ,  A61F2007/126 ,  A61M27/00 ,  A61M27/002 ,  A61M2027/004

    Abstract: 본 발명의 일 실시예에 따른 뇌 냉각장치는 온도센서는 냉각유체이송관의 일단과 타단에 각각 설치되어 온도를 센싱하며, 저장탱크에는 압력측정센서가 설치되고, 온도센서와 압력측정센서에는 제어부가 연결되어 제어부는 저장탱크의 압력변화 및 온도센서에서 센싱된 온도에 따라 뇌로부터 흡열된 열량을 계산하는 것이 바람직하다. 본 발명의 일 실시예에 따른 뇌 냉각장치의 냉각유체이송관과 배액관은 일측이 절곡되어 인접한 배액관 사이가 밀착되는 것이 바람직하다. 본 발명에 따른 뇌 냉각장치는 뇌 경막 또는 절개된 뇌 경막 수술이 실시된 부위에 직접 설치하여 효과적으로 열 또는 붓기를 완화시키고 사용이 끝난 후 냉각유체를 유출입시키는 두피와 두개골을 관통한 수술구멍을 통하여 뇌 냉각장치를 제거할 수 있도록 함으로써 별도의 수술 없이 제거할 수 있는 효과가 있으며, 기화된 액체질소 등을 냉각유체로 사용함으로써 별도의 기계, 전기적 설비를 구비하지 않고 뇌를 냉각시킬 수 있는 효과가 있다. 아울러 냉각장치에 설치된 드레인 홀을 이용하여 수술부위에 고여있는 혈액 등을 배출시킬 수 있는 효과가 있다.

    Abstract translation: 根据本发明的一个实施例的脑冷却装置理想地包括：温度传感器，其分别安装在用于感测温度的冷却流体输送管的一端和另一端; 安装在储罐上的压力测量传感器; 以及控制部分，其连接到温度传感器和压力测量传感器，用于计算从储存罐中的压力变化和由温度传感器感测的温度从大脑吸收的热量。 根据本发明的脑冷却装置的冷却液输送管和放电管在一侧弯曲，使得相邻的放电管彼此紧密接触。 根据本发明的脑冷却装置直接安装在硬脑膜或在已经进行硬脑膜手术的区域上，从而有效地减轻热量或肿胀，可以通过手术孔被有效地去除，穿孔通过 头皮和颅骨，并且允许冷却液通过，而不需要额外的手术，并且可以通过使用气化液氮或类似物作为冷却流体而有效地冷却大脑而不需要单独的机械或电气设备。 此外，本发明可以通过使用设置在冷却装置上的排水孔来有效地排出收集在手术区域中的血液或类似物。

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