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    ELECTROSURGICAL BIOPSY DEVICE AND METHOD
    3.
    发明申请
    ELECTROSURGICAL BIOPSY DEVICE AND METHOD 审中-公开
    电外科生物装置和方法

    公开(公告)号：WO0016697A2

    公开(公告)日：2000-03-30

    申请号：PCT/US9921416

    申请日：1999-09-17

    Applicant: SENORX INC

    Inventor： BURBANK FRED H ,  LUBOCK PAUL ,  JONES MICHAEL L ,  QUICK RICHARD L

    IPC: A61B10/02 ,  A61B1/00 ,  A61B10/00 ,  A61B17/00 ,  A61B17/22 ,  A61B17/32 ,  A61B17/34 ,  A61B18/12 ,  A61B18/14 ,  A61B19/00

    CPC classification number: A61B10/0266 ,  A61B10/02 ,  A61B17/00491 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1487 ,  A61B18/1492 ,  A61B90/17 ,  A61B90/37 ,  A61B2010/0208 ,  A61B2017/3488 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908

    Abstract: An electrosurgical biopsy device includes a stylet and a cannula movably mounted on a base. The stylet has a shaft with a head at its distal end and a stylet ablation element extending distally from the head. The stylet shaft is disposed through the cannula for axial translation therein between withdrawn and extended positions. The cannula has an opening at its distal end and a cannula ablation element adjacent the opening. Both ablation elements are activatable with energy that ablates adjacent tissue. A translation mechanism controllably moves (a) the stylet between the withdrawn and extended positions and (b) the cannula between a proximal position and a distal position relative to the base. In use, with the stylet in the withdrawn position against the distal end of the cannula, and with the stylet ablation element activated, the stylet and the cannula are pushed through the skin and the underlying tissue until the stylet head is adjacent a targeted tissue mass. Next, the stylet is extended distally from the distal end of the cannula so that its head penetrates the tissue mass. The cannula ablation element is then activated, and the cannula is pushed through the tissue mass toward the stylet head, thereby cutting a "core" through the tissue mass that is captured as a tissue specimen within the distal end of the cannula. The cannula and the stylet are then removed from the patient's body.

    Abstract translation: 电外科活检装置包括可移动地安装在基座上的管心针和套管。 探针具有在其远端具有头部的轴和从头部向远侧延伸的探针消融元件。 探针轴穿过套管布置，用于在缩回位置和延伸位置之间的轴向平移。 套管在其远端处具有开口以及邻近开口的套管消融元件。 两种消融元件都能够消融邻近组织的能量来激活。 平移机构可控地使（a）在缩回位置和延伸位置之间的探针和（b）套管相对于基部在近侧位置和远侧位置之间移动。 在使用中，在探针处于退缩位置时抵靠套管的远端，并且在激活探针消融元件的情况下，探针和套管被推过皮肤和下面的组织，直到探针头邻近目标组织块 。 接下来，将探针从套管的远端向远侧延伸，以使其头部穿透组织块。 然后启动套管消融元件，并且将套管朝向探针头推过组织块，由此切割穿过组织块的“芯”，该组织块作为套管远端内的组织标本被捕获。 然后将套管和探针从患者身体上取下。

    TISSUE SITE MARKERS FOR IN VIVO IMAGING
    6.
    发明申请
    TISSUE SITE MARKERS FOR IN VIVO IMAGING 审中-公开
    组织网站标记在VIVO成像

    公开(公告)号：WO0241786A3

    公开(公告)日：2003-04-24

    申请号：PCT/US0143403

    申请日：2001-11-16

    Applicant: SENORX INC

    Inventor： BURBANK FRED H ,  LUBOCK PAUL ,  QUICK RICHARD L ,  LOUW FRANK ,  DE SANTIS STEPHEN A

    IPC: A61B19/00

    CPC classification number: A61B19/54 ,  A61B6/12 ,  A61B8/0833 ,  A61B90/39 ,  A61B2090/08021 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3987 ,  A61B2090/3991 ,  A61M37/0069

    Abstract: The invention is directed biopsy site markers and methods of marking a biopsy site, so that the location of the biopsy cavity is readily visible by conventional imaging methods, particularly by ultrasonic imaging. The biopsy site markers of the invention have high ultrasound reflectivity, presenting a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The several disclosed embodiments of the biopsy site marker of the invention have a high contrast of acoustic impedance as placed in a tissue site, so as to efficiently reflect and scatter ultrasonic energy, and preferably include gas-filled internal pores. The markers may have a non-uniform surface contour, such as a porous, irregular, frosted, faceted, multi-planar or lobulate surface, to enhance the acoustic signature. The markers have a characteristic form which is recognizably artificial during medical imaging.

    Abstract translation: 本发明是针对活检部位标记和标记活检部位的方法，使得活检腔的位置通过常规成像方法，特别是通过超声成像容易看到。 本发明的活检部位标记物具有高的超声反射率，从小标记物呈现出实质的声学特征，以避免在随后的成像研究中掩盖诊断组织特征，并且可以容易地与生物特征区分开来。 本发明的活检部位标记物的几个公开的实施方案具有放置在组织部位中的声阻抗的高对比度，以便有效地反射和散射超声能量，并且优选地包括气体填充的内部孔。 标记可以具有不均匀的表面轮廓，例如多孔，不规则，磨砂，刻面，多平面或小叶面，以增强声学特征。 标记具有在医学成像期间可识别人造的特征形式。

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