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    RADIOFREQUENCY APPARATUS AND METHOD FOR ACCESSING A BIOPSY SITE
    1.
    发明申请
    RADIOFREQUENCY APPARATUS AND METHOD FOR ACCESSING A BIOPSY SITE 审中-公开
    用于访问生物节点的射频设备和方法

    公开(公告)号：WO0149184A9

    公开(公告)日：2002-10-31

    申请号：PCT/US0100543

    申请日：2001-01-04

    Applicant: SENORX INC

    Inventor： BURBANK FRED ,  HOMET WILLIAM C ,  LUBOCK PAUL ,  QUICK RICHARD L ,  SHABAZ MARTIN

    IPC: A61B10/02 ,  A61B10/00 ,  A61B17/22 ,  A61B17/32 ,  A61B17/34 ,  A61B18/04 ,  A61B18/14 ,  A61B19/00 ,  A61K49/00

    CPC classification number: A61B10/0266 ,  A61B10/02 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1482 ,  A61B18/1487 ,  A61B90/37 ,  A61B90/39 ,  A61B2010/0208 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908 ,  A61B2090/3987 ,  A61K49/006 ,  A61M37/0069

    Abstract: A system for accessing a desired site within a patient's body includes a cannula defining an inner lumen that opens both forwardly (18) and into a longitudinally extending side aperture formed in the side of the cannula, near its distal end. An electrosurgical stylet slidable fits inside the inner lumen. At the distal end of the stylet is an electrosurgical electrode (28) capable of cutting tissue when at forward opening (18)and permitting advancement of the system into a patient's body. The electrode, in an expanded deployed configuration, can be wider than the maximum transverse dimension of the cannula, but it may be deflected toward the center of the stylet so that the electrode fits within the inner lumen of the cannula, permitting the stylet to be inserted and removed through the cannula. An elongate guide tube having a central axial bore which communicates with an orifice in the side of the guide tube can be inserted into the inner lumen of the cannula such that the guide tube orifice coincides with the longitudinally extending side aperture of the cannula. In use, the stylet with the cannula disposed about it is advanced into the patient's tissue, using electrosurgical cutting, until the side aperture of the cannula is disposed adjacent a desired site within the patient. The stylet can then be withdrawn from the cannula providing access through the inner lumen of the cannula to the tissue at the desired site.

    Abstract translation: 用于接近患者体内的期望部位的系统包括限定内腔的套管，所述内腔向前（18）并且进入在套管的侧部中靠近其远端处形成的纵向延伸的侧孔中。 可滑动的电外科探针适合内腔。 探针的远端是能够在向前打开（18）时切割组织并且允许系统推进到患者体内的电外科电极（28）。 处于展开展开构型的电极可以比套管的最大横向尺寸更宽，但是其可以朝向通管丝的中心偏转，使得电极装配在套管的内腔内，允许通管丝是 插入并通过套管移除。 具有与引导管侧面中的孔连通的中心轴向孔的细长引导管可以插入到套管的内腔中，使得引导管孔与套管的纵向延伸侧孔重合。 在使用中，使用电外科切割将设置在其周围的套管的探针前进到患者组织中，直到套管的侧孔邻近患者体内的期望部位设置。 随后可将管心针从套管中取出，从而提供通过套管的内腔进入到期望部位的组织的通路。

    BIOPSY DEVICE WITH INNER CUTTING MEMBER
    3.
    发明申请
    BIOPSY DEVICE WITH INNER CUTTING MEMBER 审中-公开
    具有内切刀的生物装置

    公开(公告)号：WO2004075719A3

    公开(公告)日：2007-03-01

    申请号：PCT/US2004005023

    申请日：2004-02-20

    Applicant: SENORX INC

    Inventor： QUICK RICHARD L ,  LOUW FRANK R ,  LUBOCK PAUL ,  SHABAZ MARTIN V ,  SAFABASH JASON

    IPC: A61B10/00 ,  A61B10/02 ,  A61B17/00 ,  A61B17/32 ,  A61B17/34

    CPC classification number: A61B10/0275 ,  A61B17/32002 ,  A61B17/3417 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/0046 ,  A61B2017/00473 ,  A61B2017/3405 ,  A61B2017/3454 ,  A61B2090/0811

    Abstract: The invention is directed to devices and methods for separating and collecting a tissue specimen form a patient's target site. The device includes a probe member and a penetrating distal tip and a tissue receiving aperture, and a tissue cutting member which is rotatable disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture. The longitudinal edges of the aperture are preferably sharpened to engage the cutting edges of the tissue cutting member. Vacuum may be provided in the inner lumen of the cutting member to transport the tissue therethrough. Rotation, rotational oscillation and/or longitudinal reciprocation of the tissue cutting member is effective to separate a tissue specimen from surrounding tissue. An accessing cannula having a tissue receiving aperture may be concentrically disposed within the probe member and about the tissue cutting member.

    Abstract translation: 本发明涉及用于从患者的目标部位分离和收集组织标本的装置和方法。 该装置包括探针构件和穿透远侧末端和组织接收孔，以及组织切割构件，其可旋转地设置在探针构件内，以通过孔切割被拉入装置内部的组织样本。 孔的纵向边缘优选地被锐化以接合组织切割构件的切割边缘。 可以在切割构件的内腔中设置真空以将组织输送通过其中。 组织切割构件的旋转，旋转振动和/或纵向往复运动有效地将组织标本与周围组织分开。 具有组织接收孔的进入套管可以同心地设置在探针构件内并且围绕组织切割构件。

    MRI IMAGEABLE ASSEMBLY
    5.
    发明申请
    MRI IMAGEABLE ASSEMBLY 审中-公开
    MRI成像组件

    公开(公告)号：WO2008063636A2

    公开(公告)日：2008-05-29

    申请号：PCT/US2007024249

    申请日：2007-11-20

    Applicant: SENORX INC ,  LUBOCK PAUL ,  QUICK RICHARD L ,  BROADAWAY ETHAN

    Inventor： LUBOCK PAUL ,  QUICK RICHARD L ,  BROADAWAY ETHAN

    IPC: A61B19/00

    CPC classification number: A61B17/3468 ,  A61B5/055 ,  A61B17/3498 ,  A61B90/39 ,  A61B2017/00477 ,  A61B2090/062 ,  A61B2090/3908 ,  A61B2090/3954 ,  A61B2090/3987

    Abstract: A marker delivery device is described which has an obturator with an elongated shaft, an inner lumen, a proximal end, and a substantially sealed distal end. One or more tissue markers are deployed within the inner lumen of the elongated shaft of the obturator. Preferably, the tissue marker(s) is disposed within an inner lumen of a marker delivery tube which is disposed within the inner lumen of the elongated shaft of the obturator. The marker delivery tube has an opening for discharging the tissue markers into a body (e.g. biopsy) cavity. The distal tip of the marker delivery tube is configured to penetrate the substantially sealed distal end of the obturator so that tissue markers can be delivered while the obturator is in place within the body. Preferably, the obturator includes a detectable element capable of producing a relatively significant image signature during MRI.

    Abstract translation: 描述了一种标记输送装置，其具有带有细长轴，内腔，近端和基本上密封的远端的闭孔器。 一个或多个组织标记部署在闭孔器的细长轴的内腔内。 优选地，组织标记物设置在设置在闭孔器的细长轴的内腔内的标记物输送管的内腔内。 标记物输送管具有用于将组织标记物排放到体内（例如活检）腔的开口。 标记物输送管的远端构造成穿透填塞物的基本上密封的远端，使得组织标记物可以在囊腔在体内就位的同时被输送。 优选地，闭孔器包括能够在MRI期间产生相对显着的图像特征的可检测元件。

    BIOPSY DEVICE WITH SELECTABLE TISSUE RECEIVING APERTURE ORIENTATION AND SITE ILLUMINATION
    6.
    发明申请
    BIOPSY DEVICE WITH SELECTABLE TISSUE RECEIVING APERTURE ORIENTATION AND SITE ILLUMINATION 审中-公开
    具有选择性组织的生物装置接收孔径方位和场地照明

    公开(公告)号：WO2006017400A3

    公开(公告)日：2006-05-18

    申请号：PCT/US2005027071

    申请日：2005-07-29

    Applicant: SENORX INC ,  SHABAZ MARTIN V ,  QUICK RICHARD L ,  LOUW FRANK R ,  LUBOCK PAUL ,  SAFABASH JASON H

    Inventor： SHABAZ MARTIN V ,  QUICK RICHARD L ,  LOUW FRANK R ,  LUBOCK PAUL ,  SAFABASH JASON H

    IPC: A61B10/00 ,  A61B10/02 ,  A61B17/00 ,  A61B17/32 ,  A61B17/34

    CPC classification number: A61B10/0275 ,  A61B10/0266 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/3417 ,  A61B90/30 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/00473 ,  A61B2017/00486 ,  A61B2017/3405 ,  A61B2090/3908 ,  A61B2090/3987

    Abstract: The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component (11) with an elongated tubular section (15), a penetrating distal tip (16) and a tissue receiving aperture (17) in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member (20) which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component (12) to which the probe component is releasably secured. The driver has a drive member (22,23) for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members (30) for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.

    Abstract translation: 本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。 该装置包括具有细长管状部分（15）的探针部件（11），远侧末端的管状部分的远端中的穿透远侧末端（16）和组织接收孔（17），以及组织 切割构件（20），其可滑动地设置在所述探针构件内，以通过对所述组织切割构件的内腔施加真空来切割通过所述孔被拉入所述装置的内部的组织样本。 该装置还具有驱动器部件（12），探针部件可释放地固定到该部件上。 驱动器具有用于调节管状部分的取向并因此调节其中的孔的驱动构件（22,23）和一个或多个驱动构件（30），用于移动管状区段内的组织切割构件以从组织切断组织样本 通过孔延伸到管状部分的内部。 赋予组织切割器的运动至少是纵向的，并且优选地也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

    BIOPSY DEVICE WITH APERTURE ORIENTATION AND IMPROVED TIP FIELD OF THE INVENTION
    7.
    发明申请
    BIOPSY DEVICE WITH APERTURE ORIENTATION AND IMPROVED TIP FIELD OF THE INVENTION 审中-公开
    具有孔径方向和改进尖端的生物装置发明领域

    公开(公告)号：WO2005063126A3

    公开(公告)日：2005-09-15

    申请号：PCT/US2004043021

    申请日：2004-12-20

    Applicant: SENORX INC

    Inventor： SHABAZ MARTIN V ,  QUICK RICHARD L ,  LOUW FRANK R ,  LUBOCK PAUL ,  SAFABASH JASON H

    IPC: A61B10/00 ,  A61B10/02 ,  A61B17/00 ,  A61B17/32 ,  A61B17/34 ,  A61B19/00

    CPC classification number: A61B10/0275 ,  A61B10/0283 ,  A61B17/32002 ,  A61B17/32053 ,  A61B17/3417 ,  A61B90/30 ,  A61B2010/0208 ,  A61B2010/0225 ,  A61B2017/00207 ,  A61B2017/00473 ,  A61B2017/2911 ,  A61B2017/2925 ,  A61B2017/3405 ,  A61B2090/3908 ,  A61B2090/3987

    Abstract: The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component which is releasably secured to the driver component (12). The probe component has an elongated tubular section (15), a penetrating distal tip (16) and a tissue receiving aperture (17) in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member (20) which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum (59) to the inner lumen of the tissue cutting member. The driver has drive members (22, 30, 40) for operating the elements of the probe component. The tissue penetrating distal tip preferably has a triple concave curvature shape with three curved cutting edges leading to a sharp distal point.

    Abstract translation: 本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。 该装置包括可释放地固定到驱动器部件（12）的探针部件。 探针部件具有细长的管状部分（15），远侧末端的管状部分的远端中的穿透远端（16）和组织接收孔（17），以及组织切割构件（20） 可滑动地设置在所述探针构件内，以通过将真空（59）施加到所述组织切割构件的内腔来切割通过所述孔而被拉入所述装置的内部的组织样本。 驱动器具有用于操作探针部件的元件的驱动部件（22,30,40）。 组织穿透的远侧末端优选地具有三凹曲面形状，其具有三个弯曲的切割边缘，其导致尖锐的远端点。

    SHAPEABLE ELECTROSURGICAL SCALPEL
    8.
    发明申请
    SHAPEABLE ELECTROSURGICAL SCALPEL 审中-公开
    形状稳定电位

    公开(公告)号：WO02053049A3

    公开(公告)日：2003-02-27

    申请号：PCT/US0148233

    申请日：2001-12-14

    Applicant: SENORX INC

    Inventor： QUICK RICHARD L ,  LUBOCK PAUL ,  KUSSMAN DANIEL P ,  SHABAZ MARTIN V

    IPC: A61B10/00 ,  A61B10/02 ,  A61B17/32 ,  A61B18/14

    CPC classification number: A61B17/32002 ,  A61B10/0266 ,  A61B18/14 ,  A61B18/1402 ,  A61B2018/00208 ,  A61B2018/00601 ,  A61B2018/1405 ,  A61B2018/1407 ,  A61B2018/1861

    Abstract: The invention is directed to an electrosurgical device having a shapeable elongate cutting electrode having a free distal end with an exposed length of at least 0.5 inch and secured by its proximal end to the distal end of a handle. The electrosurgical device is designed for use with a high frequency electrosurgical generator which as an output at a frequency of between about 1MHz and about 10 MHz, preferably about 3 to about 8 MHz. Preferably, the output has an essentially sinusoidal waveform with little harmonic distortion. The methods provide for the enhanced cutting of a variety of tissue including muscular, connective, glandular and fatty tissue. The device is particularly suitable in performing a breast biopsy.

    Abstract translation: 本发明涉及一种具有可成形的细长切割电极的电外科装置，其具有自由远端，其暴露长度至少为0.5英寸，并通过其近端固定到手柄的远端。 电外科设备设计用于高频电外科发生器，其作为输出在约1MHz至约10MHz之间，优选约3至约8MHz的频率下使用。 优选地，输出具有几乎没有谐波失真的基本正弦波形。 该方法提供了增强切割各种组织，包括肌肉，结缔，腺体和脂肪组织。 该装置特别适用于进行乳腺活检。

    SYSTEM AND METHOD FOR MANAGING INTERMITTENT INTERFERENCE ON IMAGING SYSTEMS
    9.
    发明申请
    SYSTEM AND METHOD FOR MANAGING INTERMITTENT INTERFERENCE ON IMAGING SYSTEMS 审中-公开
    用于管理成像系统间干扰的系统和方法

    公开(公告)号：WO0171380A3

    公开(公告)日：2002-01-31

    申请号：PCT/US0108799

    申请日：2001-03-16

    Applicant: SENORX INC

    Inventor： DABNEY JAMES H ,  QUICK RICHARD L

    IPC: A61B19/00 ,  G01S7/52 ,  G01S15/89 ,  A61B18/14

    CPC classification number: G01S7/52073 ,  A61B90/36 ,  G01S7/52026 ,  G01S7/52046 ,  G01S15/899

    Abstract: A system and method for managing, reducing, or eliminating the deleterious effects of the operation of energy emitting instruments on imaging systems. The system and method of the invention can be built into the structure of an imaging system, or can be configured to adapt to existing imaging systems. An embodiment of a system incorporating features of the invention has an interference bar detector coupled to an interference bar acquisition device which relays information regarding a bar of interference to a processor which identifies the position and velocity of the interference bar moving across an image frame or image display. Based on the position and velocity of the interference bar within the image frame, the processor then computes the necessary corrections to the gating and timing of the operation of the energy emitting instrument so as to fix the position of the interference bar at a perimeter of the image display. In another embodiment, a portion of an image frame which contains interference from the operation of an energy emitting instrument can be replaced with a corresponding portion of another image frame which is clear of interference. The invention allows for such replacement of interference scrambled portions of an image frame to occur without undue interruption of the continuous image frame generation, video stream or video display output of the imaging system.

    Abstract translation: 用于管理，减少或消除能量发射仪器对成像系统的操作的有害影响的系统和方法。 本发明的系统和方法可以内置在成像系统的结构中，或者可以被配置为适应现有的成像系统。 包含本发明的特征的系统的实施例具有耦合到干涉条获取装置的干涉条检测器，该干涉条获取装置将关于干扰条的信息中继到处理器，该处理器标识干涉条移动通过图像帧或图像的位置和速度 显示。 基于图像帧内的干涉条的位置和速度，处理器然后计算对能量发射仪器的操作的选通和定时的必要校正，以便将干涉条的位置固定在 图像显示。 在另一个实施例中，包含来自能量发射装置的操作的干扰的图像帧的一部分可以被没有干扰的另一个图像帧的相应部分所取代。 本发明允许图像帧的干扰加扰部分的这种替换发生，而不会不必要地中断成像系统的连续图像帧生成，视频流或视频显示输出。

    ELECTROSURGICAL BIOPSY DEVICE AND METHOD
    10.
    发明申请
    ELECTROSURGICAL BIOPSY DEVICE AND METHOD 审中-公开
    电外科生物装置和方法

    公开(公告)号：WO0016697A2

    公开(公告)日：2000-03-30

    申请号：PCT/US9921416

    申请日：1999-09-17

    Applicant: SENORX INC

    Inventor： BURBANK FRED H ,  LUBOCK PAUL ,  JONES MICHAEL L ,  QUICK RICHARD L

    IPC: A61B10/02 ,  A61B1/00 ,  A61B10/00 ,  A61B17/00 ,  A61B17/22 ,  A61B17/32 ,  A61B17/34 ,  A61B18/12 ,  A61B18/14 ,  A61B19/00

    CPC classification number: A61B10/0266 ,  A61B10/02 ,  A61B17/00491 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1487 ,  A61B18/1492 ,  A61B90/17 ,  A61B90/37 ,  A61B2010/0208 ,  A61B2017/3488 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908

    Abstract: An electrosurgical biopsy device includes a stylet and a cannula movably mounted on a base. The stylet has a shaft with a head at its distal end and a stylet ablation element extending distally from the head. The stylet shaft is disposed through the cannula for axial translation therein between withdrawn and extended positions. The cannula has an opening at its distal end and a cannula ablation element adjacent the opening. Both ablation elements are activatable with energy that ablates adjacent tissue. A translation mechanism controllably moves (a) the stylet between the withdrawn and extended positions and (b) the cannula between a proximal position and a distal position relative to the base. In use, with the stylet in the withdrawn position against the distal end of the cannula, and with the stylet ablation element activated, the stylet and the cannula are pushed through the skin and the underlying tissue until the stylet head is adjacent a targeted tissue mass. Next, the stylet is extended distally from the distal end of the cannula so that its head penetrates the tissue mass. The cannula ablation element is then activated, and the cannula is pushed through the tissue mass toward the stylet head, thereby cutting a "core" through the tissue mass that is captured as a tissue specimen within the distal end of the cannula. The cannula and the stylet are then removed from the patient's body.

    Abstract translation: 电外科活检装置包括可移动地安装在基座上的管心针和套管。 探针具有在其远端具有头部的轴和从头部向远侧延伸的探针消融元件。 探针轴穿过套管布置，用于在缩回位置和延伸位置之间的轴向平移。 套管在其远端处具有开口以及邻近开口的套管消融元件。 两种消融元件都能够消融邻近组织的能量来激活。 平移机构可控地使（a）在缩回位置和延伸位置之间的探针和（b）套管相对于基部在近侧位置和远侧位置之间移动。 在使用中，在探针处于退缩位置时抵靠套管的远端，并且在激活探针消融元件的情况下，探针和套管被推过皮肤和下面的组织，直到探针头邻近目标组织块 。 接下来，将探针从套管的远端向远侧延伸，以使其头部穿透组织块。 然后启动套管消融元件，并且将套管朝向探针头推过组织块，由此切割穿过组织块的“芯”，该组织块作为套管远端内的组织标本被捕获。 然后将套管和探针从患者身体上取下。

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