摘要:
A method of making a nanofluidic device is carried out by providing a thermoplastic substrate having a top surface portion, the top surface portion having at least one nanofluidic feature formed therein; providing a thermoplastic cover having a bottom surface portion, the thermoplastic cover having a glass transition temperature less than that of the substrate; optionally activating one or both of the thermoplastic substrate top surface portion and the thermoplastic cover bottom surface portion; and then thermally bonding the thermoplastic cover top surface portion to the thermoplastic cover bottom surface portion to produce the nanofluidic device.