公开(公告)号：WO2014008102A1

公开(公告)日：2014-01-09

申请号：PCT/US2013/048332

申请日：2013-06-27

Applicant: THORATEC CORPORATION

Inventor： TANNER, Adam, R. ,  KEENAN, Richard, L. ,  MESSNER, Doug, M. ,  BUTLER, Michael, R.

IPC: A61M25/09 ,  A61M25/16 ,  A61M25/088 ,  A61M1/10

CPC classification number: A61M1/1036 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1031 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M1/127 ,  Y10T29/49236

Abstract: A catheter pump is disclosed herein. The catheter pump can include a catheter assembly that comprises a drive shaft and an impeller coupled to a distal end of the drive shaft. A driven assembly can be coupled to a proximal end of the drive shaft within a driven assembly housing. The catheter pump can also include a drive system that comprises a motor and a drive magnet coupled to an output shaft of the motor. The drive system can include a drive assembly housing having at least one magnet therein. Further, a securement device can be configured to prevent disengagement of the driven assembly housing from the drive assembly housing during operation of the pump.

Abstract translation: 本文公开了一种导管泵。 导管泵可以包括导管组件，其包括驱动轴和联接到驱动轴远端的叶轮。 从动组件可以在驱动组件壳体内联接到驱动轴的近端。 导管泵还可以包括驱动系统，该驱动系统包括电动机和联接到电动机的输出轴的驱动磁体。 驱动系统可以包括其中具有至少一个磁体的驱动组件壳体。 此外，固定装置可被构造成防止在操作泵期间从动组件壳体与驱动组件壳体分离。

公开(公告)号：WO2015160943A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/025960

申请日：2015-04-15

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F. ,  FITZGERALD, Keif, M. ,  KEENAN, Richard, L. ,  NEIMAN, Veronica, J.

IPC: A61M25/095

CPC classification number: A61M1/1008 ,  A61B2090/064 ,  A61B2090/3966 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1082 ,  A61M1/1084 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/125 ,  A61M2205/13 ,  A61M2205/32 ,  A61M2205/3306 ,  A61M2205/3334 ,  A61M2205/52

Abstract: Sensors for catheter pumps are disclosed herein. The catheter pump can include a catheter assembly comprising a catheter and a cannula coupled to a distal portion of the catheter. The cannula can have a proximal port for permitting the flow of blood therethrough. The catheter assembly can include a sensor to be disposed near the proximal port. A processing unit can be programmed to process a signal detected by the sensor. The processing unit can comprise a computer-readable set of rules to evaluate the signal to determine a position of the cannula relative to an aortic valve of a patient.

Abstract translation: 本文公开了用于导管泵的传感器。 导管泵可以包括导管组件，其包括导管和联接到导管的远端部分的套管。 套管可以具有用于允许血液流过其中的近端口。 导管组件可以包括设置在近端口附近的传感器。 可以对处理单元进行编程，以处理由传感器检测到的信号。 处理单元可以包括计算机可读的一组规则，以评估信号以确定套管相对于患者的主动脉瓣的位置。

公开(公告)号：WO2014164136A1

公开(公告)日：2014-10-09

申请号：PCT/US2014/020790

申请日：2014-03-05

Applicant: THORATEC CORPORATION

Inventor： SCHENCK, Alan ,  GREEN, Michael, L. ,  FITZGERALD, Keif, M. ,  MULLER, Paul, F. ,  SULLIVAN, Joseph, P. ,  SCHUBERT, Keith ,  BRISTOL, Peter, W. ,  MILLS, Jeffrey, Paul ,  LEONARD, Paul, C. ,  KEENAN, Richard, L.

IPC: A61M1/10 ,  A61M25/01 ,  A61M31/00

CPC classification number: A61M1/122 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1086 ,  A61M1/125 ,  A61M1/127 ,  A61M1/3659 ,  A61M5/142 ,  A61M5/172

Abstract: Various embodiments of a fluid handling system are disclosed herein. For example, the fluid handling system can include a catheter assembly and a console configured to control the operation of the catheter assembly. A removable interface member can be configured to provide fluid and electrical communication between the catheter assembly and the console.

Abstract translation: 本文公开了流体处理系统的各种实施例。 例如，流体处理系统可以包括导管组件和配置成控制导管组件的操作的控制台。 可移动接口构件可以被配置为在导管组件和控制台之间提供流体和电气连通。

公开(公告)号：WO2013173240A1

公开(公告)日：2013-11-21

申请号：PCT/US2013/040799

申请日：2013-05-13

Applicant: THORATEC CORPORATION

Inventor： KEENAN, Richard, L. ,  PITZGERALD, Keif, M. ,  NEIMAN, Veronica, J. ,  YUEN, Phyllis

IPC: A61M1/10 ,  A61M25/16 ,  A61M25/10 ,  A61M5/142

CPC classification number: A61M1/10 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1017 ,  A61M1/102 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M1/127

Abstract: A catheter pump assembly is provided that includes an elongate polymeric catheter body, a cannula, and a tubular interface. The elongate polymeric catheter body has a proximal end and a distal end. The cannula has an expandable portion disposed distally of the elongate polymeric catheter body. The cannula can also have another tubular portion that is proximal to the distal portion. The tubular interface has an outer surface configured to be joined to the tubular portion of the cannula and an inner surface. The inner surface is disposed over the distal end of the elongate polymeric catheter body. The tubular interface has a plurality of transverse channels extending outward from the inner surface of the tubular interface. An outer surface of the elongate polymeric catheter body projects into the transverse channels to mechanically integrate the elongate polymeric catheter body with the tubular interface.

Abstract translation: 提供了一种导管泵组件，其包括细长的聚合物导管主体，套管和管状界面。 细长聚合物导管主体具有近端和远端。 套管具有可伸长的细长聚合物导管主体的远侧设置的可扩张部分。 套管还可以具有邻近远端部分的另一个管状部分。 管状界面具有被配置为连接到套管的管状部分和内表面的外表面。 内表面设置在细长聚合物导管主体的远端上。 管状界面具有从管状界面的内表面向外延伸的多个横向通道。 细长聚合物导管体的外表面突出到横向通道中以将细长聚合物导管主体与管状界面机械地集成。

公开(公告)号：WO2012094534A3

公开(公告)日：2012-07-12

申请号：PCT/US2012/020382

申请日：2012-01-05

Applicant: THORATEC CORPORATION ,  THE PENN STATE RESEARCH FOUNDATION ,  WALTERS, Daniel, A. ,  REPKA, William, James ,  POWELL, Kevin, J. ,  KEENAN, Richard, L. ,  WALSH, Justin, M. ,  CAMPBELL, Robert, L. ,  MCBRIDE, Mark, W.

Inventor： WALTERS, Daniel, A. ,  REPKA, William, James ,  POWELL, Kevin, J. ,  KEENAN, Richard, L. ,  WALSH, Justin, M. ,  CAMPBELL, Robert, L. ,  MCBRIDE, Mark, W.

IPC: A61M1/10 ,  A61M25/01 ,  F04C2/00

Abstract: A heart pump and a catheter assembly therefor are provided that include a flexible catheter body having a proximal end and a distal end, the catheter body having a plurality of lumens therethrough. The catheter body can be sufficiently flexible to extend from a peripheral access to a patient's heart. The catheter assembly can also include an impeller assembly having an impeller and a housing. The impeller assembly can be coupled with the flexible catheter body such that a tensile force applied to opposite ends of the catheter assembly enhances the security of the connection between the catheter body and the impeller assembly.

公开(公告)号：WO2015160979A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/026013

申请日：2015-04-15

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F. ,  FITZGERALD, Keif, M. ,  KEENAN, Richard, L.

IPC: A61M1/10

CPC classification number: A61M1/1008 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1082 ,  A61M1/1084 ,  A61M1/122 ,  A61M1/125

Abstract: A catheter pump is disclosed herein. The catheter pump cars include an elongate catheter body and an impeller assembly coupled to a distal portion of the elongate catheter body. The impeller assembly can comprise an impeller configured to rotate during operation of the catheter pump. A tube can extend through at least portions of the elongate catheter body and the impeller assembly. The tube can extend distal the impeller and can be configured to remain in the portions of the elongate catheter body and the impeller assembly during operation of the catheter pump.

Abstract translation: 本文公开了一种导管泵。 导管泵车包括细长导管主体和联接到细长导管主体的远端部分的叶轮组件。 叶轮组件可以包括构造成在导管泵操作期间旋转的叶轮。 管可以延伸穿过细长导管主体和叶轮组件的至少一部分。 管可以在叶轮的远侧延伸并且可以构造成在导管泵的操作期间保留在细长导管主体和叶轮组件的部分中。

公开(公告)号：WO2014008105A1

公开(公告)日：2014-01-09

申请号：PCT/US2013/048343

申请日：2013-06-27

Applicant: THORATEC CORPORATION

Inventor： FITZGERALD, Keif, M. ,  KEENAN, Richard, L. ,  HARRISON, William, J.

IPC: A61M1/10 ,  A61M25/088 ,  A61M25/10 ,  A61M29/00

CPC classification number: A61M1/1008 ,  A61M1/10 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1024 ,  A61M1/1029 ,  A61M1/1034 ,  A61M1/12 ,  A61M1/122 ,  A61M1/125

Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self- expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.

Abstract translation: 提供了一种导管泵，其包括可旋转的叶轮和细长插管。 细长插管具有网格，该网状物围绕叶轮设置有多个圆周部件。 细长套管具有多个轴向连接器，其在远端周向构件的近侧和近侧圆周构件的远侧之间延伸。 周向构件径向自展开。 套管被构造成使细长套管移动到护套装置中时至少在网状物的远侧区域内的破裂最小化。

公开(公告)号：WO2013173239A1

公开(公告)日：2013-11-21

申请号：PCT/US2013/040798

申请日：2013-05-13

Applicant: THORATEC CORPORATION

Inventor： KEENAN, Richard, L. ,  FITZGERALD, Keif, M.

IPC: A61M1/10 ,  A61M25/16 ,  A61M25/10 ,  A61M5/142

CPC classification number: A61M1/10 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1017 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  F04D1/00 ,  F04D25/06

Abstract: In various embodiments, a catheter pump is disclosed herein. The catheter pump can include an elongated catheter body having a distal portion including an expandable cannula having an inlet and an outlet. The expandable cannula can have a delivery profile and an operational profile larger than the delivery profile. An impeller assembly can include an impeller shaft, and an impeller body can include one or more blades. The impeller blades can draw blood into the cannula when rotated. Further, an expandable support can have a mounting portion disposed on the impeller shaft distal of the impeller body and a cannula contact portion for reducing a change in tip gap due to bending of the cannula. The cannula contact portion can be disposed distal of the mounting portion.

Abstract translation: 在各种实施例中，本文公开了导管泵。 导管泵可以包括细长的导管本体，其具有包括具有入口和出口的可扩张插管的远端部分。 可扩张套管可以具有大于输送轮廓的输送轮廓和操作轮廓。 叶轮组件可以包括叶轮轴，并且叶轮本体可以包括一个或多个叶片。 旋转时叶轮叶片可以将血液吸入套管。 此外，可膨胀支撑件可以具有设置在叶轮主体远侧的叶轮轴上的安装部分和用于减少由于套管弯曲引起的尖端间隙变化的套管接触部分。 套管接触部分可以设置在安装部分的远侧。