公开(公告)号：WO2015160990A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/026025

申请日：2015-04-15

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F.

IPC: A61M1/10

CPC classification number: A61M1/1024 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1034 ,  A61M1/1082 ,  A61M1/1084 ,  A61M1/122 ,  A61M1/125

Abstract: A catheter system for a catheter pump is disclosed. The system can include an elongate catheter body having a distal portion including an expandable cannula having an inlet and an outlet. The expandable cannula can have a delivery profile and an operational profile larger than the delivery profile. An impeller assembly can include an impeller shaft and an impeller body. A sheath can have a cannula retention zone disposed over the expandable cannula and a separation zone. The cannula retention zone can have a first configuration adapted to retain the expandable cannula in the delivery profile. The system can be adapted to separate the separation zone into a first portion and a second portion disposed across a gap. The gap can enable the elongate catheter body to pass between the first and second portion so that the sheath can be removed from the elongate catheter body.

Abstract translation: 公开了一种用于导管泵的导管系统。 该系统可以包括细长的导管主体，其具有包括具有入口和出口的可扩张插管的远端部分。 可扩张套管可以具有大于输送轮廓的输送轮廓和操作轮廓。 叶轮组件可包括叶轮轴和叶轮本体。 护套可以具有布置在可扩张插管上方的插管保持区域和分离区域。 套管保持区可以具有适于将可扩张套管保持在输送轮廓中的第一构造。 该系统可以适于将分离区分离成跨越间隙设置的第一部分和第二部分。 间隙可以使细长的导管主体在第一和第二部分之间通过，使得护套可以从细长导管主体移除。

公开(公告)号：WO2015160942A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/025959

申请日：2015-04-15

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F.

IPC: A61M1/12

CPC classification number: A61M1/1034 ,  A61M1/101 ,  A61M1/102 ,  A61M1/1024 ,  A61M1/1029 ,  A61M1/1031 ,  A61M1/1082 ,  A61M1/1084 ,  A61M1/122 ,  A61M1/125

Abstract: A catheter pump assembly is provided that includes an elongate body, an elongate flexible shaft disposed in the elongate body, and an impeller coupled with the distal end of the elongate flexible shaft. The drive system includes a drive component, a motor and a tension member. The tension member is coupled with the motor and the drive component and to cause the drive component to rotate, and thereby to cause the impeller to rotate.

Abstract translation: 提供了一种导管泵组件，其包括细长主体，设置在细长主体中的细长柔性轴和与细长柔性轴的远端联接的叶轮。 驱动系统包括驱动部件，马达和张紧部件。 张力构件与电动机和驱动部件联接并且使驱动部件旋转，从而使叶轮旋转。

公开(公告)号：WO2016028644A1

公开(公告)日：2016-02-25

申请号：PCT/US2015/045370

申请日：2015-08-14

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F.

IPC: A61M25/00 ,  A61M25/06

CPC classification number: A61M1/122 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/102 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1036 ,  A61M1/125 ,  A61M25/09 ,  A61M2025/0024 ,  A61M2025/0177 ,  A61M2025/018

Abstract: A catheter assembly can include a cannula disposed at a distal portion of the catheter assembly. The cannula can have a collapsed configuration and an expanded configuration. The cannula can be arranged to permit the flow of blood therethrough when in the expanded configuration. The catheter assembly can comprise a tip member coupled with a distal portion of the cannula. A guide feature can be configured to receive a guidewire through a guide lumen formed through the guide feature. The catheter assembly can be configured such that, when the catheter assembly is inserted into a patient with the guidewire, the guidewire passes through the guide lumen and along at least a portion of an outer surface of the catheter assembly.

Abstract translation: 导管组件可以包括设置在导管组件的远端部分处的套管。 套管可以具有收缩构型和扩张构型。 插管可以布置成当处于扩展构型时允许血液流过其中。 导管组件可以包括与插管的远侧部分联接的尖端部件。 引导特征可以被配置为通过穿过引导特征形成的引导内腔接收导丝。 导管组件可以被配置成使得当导管组件被插入患有导丝的患者时，导丝穿过导管内腔并沿着导管组件的外表面的至少一部分。

公开(公告)号：WO2014164136A1

公开(公告)日：2014-10-09

申请号：PCT/US2014/020790

申请日：2014-03-05

Applicant: THORATEC CORPORATION

Inventor： SCHENCK, Alan ,  GREEN, Michael, L. ,  FITZGERALD, Keif, M. ,  MULLER, Paul, F. ,  SULLIVAN, Joseph, P. ,  SCHUBERT, Keith ,  BRISTOL, Peter, W. ,  MILLS, Jeffrey, Paul ,  LEONARD, Paul, C. ,  KEENAN, Richard, L.

IPC: A61M1/10 ,  A61M25/01 ,  A61M31/00

CPC classification number: A61M1/122 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1086 ,  A61M1/125 ,  A61M1/127 ,  A61M1/3659 ,  A61M5/142 ,  A61M5/172

Abstract: Various embodiments of a fluid handling system are disclosed herein. For example, the fluid handling system can include a catheter assembly and a console configured to control the operation of the catheter assembly. A removable interface member can be configured to provide fluid and electrical communication between the catheter assembly and the console.

Abstract translation: 本文公开了流体处理系统的各种实施例。 例如，流体处理系统可以包括导管组件和配置成控制导管组件的操作的控制台。 可移动接口构件可以被配置为在导管组件和控制台之间提供流体和电气连通。

公开(公告)号：WO2015160943A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/025960

申请日：2015-04-15

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F. ,  FITZGERALD, Keif, M. ,  KEENAN, Richard, L. ,  NEIMAN, Veronica, J.

IPC: A61M25/095

CPC classification number: A61M1/1008 ,  A61B2090/064 ,  A61B2090/3966 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1082 ,  A61M1/1084 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/125 ,  A61M2205/13 ,  A61M2205/32 ,  A61M2205/3306 ,  A61M2205/3334 ,  A61M2205/52

Abstract: Sensors for catheter pumps are disclosed herein. The catheter pump can include a catheter assembly comprising a catheter and a cannula coupled to a distal portion of the catheter. The cannula can have a proximal port for permitting the flow of blood therethrough. The catheter assembly can include a sensor to be disposed near the proximal port. A processing unit can be programmed to process a signal detected by the sensor. The processing unit can comprise a computer-readable set of rules to evaluate the signal to determine a position of the cannula relative to an aortic valve of a patient.

Abstract translation: 本文公开了用于导管泵的传感器。 导管泵可以包括导管组件，其包括导管和联接到导管的远端部分的套管。 套管可以具有用于允许血液流过其中的近端口。 导管组件可以包括设置在近端口附近的传感器。 可以对处理单元进行编程，以处理由传感器检测到的信号。 处理单元可以包括计算机可读的一组规则，以评估信号以确定套管相对于患者的主动脉瓣的位置。

公开(公告)号：WO2015160980A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/026014

申请日：2015-04-15

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F. ,  FITZGERALD, Keif, M.

IPC: A61M1/10

CPC classification number: A61M1/1086 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1013 ,  A61M1/1017 ,  A61M1/102 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/122 ,  A61M1/125 ,  A61M2205/3334

Abstract: A heart pump is disclosed herein. The heart pump can include a cannula having one or more outlets. An impeller can be positioned in the cannula. The impeller can be configured to pump blood through the outlets along a longitudinal axis when the impeller is rotated at an operational speed. The heart pump can be configured to adjust an effective area of the outlets while the impeller is rotating or to provide relative motion between the cannula and the impeller along the longitudinal axis while the impeller is rotating.

Abstract translation: 本文公开了心脏泵。 心脏泵可以包括具有一个或多个出口的套管。 叶轮可以定位在套管中。 叶轮可以被构造成当叶轮以操作速度旋转时沿着纵轴泵送血液通过出口。 心脏泵可被配置成在叶轮旋转时调节出口的有效面积，或者当叶轮旋转时沿着纵向轴线提供插管和叶轮之间的相对运动。

公开(公告)号：WO2018017678A1

公开(公告)日：2018-01-25

申请号：PCT/US2017/042803

申请日：2017-07-19

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F. ,  FITZGERALD, Keif, M. ,  BUTLER, Michael, R. ,  JENKINS, Todd

IPC: A61M1/10 ,  A61M1/12

CPC classification number: A61M1/1034 ,  A61M1/102 ,  A61M1/125 ,  A61M1/127 ,  A61M25/0026 ,  A61M2025/0079 ,  A61M2025/1022

Abstract: A catheter pump system is disclosed. The catheter pump system can include a shaft assembly and an impeller coupled with a distal portion of the shaft assembly. A motor assembly can impart rotation on the impeller through the shaft assembly, the motor assembly comprising a motor which rotates the shaft assembly. The catheter pump system can include a fluid pathway which conveys fluid proximally during operation of the catheter pump system. A seal can be disposed between the motor assembly and the impeller. The seal can be configured to impede or prevent the fluid from the fluid pathway from entering the motor assembly at least about an outer periphery of the shaft assembly. The seal can comprise an opening through which a portion of the shaft assembly extends.

Abstract translation: 公开了一种导管泵系统。 导管泵系统可以包括轴组件和与轴组件的远侧部分联接的叶轮。 马达组件可以通过轴组件在叶轮上施加旋转，马达组件包括使轴组件旋转的马达。 导管泵系统可以包括在导管泵系统的操作期间向近侧输送流体的流体路径。 密封件可以布置在马达组件和叶轮之间。 密封件可以构造成阻止或防止来自流体路径的流体至少围绕轴组件的外周进入马达组件。 密封件可以包括一个开口，轴组件的一部分通过该开口延伸。

公开(公告)号：WO2017048733A1

公开(公告)日：2017-03-23

申请号：PCT/US2016/051553

申请日：2016-09-13

Applicant: THORATEC CORPORATION

Inventor： SCHENCK, Alan, L. ,  MULLER, Paul, F. ,  FITZGERALD, Keif, M.

IPC: A61M25/00

CPC classification number: A61M25/00 ,  A61M1/101 ,  A61M1/1034 ,  A61M1/1086 ,  A61M1/122 ,  A61M1/125 ,  A61M1/3643 ,  A61M39/00 ,  A61M39/22

Abstract: Various embodiments of a fluid handling system are disclosed herein. For example, the fluid handling system can include a catheter assembly and a console configured to control the operation of the catheter assembly. A removable interface member can be configured to provide fluid and electrical communication between the catheter assembly and the console. Additionally, a control system is disclosed for controlling operation of the fluid handling system.

Abstract translation: 本文公开了流体处理系统的各种实施例。 例如，流体处理系统可以包括导管组件和配置成控制导管组件的操作的控制台。 可移动接口构件可以被配置为在导管组件和控制台之间提供流体和电气连通。 另外，公开了用于控制流体处理系统的操作的控制系统。

公开(公告)号：WO2016118777A1

公开(公告)日：2016-07-28

申请号：PCT/US2016/014371

申请日：2016-01-21

Applicant: THORATEC CORPORATION

Inventor： TANNER, Adam, R. ,  MULLER, Paul, F. ,  SCHENCK, Alan ,  BUTLER, Michael, R. ,  JENKINS, Todd

IPC: A61M1/12

CPC classification number: A61M1/125 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1012 ,  A61M1/1013 ,  A61M1/102 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1036 ,  A61M1/122 ,  A61M25/09 ,  A61M2205/3317 ,  A61M2205/3606 ,  A61M2205/366 ,  A61M2205/3666

Abstract: A catheter pump is disclosed. The catheter pump can include an impeller and a catheter body having a lumen in which waste fluid flows proximally therethrough during operation of the catheter pump. The catheter pump can also include a drive shaft disposed inside the catheter body. A motor assembly can include a chamber. The motor assembly can include a rotor disposed in the at least a portion of the chamber, the rotor mechanically coupled with a proximal portion of the drive shaft such that rotation of the rotor causes the drive shaft to rotate, the rotor including a longitudinal rotor lumen therethrough. The motor assembly can also comprise a stator assembly disposed about the rotor. During operation of the catheter pump, the waste fluid flows from the lumen into the chamber such that at least a portion of the waste fluid flows proximally through the longitudinal rotor lumen.

Abstract translation: 公开了导管泵。 导管泵可以包括叶轮和导管本体，导管主体具有内腔，废液在导管泵的操作过程中向内流过其中。 导管泵还可以包括设置在导管主体内部的驱动轴。 马达组件可以包括腔室。 马达组件可以包括设置在腔室的至少一部分中的转子，转子与驱动轴的近端部分机械耦合，使得转子的旋转使得驱动轴旋转，转子包括纵向转子腔 穿过。 马达组件还可以包括围绕转子设置的定子组件。 在导管泵的操作期间，废液从内腔流入腔室，使得废液的至少一部分向近侧流过纵向转子腔。

公开(公告)号：WO2015160979A1

公开(公告)日：2015-10-22

申请号：PCT/US2015/026013

申请日：2015-04-15

Applicant: THORATEC CORPORATION

Inventor： MULLER, Paul, F. ,  FITZGERALD, Keif, M. ,  KEENAN, Richard, L.

IPC: A61M1/10

CPC classification number: A61M1/1008 ,  A61M1/101 ,  A61M1/1024 ,  A61M1/1034 ,  A61M1/1082 ,  A61M1/1084 ,  A61M1/122 ,  A61M1/125

Abstract: A catheter pump is disclosed herein. The catheter pump cars include an elongate catheter body and an impeller assembly coupled to a distal portion of the elongate catheter body. The impeller assembly can comprise an impeller configured to rotate during operation of the catheter pump. A tube can extend through at least portions of the elongate catheter body and the impeller assembly. The tube can extend distal the impeller and can be configured to remain in the portions of the elongate catheter body and the impeller assembly during operation of the catheter pump.

Abstract translation: 本文公开了一种导管泵。 导管泵车包括细长导管主体和联接到细长导管主体的远端部分的叶轮组件。 叶轮组件可以包括构造成在导管泵操作期间旋转的叶轮。 管可以延伸穿过细长导管主体和叶轮组件的至少一部分。 管可以在叶轮的远侧延伸并且可以构造成在导管泵的操作期间保留在细长导管主体和叶轮组件的部分中。