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    DELIVERY SYSTEM AND METHOD FOR BIFURCATED GRAFT
    2.
    发明申请
    DELIVERY SYSTEM AND METHOD FOR BIFURCATED GRAFT 审中-公开
    交付系统和方法

    公开(公告)号：WO02083038A3

    公开(公告)日：2003-04-17

    申请号：PCT/US0211522

    申请日：2002-04-11

    Applicant: TRIVASCULAR INC ,  CHOBOTOV MICHAEL V ,  GLYNN BRIAN A

    Inventor： CHOBOTOV MICHAEL V ,  GLYNN BRIAN A

    IPC: A61B20060101 ,  A61F2/06

    CPC classification number: A61F2/954 ,  A61F2/07 ,  A61F2/962 ,  A61F2002/065 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2002/9665 ,  A61F2250/0003 ,  A61F2250/0098

    Abstract: A flexible low profile delivery system (10) for delivery of an expandable intracorporeal device (11), specifically, an endovascular graft, which has at least one belt (21) circumferentially disposed about the device in a constraining configuration. The belt (21) is released by a release member (24), such as a release wire, by retracting the wire from looped ends (81) of the belt (21). Multiple belts (24, 21, 22) can be used and can be released sequentially so as to control the order of release and placement of the endovascular graft (11). An outer protective sheath (53) may be disposed about the endovascular (11) graft while in a constrained state which must first be retracted or otherwise removed prior to release of the graft (11) from a constrained state. The delivery system (10) can be configured for delivery over a guiding device (18) such as a guidewire. The delivery system can also be configured for delivery of bifurcated intracorporeal devices.

    Abstract translation: 一种用于输送可膨胀的体内器械（11）的柔性薄型输送系统（10），具体地说是一种血管内移植物，其具有围绕所述装置的约束构型周向设置的至少一个皮带（21）。 通过由带（21）的环形端（81）缩回电线，带（21）由诸如释放线的释放构件（24）释放。 可以使用多个皮带（24,21,22）并且可以顺序地释放，以便控制血管内移植物（11）的释放和放置的顺序。 外护套（53）可以在受限状态下围绕血管内（11）移植物设置，其必须首先在移植物（11）从约束状态释放之前被缩回或以其他方式被移除。 输送系统（10）可以被配置为在诸如导丝的引导装置（18）上传送。 输送系统还可以配置用于输送分叉的体内器件。

    ENDOVASCULAR GRAFT FOR ANEURYSMS INVOLVING MAJOR BRANCH VESSELS
    3.
    发明申请
    ENDOVASCULAR GRAFT FOR ANEURYSMS INVOLVING MAJOR BRANCH VESSELS 审中-公开
    用于涉及主要分支血管的动脉瘤的腔内血管移植物

    公开(公告)号：WO2014059114A3

    公开(公告)日：2014-08-28

    申请号：PCT/US2013064290

    申请日：2013-10-10

    Applicant: TRIVASCULAR INC

    Inventor： CHOBOTOV MICHAEL V

    IPC: A61F2/07 ,  A61F2/06

    CPC classification number: A61F2/07 ,  A61F2002/061 ,  A61F2002/067 ,  A61F2002/077 ,  A61F2210/0085 ,  A61F2250/0003 ,  A61F2250/0069

    Abstract: Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites include a main graft or stent-graft deployable in a main artery and a vent device or stent-graft deployable in a branch artery to maintain blood flow through the main artery and from the main artery to the branch artery. Systems and methods for treating diseased bodily lumens involving branched lumen deployment sites may also include a main graft or stent-graft deployable in the main artery, a chimney graft or stent-graft deployable in both branch artery and the main artery to the branch artery and a gutter-sealing device associated with the chimney graft to prevent flow of blood among the chimney graft, the main graft and a wall of the main artery.

    Abstract translation: 用于治疗涉及分支腔部署部位的患病身体内腔的系统和方法包括可部署在主动脉中的主要移植物或支架 - 移植物和可部署在分支动脉中的通气装置或支架 - 移植物以维持血液流过主动脉和来自 主动脉至分支动脉。 用于治疗涉及分支腔部署部位的患病身体内腔的系统和方法还可以包括可配置在主动脉中的主要移植物或支架 - 移植物，可在分支动脉和主动脉两者中分配到分支动脉的烟囱移植物或覆膜支架以及 与烟囱移植物相关联的沟槽密封装置，以防止血液在烟囱移植物，主要​​移植物和主动脉的壁之间流动。

    VIRTUAL PROTOTYPING AND TESTING FOR MEDICAL DEVICE DEVELOPMENT
    4.
    发明申请
    VIRTUAL PROTOTYPING AND TESTING FOR MEDICAL DEVICE DEVELOPMENT 审中-公开
    虚拟实验和测试用于医疗设备开发

    公开(公告)号：WO0229758A3

    公开(公告)日：2003-07-10

    申请号：PCT/US0130480

    申请日：2001-09-28

    Applicant: TRIVASCULAR INC ,  WHIRLEY ROBERT G ,  CHOBOTOV MICHAEL V

    Inventor： WHIRLEY ROBERT G ,  CHOBOTOV MICHAEL V

    IPC: A61B19/00 ,  A61B17/00 ,  A61B17/12 ,  A61F2/82 ,  G06F17/50 ,  G09B23/28 ,  G06F19/00

    CPC classification number: G06F17/50 ,  A61F2/82 ,  G06G7/48 ,  G09B23/28

    Abstract: A system and method of developing better-designed medical devices, particularly prosthesis and more particularly cardiovascular stents and endovascular grafts. The system comprises a geometry generator, a mesh generator, a stress/strain/deformation analyzer, and, optionally, a visualization tool. In one embodiment, the geometry generator receives three-dimensional volumetric data of an anatomical feature and generates a geometric model. The mesh generator then receives such geometric model of an anatomical feature or an in vitro model and a geometric model of a candidate medical device. In another embodiment, the mesh generator only receives a geometric model of the candidate medical device. Using the geometric model(s) received, the mesh generator creates or generates a mesh or a finite element model. The stress/strain/deformation analyzer then receives the mesh, and the material models and loads of that mesh. Using analysis, preferably non-linear analysis, the stress/strain/deformation analyzer determines the predicted stresses, strains, and deformations on the candidate medical device. Such stresses, strains, and deformations may optionally be simulated visually using a visualization tool.

    Abstract translation: 开发更好设计的医疗装置，特别是假体，特别是心血管支架和血管内移植物的系统和方法。 该系统包括几何生成器，网格生成器，应力/应变/变形分析器以及可选的可视化工具。 在一个实施例中，几何生成器接收解剖特征的三维体积数据并生成几何模型。 然后，网格生成器接收解剖特征或候选医疗装置的体外模型和几何模型的几何模型。 在另一个实施例中，网格生成器仅接收候选医疗设备的几何模型。 使用接收的几何模型，网格生成器创建或生成网格或有限元模型。 应力/应变/变形分析仪接收网格，以及该网格的材料模型和载荷。 使用分析，优选非线性分析，应力/应变/变形分析仪确定候选医疗设备上预测的应力，应变和变形。 可以使用可视化工具任意地模拟这种应力，应变和变形。

    SAC LINER FOR ANEURYSM REPAIR
    5.
    发明申请
    SAC LINER FOR ANEURYSM REPAIR 审中-公开
    SAC内衬修复

    公开(公告)号：WO2014110231A3

    公开(公告)日：2014-09-04

    申请号：PCT/US2014010828

    申请日：2014-01-09

    Applicant: TRIVASCULAR INC

    Inventor： CHOBOTOV MICHAEL V

    IPC: A61F2/07 ,  A61F2/06

    CPC classification number: A61F2/07 ,  A61F2/06 ,  A61F2002/067 ,  A61F2002/077 ,  A61F2230/0034 ,  A61F2250/0039

    Abstract: Systems for treating aneurysms provide additional support to an aneurysmal wall by disposing a flexible vascular liner against or in close proximity to the aneurysmal wall. A system (10) comprises a liner (18) having a liner medial wall portion (18A) which is a unitary liner wall and flexibly expansive to conform to the wall (48) of the aneurysm (42). Proximal and distal anchors (22A, 22B) may be associated with the proximal and distal liner portions. The liner inhibits failure of the aneurysmal wall. The liner may also inhibit further growth in diameter of the aneurysm. Aneurysms in single arteries or near branched arteries may be supported by a flexible vascular liner.

    Abstract translation: 用于治疗动脉瘤的系统通过将柔性血管内衬设置在靠近动脉瘤壁或靠近动脉瘤壁的位置而为动脉瘤壁提供额外的支撑。 系统（10）包括具有衬里内侧壁部分（18A）的衬套（18），所述内衬壁部分是整体衬里壁，并且柔性地膨胀以符合动脉瘤（42）的壁（48）。 近端和远端锚固件（22A，22B）可以与近端和远端衬里部分相关联。 衬垫阻止动脉瘤壁的失效。 衬垫还可以抑制动脉瘤直径的进一步增长。 单个动脉或近分支动脉中的动脉瘤可以由柔性血管内衬支撑。

    KINK RESISTANT ENDOVASCULAR GRAFT
    6.
    发明申请
    KINK RESISTANT ENDOVASCULAR GRAFT 审中-公开
    抗克隆抗体内镜片

    公开(公告)号：WO2004080338A3

    公开(公告)日：2005-03-31

    申请号：PCT/US2004006843

    申请日：2004-03-05

    Applicant: TRIVASCULAR INC ,  KARI STUART E ,  CHOBOTOV MICHAEL V

    Inventor： KARI STUART E ,  CHOBOTOV MICHAEL V

    IPC: A61F2/02 ,  A61F2/06

    CPC classification number: A61F2/06 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2002/8486 ,  A61F2250/0003

    Abstract: An intracorporeal device, such as an endovascular graft, having a tubular section with circumferential or helical radial support members. The radial support members may be inflatable channels which support the tubular structure of the graft and which are appropriately sized and longitudinally spaced to prevent or reduce kinking of the tubular structure upon bending of the tubular structure.

    Abstract translation: 体外装置，例如血管内移植物，具有带圆周或螺旋形径向支撑构件的管状部分。 径向支撑构件可以是支撑移植物的管状结构并且适当地定尺寸并且纵向间隔开的可膨胀通道，以防止或减少管状结构在管状结构弯曲时的扭结。

    DELIVERY SYSTEM AND METHOD FOR BIFURCATED GRAFT
    9.
    发明申请
    DELIVERY SYSTEM AND METHOD FOR BIFURCATED GRAFT 审中-公开
    交付系统和方法

    公开(公告)号：WO2005037076A3

    公开(公告)日：2007-07-19

    申请号：PCT/US2004034114

    申请日：2004-10-15

    Applicant: TRIVASCULAR INC ,  CHOBOTOV MICHAEL V ,  GLYNN BRIAN A

    Inventor： CHOBOTOV MICHAEL V ,  GLYNN BRIAN A

    IPC: A61B20060101 ,  A61F2/06 ,  A61F11/00

    CPC classification number: A61F2/962 ,  A61F2/07 ,  A61F2/954 ,  A61F2002/065 ,  A61F2002/9505 ,  A61F2002/9511 ,  A61F2002/9517 ,  A61F2250/0003

    Abstract: A flexible low profile delivery system for delivery of an expandable intracorporeal device, specifically, an endovascular graft, which has at least one belt circumferentially disposed about the device in a constraining configuration. The belt is released by a release member, such as a release wire, by retracting the wire from looped ends of the belt. Multiple belts can be used and can be released sequentially so as to control the order of release and placement of the endovascular graft.

    Abstract translation: 用于递送可膨胀的体内器件，特别是血管内移植物的柔性低轮廓递送系统，其具有围绕所述装置围绕约束构型的至少一个带。 带通过诸如释放线的释放构件通过将线从带的环形端缩回而释放。 可以使用多个皮带并且可以顺序地释放，以便控制血管内移植物的释放和放置的顺序。

    ENDOLUMINAL PROSTHESIS ENDOLEAK MANAGEMENT
    10.
    发明申请
    ENDOLUMINAL PROSTHESIS ENDOLEAK MANAGEMENT 审中-公开
    ENDOLAKINAL PROSTHESIS ENDOLEAK管理

    公开(公告)号：WO2005039442A3

    公开(公告)日：2005-12-01

    申请号：PCT/US2004035179

    申请日：2004-10-21

    Applicant: TRIVASCULAR INC ,  CHOBOTOV MICHAEL V ,  WHIRLEY ROBERT G

    Inventor： CHOBOTOV MICHAEL V ,  WHIRLEY ROBERT G

    IPC: A61F20060101 ,  A61F2/06 ,  A61M31/00

    CPC classification number: A61F2/07 ,  A61F2/89 ,  A61F2002/065 ,  A61F2002/072 ,  A61F2002/075 ,  A61F2002/077 ,  A61F2230/0013 ,  A61F2250/0003

    Abstract: The present invention provides methods and compositions for managing endoleaks in a perigraft space around an endovascular graft. In one embodiment, a blood flow through the endovascular graft is temporarily reduced and an embolic material is delivered into the perigraft space while the blood flow through the endovascular graft is reduced. The embolic material may comprise polyethylene glycol diacrylate, pentaerthyritol tetra 3(mercaptopropionate), and a buffer.

    Abstract translation: 本发明提供了用于管理血管内移植物周围的周壁间隙中的内漏的方法和组合物。 在一个实施例中，通过血管内移植物的血流暂时减少，并且栓塞材料被输送到周围空间中，同时通过血管内移植物的血流量减少。 栓塞材料可以包含聚乙二醇二丙烯酸酯，季戊四醇四（巯基丙酸酯）和缓冲剂。

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