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    BIOCOMPATIBLE CONDUCTIVE INKS
    1.
    发明申请
    BIOCOMPATIBLE CONDUCTIVE INKS 审中-公开
    生物导电墨水

    公开(公告)号：WO2011106434A2

    公开(公告)日：2011-09-01

    申请号：PCT/US2011025937

    申请日：2011-02-23

    Applicant: UNIV FLORIDA ,  FLORES GLEN P ,  BATICH CHRISTOPHER D

    Inventor： FLORES GLEN P ,  BATICH CHRISTOPHER D

    CPC classification number: C09D11/52 ,  C08K3/08 ,  C08K9/08 ,  C09D5/38 ,  C09D7/67 ,  C09D7/68 ,  C09D11/101 ,  C09D11/38 ,  H05K1/097

    Abstract: This invention relates to compositions and methods related to biocompatible conductive inks. In a preferred embodiment the inks are printable onto biocompatible substrates and are used in the creation of biocompatible medical devices, in general, the inks comprise a plurality of particles. In one embodiment, the particles have a particle surface and an agent on the particle surface, the agent configured to prevent the particles from agglomerating when the particles are in a solution, the agent also configured to allow adjacent particle surfaces to be in contact when the particles are not in the solution due to an opening in the agent.

    Abstract translation: 本发明涉及与生物相容性导电油墨相关的组合物和方法。 在优选实施方案中，油墨可印刷到生物相容性基材上，并用于生物相容性医疗装置的生产，通常油墨包含多个颗粒。 在一个实施方案中，颗粒在颗粒表面上具有颗粒表面和试剂，所述试剂被配置为当颗粒在溶液中时防止颗粒附聚，所述试剂还构造成允许相邻的颗粒表面在 由于试剂中的开口，颗粒不在溶液中。

    GENE DELIVERY
    3.
    发明申请
    GENE DELIVERY 审中-公开
    基因交付

    公开(公告)号：WO2006111770A3

    公开(公告)日：2007-05-18

    申请号：PCT/GB2006001477

    申请日：2006-04-21

    Applicant: UNIV KEELE ,  UNIV FLORIDA ,  DOBSON JON ,  BATICH CHRISTOPHER D

    Inventor： DOBSON JON ,  BATICH CHRISTOPHER D

    IPC: A61N2/00 ,  A61N2/02

    CPC classification number: A61N2/00 ,  A61N2/004 ,  A61N2/02

    Abstract: The present invention relates to a method of delivery of a therapeutic agent to a target cell the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.

    Abstract translation: 本发明涉及向靶细胞递送治疗剂的方法，该方法包括使用磁性装置将包含治疗剂的颗粒靶向细胞，以向所述颗粒施加磁力，以便使所述颗粒朝向所述颗粒移动 并且同时移动所述磁性装置。

    MATERIALS AND METHODS FOR IMPROVED TISSUE ENGINEERING
    5.
    发明申请
    MATERIALS AND METHODS FOR IMPROVED TISSUE ENGINEERING 审中-公开
    改进组织工程的材料与方法

    公开(公告)号：WO2006104901A3

    公开(公告)日：2007-07-05

    申请号：PCT/US2006010827

    申请日：2006-03-23

    Applicant: UNIV FLORIDA ,  TOLLON MICHAEL H ,  HAMAZAKI TAKASHI ,  WILLENBERG BRADLEY JAY ,  BATICH CHRISTOPHER D ,  TERADA NAOHIRO

    Inventor： TOLLON MICHAEL H ,  HAMAZAKI TAKASHI ,  WILLENBERG BRADLEY JAY ,  BATICH CHRISTOPHER D ,  TERADA NAOHIRO

    IPC: A61L27/56 ,  C12M3/00

    CPC classification number: A61L27/18 ,  A61L27/3804 ,  A61L27/3834 ,  A61L27/3895 ,  A61L27/56 ,  C12M25/14 ,  C08L67/04

    Abstract: The subject invention provides materials and methods for improved tissue engineering. Specifically, the current invention pertains to the identification of advantageous extracellular matrix material scaffold coatings that can be used as described herein to modulate cell seeding, attachment, culturing, proliferation, and/or differentiation to a target cell. In a further embodiment, the scaffolds of the subject invention are used to modulate stem cells. In specific embodiments, a basement membrane preparation or gelatin can be used to coat polycaprolactone (PCL) scaffolds used for seeding, attaching, culturing, proliferating, and/or differentiating cells.

    Abstract translation: 本发明提供了用于改进组织工程的材料和方法。 具体而言，本发明涉及可以如本文所述使用来调节细胞接种，附着，培养，增殖和/或分化为靶细胞的有利细胞外基质材料支架涂层的鉴定。 在另一个实施方案中，本发明的支架用于调节干细胞。 在具体实施方案中，可以使用基底膜制剂或明胶来涂覆用于接种，附着，培养，增殖和/或分化细胞的聚己内酯（PCL）支架。

    DEVICES AND METHODS FOR DISRUPTION AND REMOVAL OF LUNINAL OCCLUSIONS
    6.
    发明申请
    DEVICES AND METHODS FOR DISRUPTION AND REMOVAL OF LUNINAL OCCLUSIONS 审中-公开
    用于破坏和去除肺组织的装置和方法

    公开(公告)号：WO2004100772A2

    公开(公告)日：2004-11-25

    申请号：PCT/US2004014929

    申请日：2004-05-12

    Applicant: UNIV FLORIDA ,  SANTRA SWADESHMUKUL ,  MERICLE ROBERT A ,  BATICH CHRISTOPHER D ,  STANLEY JESSIE T ,  ESKIOGLU ERIC

    Inventor： SANTRA SWADESHMUKUL ,  MERICLE ROBERT A ,  BATICH CHRISTOPHER D ,  STANLEY JESSIE T ,  ESKIOGLU ERIC

    IPC: A61B20060101 ,  A61B17/22 ,  A61B

    CPC classification number: A61B17/320725 ,  A61B17/221 ,  A61B2017/2212

    Abstract: The subject invention pertains to an elastic sheath, device, and methods for disrupting and/or removing occlusive material from lumens, particularly biological lumens, such as the vasculature, ureter, urethra, fallopian tubes, bile duct, intestines, and the like. The subject invention provides for effective disruption and removal of occlusive material, such as a thrombus, from the body lumen with minimal risk of injury to the lumen wall. Advantageously, the invention can be used to achieve a high degree of removal while minimizing the amount of occlusive material that is released into the body lumen. The subject invention further pertains to methods for disrupting and removing occlusive material from a biological lumen. In another aspect, the present invention concerns a device useful as an in vitro model of luminal occlusion and methods for using the device to test the efficacy of devices and methods for treating luminal occlusions.

    Abstract translation: 本发明涉及一种弹性护套，装置以及用于从腔，特别是生物腔，如脉管系统，输尿管，尿道，输卵管，胆管，肠等中断和/或去除闭塞性材料的方法。 本发明提供了从体腔有效破坏和去除闭塞性材料（例如血栓），同时对管腔壁的损伤风险最小。 有利地，本发明可以用于实现高度的去除，同时最小化释放到体腔中的闭塞性材料的量。 本发明进一步涉及从生物腔破坏和去除封闭材料的方法。 在另一方面，本发明涉及可用作腔腔闭塞的体外模型的装置以及使用该装置测试装置的功效的方法和用于治疗管腔闭塞的方法的装置。

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