公开(公告)号：WO2013188973A1

公开(公告)日：2013-12-27

申请号：PCT/CA2013/050467

申请日：2013-06-18

Applicant: UNIVERSITE LAVAL

Inventor： VIENS, Jean-François ,  GRAVEL, Jean-François ,  MESSADDEQ, Younès ,  LEDEMI, Yannick ,  RIOUX, Maxime

IPC: A61B5/04 ,  A61B5/00 ,  B82Y30/00

CPC classification number: A61B1/0017 ,  A61B1/00114 ,  A61B1/015 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/0476 ,  A61B5/6847 ,  B82Y30/00 ,  C03B37/01211 ,  C03B37/026 ,  C03B37/02763 ,  C03B37/02781 ,  C03B2203/16 ,  C03B2203/34 ,  G02B6/4274 ,  G02B6/43

Abstract: An optogenetic probe, an optogenetic system, and a method for fabricating an optogenetic probe are provided. The optogenetic probe has a proximal and a distal end, and includes an elongated body made of a body glass material and extending longitudinally between the proximal and distal ends. The optogenetic probe also includes at least one optical channel, each including an optical channel glass material having a refractive index larger than a refractive index of the body glass material, so as to guide light therealong. The optogenetic probes also includes at least one electrical channel, each including an electrical channel structure having an electrical conductivity larger than the electrical conductivity of the body glass material, so as to conduct electricity therealong. The optogenetic probe further includes at least one fluidic channel, each adapted for transporting fluid therealong. Each optical, electrical and fluidic channel extends longitudinally within the elongated body.

Abstract translation: 提供了一种光发射探针，一种光遗传系统和一种制造光发射探针的方法。 光发射探针具有近端和远端，并且包括由主体玻璃材料制成并在近端和远端之间纵向延伸的细长主体。 光发射探针还包括至少一个光学通道，每个光学通道包括具有大于体玻璃材料的折射率的折射率的光学通道玻璃材料，以便沿着其引导光。 光发射探针还包括至少一个电通道，每个电通道包括电导率大于体玻璃材料的电导率的电通道结构，从而沿其导电。 光发射探针还包括至少一个流体通道，每个流体通道适于在其上输送流体。 每个光学，电气和流体通道在细长体内纵向延伸。