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公开(公告)号：WO2019099502A1
公开(公告)日：2019-05-23
申请号：PCT/US2018/061029
申请日：2018-11-14
Applicant: VERILY LIFE SCIENCES LLC
Inventor： PEPIN, Brian , WHITEHURST, Todd
CPC classification number: A61B5/4818 , A61B5/0826 , A61B5/113 , A61B5/14542 , A61B5/4836 , A61B5/7267 , A61M16/0057 , A61M16/0066 , A61M16/0069 , A61M16/024 , A61M16/06 , A61M2016/0015 , A61M2016/003 , A61M2205/3569 , A61M2205/3592 , A61M2205/50 , A61M2230/40
Abstract: Examples of systems and methods for on-demand CPAP therapy are described herein. One example method of providing on-demand CPAP therapy includes monitoring a physiological parameter of a wearer, the physiological parameter associated with sleep apnea, the wearer wearing an air mask connected to an air supply device; detecting a sleep apnea event based on the physiological parameter; and in response to detecting the sleep apnea event, activating the air supply device.
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公开(公告)号：WO2018212833A1
公开(公告)日：2018-11-22
申请号：PCT/US2018/024705
申请日：2018-03-28
Applicant: VERILY LIFE SCIENCES LLC
Inventor： PEPIN, Brian , SABESAN, Shiv , LU, Bo
Abstract: The present disclosure relates to implantable neuromodulation devices and methods of fabrication, and in particular to a thin-film electrode assemblies and methods of fabricating the thin-film electrode assembly to include a soft overmold. Particularly, aspects of the present invention are directed to a thin-film electrode assembly that includes an overmold and a supporting structure formed within a portion of the overmold. The overmold includes a first polymer and the supporting structure includes a second polymer, different from the first polymer. The thin-film electrode assembly also includes a wire formed within a portion of the supporting structure, and an electrode formed on a top surface of the supporting structure and in electrical contact with the wire. The electrode has a top surface that is raised above a top surface of the overmold by a predetermined distance.
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公开(公告)号：WO2020068722A1
公开(公告)日：2020-04-02
申请号：PCT/US2019/052556
申请日：2019-09-24
Applicant: VERILY LIFE SCIENCES LLC
Inventor： KARICHERLA, Annapurna , LU, Bo , AU, Cindy , PEPIN, Brian
IPC: A61N1/05
Abstract: Embodiments relate to an implantable device. Specifically, a device includes a flexible connection component that includes a set of conductive filaments that connect a set of electrodes (or traces connected to the electrodes) and circuitry that receives and/or transmits electronic signals from and/or to the electrodes.
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公开(公告)号：WO2018152064A1
公开(公告)日：2018-08-23
申请号：PCT/US2018/017831
申请日：2018-02-12
Applicant: VERILY LIFE SCIENCES LLC
Inventor： PEPIN, Brian , SABESAN, Shiv
IPC: A61N1/36
Abstract: The present disclosure relates to implantable neuromodulation systems and methods, and in particular to systems and methods for sensing blood-based parameter changes triggered by neural stimulation and subsequently optimizing the stimulation parameters based on feedback from the sensed blood-based parameter changes. Particularly, aspects of the present invention are directed to a method that includes delivering neural stimulation to a nerve or artery/nerve plexus based on a first set of stimulation parameters, monitoring a response to the neural stimulation that includes monitoring responses of the nerve or artery/nerve plexus and blood-based parameters of the artery, modifying the first set of the stimulation parameters based on the blood-based parameters to create a second set of stimulation parameters, and delivering the neural stimulation based on the second set of the stimulation parameters.
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公开(公告)号：WO2018223020A1
公开(公告)日：2018-12-06
申请号：PCT/US2018/035639
申请日：2018-06-01
Applicant: VERILY LIFE SCIENCES LLC
Inventor： SHAH, Kedar , SABESAN, Shiv , PEPIN, Brian , FLOYD, Jared
CPC classification number: A61N1/372 , A61B5/0031 , A61N1/05 , A61N1/0551 , A61N1/37 , A61N1/3752
Abstract: A hybrid connector for connecting a bulk conductor to a planar strand of a flexible circuit is described. The hybrid connector can include a connector body, a first connector end, and a second connector end. The first connector end can be attached to the connector body and can define a first opening having a first cross-sectional shape that corresponds to a first distal end of the strand. The second connector end can be attached to the connector body opposite the first connector end and can define a second opening having a second cross-sectional shape that corresponds to a second distal end of the bulk conductor.
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Patent Agency Ranking
公开(公告)号：WO2018071365A1
公开(公告)日：2018-04-19
申请号：PCT/US2017/055840
申请日：2017-10-10
Applicant: VERILY LIFE SCIENCES LLC
Inventor： YAO, Huanfen , PEPIN, Brian
CPC classification number: A61F13/42 , A61F13/8405 , A61F2013/421 , A61F2013/423 , A61F2013/424 , A61F2013/8479 , G01N27/048 , G01N33/4833 , G01N33/493
Abstract: A diaper sensor for detecting and differentiating feces and urine in a diaper is described. The diaper sensor may include at least one pair of conductive elements positioned within an absorbent region of the diaper. The diaper sensor may also include a transmitter and a control circuit operatively connected to the at least one pair of conductive elements and the transmitter. The diaper sensor may further include a power source operatively connected to the control circuit. The control circuit may measure the conductivity between the at least one pair of conductive elements. The control circuit may also determine whether there is poop or pee present in the diaper using the conductivity. The control circuit may also transmit via the transmitter a signal indicative of whether there is excrement or pee present in the diaper.
Abstract translation: 描述了用于检测和区分尿布中的粪便和尿液的尿布传感器。 尿布传感器可以包括位于尿布的吸收区域内的至少一对导电元件。 尿布传感器还可以包括可操作地连接到至少一对导电元件和发射器的发射器和控制电路。 尿布传感器可以进一步包括可操作地连接到控制电路的电源。 控制电路可以测量至少一对导电元件之间的导电率。 控制电路还可以利用电导率来确定尿布中是否存在粪便或小便。 控制电路还可以通过发送器发送指示尿布中是否存在排泄物或小便的信号。
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公开(公告)号：WO2018067349A1
公开(公告)日：2018-04-12
申请号：PCT/US2017/053498
申请日：2017-09-26
Applicant: VERILY LIFE SCIENCES LLC
Inventor： PEPIN, Brian
Abstract: The present disclosure relates to systems, methods, and computer-readable storage devices medication adherence systems. A container may be provided with a computing unit and display screen. The display screen may be integrated into an interior surface of the container or each compartment within the container. The display screen may display messages to a user about loading the container, the contents of the container, and/or removing contents from the container. A second display screen may also be provided on a lid of the container.
Abstract translation: 本公开涉及系统，方法和计算机可读存储设备药物依从性系统。 一个容器可以配备一个计算单元和显示屏。 显示屏可以集成到容器的内表面或容器内的每个隔室中。 显示屏幕可以向用户显示关于加载容器，容器的内容物和/或从容器移除内容物的消息。 第二个显示屏也可以设置在容器的盖子上。
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8.发明申请
公开(公告)号：WO2019036210A1
公开(公告)日：2019-02-21
申请号：PCT/US2018/045263
申请日：2018-08-03
Applicant: VERILY LIFE SCIENCES LLC
Inventor： SHAH, Kedar , SABESAN, Shiv , PEPIN, Brian
Abstract: A device includes a neural interface and a lead body. The lead body includes a bulk conductor and the neural interface includes a flexible circuit. The flexible circuit includes a microfabricated substrate and an exposed electrode. An interconnect region disposed between the electrode and the bulk conductor provides electrical connection between the electrode and the bulk conductor such that electrical signals can be communicated relative to the electrode via the bulk conductor. The interconnect region can be respectively connected to the electrode and bulk conductor by wire-bonding, welding, or other suitable connection methods.
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公开(公告)号：WO2018175482A1
公开(公告)日：2018-09-27
申请号：PCT/US2018/023416
申请日：2018-03-20
Applicant: VERILY LIFE SCIENCES LLC
Inventor： PEPIN, Brian , CONG, Peng , SHAH, Kedar , SABESAN, Shivkumar
CPC classification number: A61N1/0558 , A61N1/05 , A61N1/0556 , A61N1/08 , A61N1/36
Abstract: An electrode cuff for placement around a peripheral nerve can include one or more protrusions extending from a tissue-contacting surface of the electrode cuff. A protrusion can include one or more electrodes and can have a blunt distal end. The protrusion(s) can be driven into the nerve using a driving tool designed to apply mechanical oscillations and/or swift mechanical force to the electrode cuff. The mechanical oscillations and/or swift mechanical force can insert the blunt distal ends of the protrusions into the nerve without damaging fascicles within the nerve. During implantation, a sensor associated with the driving tool and/or the electrode cuff can provide dynamic feedback to a controller for controlling the driving tool. The sensor may detect pressure, temperature, acoustic activity, and/or electrical activity to indicate when the protrusions have pierced the epineurium, allowing the controller to cease the driving tool and thus avoid damage to the fascicles.
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公开(公告)号：WO2017218338A1
公开(公告)日：2017-12-21
申请号：PCT/US2017/036760
申请日：2017-06-09
Applicant: VERILY LIFE SCIENCES LLC
Inventor： PEPIN, Brian , WISER, Robert
CPC classification number: A61B5/6808 , A61B5/0002 , A61B5/0022 , A61B5/01 , A61B5/4261 , A61B5/486 , A61B5/4875 , A61B5/7445 , A61B2562/0271 , A61B2562/029 , A61F13/42 , A61F2013/424 , G01F1/68 , G08B21/20 , G08B25/10
Abstract: A moisture-sensitive device is provided that includes a dissolvable conductive material. Exposure of the dissolvable conductive material to urine or some oilier fluid causes the dissolvable conductive material to dissolve, increasing an effective resistance of the dissolvable conductive material. This change in resistance can be detected to determine the presence of an aqueous fluid. In response to such detection, a transmitter can then provide a wireless transmission indicative of the presence of the fluid. This moisture-sensitive device can be provided in a diaper and transmissions produced by the device can be detected using a smart phone or other device and used to indicate to a user that the diaper has been soiled.
Abstract translation: 提供了包括可溶解导电材料的湿敏装置。 将可溶解的导电材料暴露于尿或一些油性流体使得可溶解的导电材料溶解，从而增加可溶解的导电材料的有效电阻。 可以检测到这种电阻变化以确定含水流体的存在。 响应于这种检测，发射机然后可以提供指示流体存在的无线传输。 这种湿敏设备可以设置在尿布中，并且可以使用智能电话或其他设备检测由设备产生的传输并且用于向用户指示尿布已经被污染。
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