公开(公告)号：WO2022256637A2

公开(公告)日：2022-12-08

申请号：PCT/US2022/032138

申请日：2022-06-03

申请人： WEINER, David ,  BHOJNAGARWALA, Pratik ,  GARY, Ebony

发明人： WEINER, David ,  BHOJNAGARWALA, Pratik ,  GARY, Ebony

IPC分类号： A61K39/205 ,  C07K14/005 ,  A61K39/12 ,  A61K31/417

摘要： Disclosed herein is a composition comprising one or more viral antigen or a recombinant nucleic acid sequence that encodes one or more viral antigen with enhanced immunogenicity in vivo. Also disclosed herein is a method of generating an immune response in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating a viral infection in a subject using said composition and methods.