公开(公告)号：WO2019143557A1

公开(公告)日：2019-07-25

申请号：PCT/US2019/013484

申请日：2019-01-14

Applicant: PULSE BIOSCIENCES, INC.

Inventor： MOSS, Kevin ,  FOSTER, Chris ,  HINMAN, Cameron, D. ,  DANITZ, David, J. ,  UECRKER, Darrin, R.

IPC: A61N1/36 ,  A61N1/05 ,  A61N1/04

CPC classification number: A61N1/0502 ,  A61B18/1445 ,  A61B34/32 ,  A61B34/37 ,  A61B2018/1425 ,  A61B2018/1432 ,  A61N1/40

Abstract: Described herein are treatment tip apparatuses (e.g., devices, systems, etc.) including one, or more preferably a plurality, of electrodes that are protected by an electrode partition, such as an electrode housing (which may be retractable) until pressed against the tissue for deployment of the electrodes and delivery of a therapeutic treatment. In particular, these apparatuses may include a plurality of treatment electrodes (e.g., needle electrodes) and be configured for the delivery of nanosecond pulsed electric fields.

公开(公告)号：WO2015069719A1

公开(公告)日：2015-05-14

申请号：PCT/US2014/064057

申请日：2014-11-05

Applicant: ETHICON ENDO-SURGERY, INC.

Inventor： STROBL, Geoffrey S.

IPC: A61B17/29 ,  A61B18/14

CPC classification number: A61B18/1445 ,  A61B17/29 ,  A61B2017/2945 ,  A61B2018/00083 ,  A61B2018/1432 ,  A61B2018/1455

Abstract: In various embodiments, a surgical instrument is disclosed. In one embodiment, the surgical instrument comprises a handle, a shaft assembly extending distally from the handle; and an end effector coupled to a distal end of the shaft assembly. The end effector comprises a jaw assembly having a proximal end and a distal end. The jaw assembly comprises a moveable jaw member and a fixed jaw member. The moveable jaw member is pivotably moveable between an open position and a closed position with respect to the fixed jaw member. In the closed position, the jaw assembly defines a radius of curvature and a smooth taper from the proximal end to the distal end.

Abstract translation: 在各种实施例中，公开了一种外科器械。 在一个实施例中，手术器械包括手柄，从手柄向远侧延伸的轴组件; 以及联接到所述轴组件的远端的端部执行器。 末端执行器包括具有近端和远端的钳口组件。 钳口组件包括可移动钳口构件和固定钳口构件。 可移动的钳口构件可相对于固定夹爪构件在打开位置和关闭位置之间可枢转地运动。 在关闭位置，钳口组件限定曲率半径和从近端到远端的平滑锥度。

公开(公告)号：WO2015069716A1

公开(公告)日：2015-05-14

申请号：PCT/US2014/064053

申请日：2014-11-05

Applicant: ETHICON ENDO-SURGERY, INC.

Inventor： STROBL, Geoffrey, S. ,  BOUDREAUX, Chad, P.

IPC: A61B17/29 ,  A61B18/14

CPC classification number: A61B18/1445 ,  A61B17/29 ,  A61B17/3205 ,  A61B18/1206 ,  A61B2017/2945 ,  A61B2018/00083 ,  A61B2018/00708 ,  A61B2018/00916 ,  A61B2018/00922 ,  A61B2018/1432 ,  A61B2018/1455 ,  A61N1/00 ,  A61N7/00

Abstract: In one embodiment, a surgical instrument comprises a handle assembly. The handle assembly comprises a closure trigger defining an energy button hole, an energy button located within the energy button hole, and a firing trigger. A shaft assembly is coupled to the handle assembly and comprises an outer tube, a closure actuator coupled to the closure trigger, and a firing actuator operatively coupled to the firing trigger. An end effector is coupled to a distal end of the shaft assembly. The end effector comprises a jaw assembly having a proximal end and a distal end. The jaw assembly comprises a first and a second jaw member. The first and second jaw members define a longitudinal slot. The closure actuator is coupled to the first jaw member to pivotally move the first jaw member from an open position to a closed position. A cutting member is deployable within the longitudinal slot.

Abstract translation: 在一个实施例中，外科器械包括手柄组件。 手柄组件包括限定能量按钮孔的闭合触发器，位于能量按钮孔内的能量按钮和触发触发器。 轴组件联接到手柄组件，并且包括外管，联接到闭合触发器的闭合致动器以及可操作地联接到击发扳机的击发致动器。 端部执行器联接到轴组件的远端。 末端执行器包括具有近端和远端的钳口组件。 钳口组件包括第一和第二钳口构件。 第一和第二钳口构件限定纵向槽。 闭合致动器联接到第一钳口构件以将第一钳口构件从打开位置枢转地移动到关闭位置。 切割构件可在纵向槽内展开。

公开(公告)号：WO2013090848A1

公开(公告)日：2013-06-20

申请号：PCT/US2012/069945

申请日：2012-12-14

Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY ,  GNANASHANMUGAM, Swaminadhan ,  KOEHLER, Jeremy Christopher ,  SUH, Insoo ,  COE, Jonathan A.

Inventor： GNANASHANMUGAM, Swaminadhan ,  KOEHLER, Jeremy Christopher ,  SUH, Insoo ,  COE, Jonathan A.

IPC: A61M25/10 ,  A61M25/088 ,  A61M25/09

CPC classification number: A61N1/36117 ,  A61B17/00 ,  A61B18/02 ,  A61B18/04 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/1815 ,  A61B2018/0022 ,  A61B2018/00345 ,  A61B2018/00357 ,  A61B2018/00375 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/0212 ,  A61B2018/046 ,  A61B2018/143 ,  A61B2018/1432 ,  A61M25/00 ,  A61M25/0043 ,  A61M25/10 ,  A61M25/1002 ,  A61M29/00 ,  A61M29/02 ,  A61M2025/006 ,  A61N1/0551 ,  A61N2/02 ,  A61N2/06 ,  A61N5/1002 ,  A61N7/022 ,  A61N2007/003

Abstract: A method is described for decreasing activity of at least one sympathetic nerve, nerve fiber or neuron innervating at least one blood vessel in the pulmonary vasculature of a patient to ameliorate pulmonary hypertension. In one embodiment, the method may involve advancing an intravascular treatment device to a target location in a target blood vessel within the pulmonary vasculature of the patient and using the treatment device to decrease activity of at least one sympathetic nerve, nerve fiber or neuron innervating the target blood vessel at or near the target location to ameliorate pulmonary hypertension.

Abstract translation: 描述了一种用于降低至少一种交感神经，神经纤维或神经元的活动的方法，所述交感神经，神经纤维或神经元支配患者的肺血管中的至少一个血管以改善肺动脉高压。 在一个实施例中，该方法可以涉及将血管内治疗装置推进到患者的肺脉管系统内的目标血管中的目标位置，并且使用治疗装置降低至少一个交感神经，神经纤维或神经元的活动， 目标位置处或附近的目标血管，以改善肺动脉高压。

公开(公告)号：WO2011146377A8

公开(公告)日：2012-12-20

申请号：PCT/US2011036617

申请日：2011-05-16

Applicant: ETHICON ENDO SURGERY INC ,  WEIZMAN PATRICK A ,  ALDRIDGE JEFFREY L ,  BANKS RAYMOND M ,  BECKMAN ANDREW T ,  CUMMINGS JOHN F ,  DIETZ TIMOTHY G ,  FALLER CRAIG N ,  GIORDANO JAMES R ,  HARRIS JASON L ,  HUANG ZHIFAN F ,  JOHNSON GREGORY M ,  KIMBALL CORY G ,  MALAVIYA PRASANNA ,  MILLER MATTHEW C ,  MIREL AL ,  NORVELL DAVID K ,  SCHALL CHRISTOPHER J ,  SHELTON FREDERICK E IV ,  STULEN FOSTER B ,  SWAYZE JEFFREY S ,  WHITE BRADLEY E ,  WIDENHOUSE TAMARA ,  WITT DAVID A ,  BERNATH STEVE G

Inventor： WEIZMAN PATRICK A ,  ALDRIDGE JEFFREY L ,  BANKS RAYMOND M ,  BECKMAN ANDREW T ,  CUMMINGS JOHN F ,  DIETZ TIMOTHY G ,  FALLER CRAIG N ,  GIORDANO JAMES R ,  HARRIS JASON L ,  HUANG ZHIFAN F ,  JOHNSON GREGORY M ,  KIMBALL CORY G ,  MALAVIYA PRASANNA ,  MILLER MATTHEW C ,  MIREL AL ,  NORVELL DAVID K ,  SCHALL CHRISTOPHER J ,  SHELTON FREDERICK E IV ,  STULEN FOSTER B ,  SWAYZE JEFFREY S ,  WHITE BRADLEY E ,  WIDENHOUSE TAMARA ,  WITT DAVID A ,  BERNATH STEVE G

IPC: A61B18/14

CPC classification number: A61B18/1445 ,  A61B17/295 ,  A61B17/32 ,  A61B17/3209 ,  A61B18/148 ,  A61B18/1485 ,  A61B2017/003 ,  A61B2017/00738 ,  A61B2017/00867 ,  A61B2017/2926 ,  A61B2017/2933 ,  A61B2017/2934 ,  A61B2017/2945 ,  A61B2017/320044 ,  A61B2018/0063 ,  A61B2018/126 ,  A61B2018/1412 ,  A61B2018/1432 ,  A61B2018/1455 ,  A61B2018/1465

Abstract: Various forms of surgical instruments are disclosed. In various embodiments, an end effector having operable and closable jaws is attached to a distal end of an elongate shaft such that portions of the jaws are axially offset from the elongate shaft. Other jaw embodiments are coupled to an actuation arrangement that permits portions of the jaws to be moved out of axial alignment with the elongate shaft. Other jaw embodiments are configured to facilitate tissue dissection. Electrosurgical instruments are also disclosed. One embodiment employs a flexible electrode that is conformable to tissue.

Abstract translation: 公开了各种形式的外科器械。 在各种实施例中，具有可操作和可闭合的钳口的末端执行器附接到细长轴的远端，使得钳口的一部分从细长轴轴向偏移。 其它钳口实施例联接到致动装置，其允许钳口的一部分移动离开与细长轴的轴向对准。 其它钳口实施例被配置为便于组织解剖。 电外科器械也被公开。 一个实施例采用与组织一致的柔性电极。

公开(公告)号：WO2012021082A3

公开(公告)日：2012-08-09

申请号：PCT/RO2011000011

申请日：2011-03-29

Applicant: ESANU CATALIN

Inventor： ESANU CATALIN

IPC: A61B17/128 ,  A61B17/122 ,  A61B17/29

CPC classification number: A61B17/29 ,  A61B17/122 ,  A61B17/1285 ,  A61B18/1445 ,  A61B2017/292 ,  A61B2017/2931 ,  A61B2017/2946 ,  A61B2018/1432

Abstract: A surgical endoscopic instrument with detachable end tool as a clamp, a clamp retrieving device and a method for their use is provided. The instrument comprises a clamp, removably connected by a coupling to an elongated shaft, this comprising two concentric tubes, which can rotate about each other, connected to a rotating element, that is attached to a housing, inside which a push-pull rod, driven by a handle, transmits the surgeon's commands, leading to the actuating of the end tool's jaws, as well as the clamp detachment/retrieving, from/to the elongated shaft, by operating the coupling, given by the rotation of the concentric tubes about each other, thus resulting in the detachment/attachment of clamp with its jaws blocked in its given position at the time of detachment. The clamp retrieving device consisting of a grasping element, attached through an elongated shaft, consisting of concentric sheaths, to a handle, where the push of a plunger, leads to the sliding of some sheaths in relation to the other(s), and subsequent clamp seizing, clamp jaws release, and clamp retrieval from the human body.

Abstract translation: 提供了具有可拆卸终端工具作为夹具的外科内窥镜器械，夹钳取回装置及其使用方法。 所述仪器包括夹具，所述夹具通过联接件可拆卸地连接到细长轴，所述夹具包括两个同心管，所述两个同心管可以彼此相对旋转，连接到旋转元件，所述旋转元件连接到外壳上，推拉杆， 由手柄驱动传递外科医生的命令，导致终端工具的钳口的致动，以及通过操作由同心管围绕同心管旋转产生的联接而从细长轴上拆卸/取回夹具 从而导致在分离时其夹爪在其给定位置被阻挡的夹具的分离/附接。 夹具回收装置由夹持元件组成，该夹持元件通过由同心套管组成的细长轴连接到手柄上，其中推动柱塞导致一些套管相对于其他套管滑动，并且随后 夹钳卡住，夹钳释放，并从人体上取回。

公开(公告)号：WO2011146377A3

公开(公告)日：2012-01-12

申请号：PCT/US2011036617

申请日：2011-05-16

Applicant: ETHICON ENDO SURGERY INC ,  WEIZMAN PATRICK A ,  ALDRIDGE JEFFREY L ,  BANKS RAYMOND M ,  BECKMAN ANDREW T ,  CUMMINGS JOHN F ,  DIETZ TIMOTHY G ,  FALLER CRAIG N ,  GIORDANO JAMES R ,  HARRIS JASON L ,  HUANG ZHIFAN F ,  JOHNSON GREGORY M ,  KIMBALL CORY G ,  MALAVIYA PRASANNA ,  MILLER MATTHEW C ,  MIREL AL ,  NORVELL DAVID K ,  SCHALL CHRISTOPHER J ,  SHELTON FREDERICK E IV ,  STULEN FOSTER B ,  SWAYZE JEFFREY S ,  WHITE BRADLEY E ,  WIDENHOUSE TAMARA S VETRO ,  WITT DAVID A ,  BERNATH STEVE G

Inventor： WEIZMAN PATRICK A ,  ALDRIDGE JEFFREY L ,  BANKS RAYMOND M ,  BECKMAN ANDREW T ,  CUMMINGS JOHN F ,  DIETZ TIMOTHY G ,  FALLER CRAIG N ,  GIORDANO JAMES R ,  HARRIS JASON L ,  HUANG ZHIFAN F ,  JOHNSON GREGORY M ,  KIMBALL CORY G ,  MALAVIYA PRASANNA ,  MILLER MATTHEW C ,  MIREL AL ,  NORVELL DAVID K ,  SCHALL CHRISTOPHER J ,  SHELTON FREDERICK E IV ,  STULEN FOSTER B ,  SWAYZE JEFFREY S ,  WHITE BRADLEY E ,  WIDENHOUSE TAMARA S VETRO ,  WITT DAVID A ,  BERNATH STEVE G

IPC: A61B18/14

CPC classification number: A61B18/1445 ,  A61B17/295 ,  A61B17/32 ,  A61B17/3209 ,  A61B18/148 ,  A61B18/1485 ,  A61B2017/003 ,  A61B2017/00738 ,  A61B2017/00867 ,  A61B2017/2926 ,  A61B2017/2933 ,  A61B2017/2934 ,  A61B2017/2945 ,  A61B2017/320044 ,  A61B2018/0063 ,  A61B2018/126 ,  A61B2018/1412 ,  A61B2018/1432 ,  A61B2018/1455 ,  A61B2018/1465

Abstract: Various forms of surgical instruments are disclosed. In various embodiments, an end effector having operable and closable jaws is attached to a distal end of an elongate shaft such that portions of the jaws are axially offset from the elongate shaft. Other jaw embodiments are coupled to an actuation arrangement that permits portions of the jaws to be moved out of axial alignment with the elongate shaft. Other jaw embodiments are configured to facilitate tissue dissection. Electrosurgical instruments are also disclosed. One embodiment employs a flexible electrode that is conformable to tissue.

Abstract translation: 公开了各种形式的手术器械。 在各种实施例中，具有可操作和可闭合钳口的端部执行器连接到细长轴的远端，使得钳口的一部分从细长轴轴向偏移。 其他夹爪实施例联接到致动装置，该致动装置允许夹爪的一部分移出与细长轴的轴向对齐。 其他钳夹实施例被构造成便于组织解剖。 还公开了电外科手术器械。 一个实施例采用适应于组织的柔性电极。

公开(公告)号：WO2011146377A2

公开(公告)日：2011-11-24

申请号：PCT/US2011/036617

申请日：2011-05-16

Applicant: ETHICON ENDO-SURGERY, INC. ,  WEIZMAN, Patrick, A. ,  ALDRIDGE, Jeffrey, L. ,  BANKS, Raymond, M. ,  BECKMAN, Andrew, T. ,  CUMMINGS, John, F. ,  DIETZ, Timothy, G. ,  FALLER, Craig, N. ,  GIORDANO, James, R. ,  HARRIS, Jason, L. ,  HUANG, Zhifan, F. ,  JOHNSON, Gregory, M. ,  KIMBALL, Cory, G. ,  MALAVIYA, Prasanna ,  MILLER, Matthew, C. ,  MIREL, Al ,  NORVELL, David, K. ,  SCHALL, Christopher, J. ,  SHELTON, Frederick, E., IV ,  STULEN, Foster, B. ,  SWAYZE, Jeffrey, S. ,  WHITE, Bradley, E. ,  WIDENHOUSE, Tamara, S., Vetro ,  WITT, David, A. ,  BERNATH, Steve, G.

Inventor： WEIZMAN, Patrick, A. ,  ALDRIDGE, Jeffrey, L. ,  BANKS, Raymond, M. ,  BECKMAN, Andrew, T. ,  CUMMINGS, John, F. ,  DIETZ, Timothy, G. ,  FALLER, Craig, N. ,  GIORDANO, James, R. ,  HARRIS, Jason, L. ,  HUANG, Zhifan, F. ,  JOHNSON, Gregory, M. ,  KIMBALL, Cory, G. ,  MALAVIYA, Prasanna ,  MILLER, Matthew, C. ,  MIREL, Al ,  NORVELL, David, K. ,  SCHALL, Christopher, J. ,  SHELTON, Frederick, E., IV ,  STULEN, Foster, B. ,  SWAYZE, Jeffrey, S. ,  WHITE, Bradley, E. ,  WIDENHOUSE, Tamara, S., Vetro ,  WITT, David, A. ,  BERNATH, Steve, G.

IPC: A61B18/14

CPC classification number: A61B18/1445 ,  A61B17/295 ,  A61B17/32 ,  A61B17/3209 ,  A61B18/148 ,  A61B18/1485 ,  A61B2017/003 ,  A61B2017/00738 ,  A61B2017/00867 ,  A61B2017/2926 ,  A61B2017/2933 ,  A61B2017/2934 ,  A61B2017/2945 ,  A61B2017/320044 ,  A61B2018/0063 ,  A61B2018/126 ,  A61B2018/1412 ,  A61B2018/1432 ,  A61B2018/1455 ,  A61B2018/1465

Abstract: Various forms of surgical instruments are disclosed. In various embodiments, an end effector having operable and closable jaws is attached to a distal end of an elongate shaft such that portions of the jaws are axially offset from the elongate shaft. Other jaw embodiments are coupled to an actuation arrangement that permits portions of the jaws to be moved out of axial alignment with the elongate shaft. Other jaw embodiments are configured to facilitate tissue dissection. Electrosurgical instruments are also disclosed. One embodiment employs a flexible electrode that is conformable to tissue.

Abstract translation: 公开了各种形式的外科器械。 在各种实施例中，具有可操作和可闭合的钳口的末端执行器附接到细长轴的远端，使得钳口的一部分从细长轴轴向偏移。 其它钳口实施例联接到致动装置，其允许钳口的一部分移动离开与细长轴的轴向对准。 其它钳口实施例被配置为便于组织解剖。 电外科器械也被公开。 一个实施例采用与组织一致的柔性电极。

公开(公告)号：WO2011137377A1

公开(公告)日：2011-11-03

申请号：PCT/US2011/034628

申请日：2011-04-29

Applicant: DFINE, INC. ,  GERMAIN, Aaron ,  SHADDUCK, John, H. ,  TRUCKAI, Csaba

Inventor： GERMAIN, Aaron ,  SHADDUCK, John, H. ,  TRUCKAI, Csaba

IPC: A61B17/00

CPC classification number: A61B17/1671 ,  A61B17/1617 ,  A61B17/1631 ,  A61B17/1642 ,  A61B17/1644 ,  A61B17/8811 ,  A61B17/8819 ,  A61B18/1477 ,  A61B2018/00101 ,  A61B2018/00339 ,  A61B2018/00565 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00642 ,  A61B2018/00714 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/143 ,  A61B2018/1432 ,  A61B2018/1435 ,  A61B2018/1497 ,  A61B2217/007 ,  A61B2218/002 ,  A61B2218/007

Abstract: Methods and devices that displace bone or other hard tissue to create a cavity in the tissue. Where such methods and devices rely on a driving mechanism for providing moving of the device to form a profile that improves displacement of the tissue. These methods and devices also allow for creating a path or cavity in bone for insertion of bone cement or other filler to treat a fracture or other condition in the bone. The features relating to the methods and devices described herein can be applied in any region of bone or hard tissue where the tissue or bone is displaced to define a bore or cavity instead of being extracted from the body such as during a drilling or ablation procedure.

Abstract translation: 取代骨或其他硬组织以在组织中形成空腔的方法和装置。 在这种方法和装置依赖于用于提供装置的移动以形成改善组织位移的轮廓的驱动机构的情况下。 这些方法和装置还允许在骨中产生用于插入骨水泥或其它填料以治疗骨中的骨折或其他状况的路径或腔。 与本文所述的方法和装置相关的特征可以应用于骨或硬组织的任何区域，其中组织或骨被移位以限定孔或腔，而不是例如在钻孔或消融过程期间从身体提取。

公开(公告)号：WO2010009218A2

公开(公告)日：2010-01-21

申请号：PCT/US2009/050671

申请日：2009-07-15

Applicant: INTUITIVE SURGICAL, INC.

Inventor： MANZO, Scott, E. ,  BURBANK, William, A. ,  HEATON, Lisa, W. ,  GRESHAM, Richard, D.

IPC: A61B18/14 ,  A61B17/29 ,  A61B19/00

CPC classification number: A61B18/1445 ,  A61B17/32 ,  A61B34/30 ,  A61B34/71 ,  A61B2017/003 ,  A61B2017/2927 ,  A61B2017/2945 ,  A61B2018/00345 ,  A61B2018/00404 ,  A61B2018/00595 ,  A61B2018/00601 ,  A61B2018/00619 ,  A61B2018/1432 ,  A61B2018/146 ,  A61B2034/305

Abstract: An electrically energized medical instrument uses one or more drive cables to both actuate mechanical components of a wrist mechanism or an effector and to electrically energize the effector. Electrical isolation can be achieved using an insulating main tube through which drive cables extend from a backend mechanism to the effector, an insulating end cover that leaves only the desired portions of the effector exposed, and one or more seals to prevent electrically conductive liquid from entering the main tube. Component count and cost may be further reduced using a pair of pulleys that are shared by four drive cables.

Abstract translation: 电动医疗器械使用一个或多个驱动电缆来致动手腕机构或效应器的机械部件并且使效应器电通电。 电绝缘可以使用绝缘主管，驱动电缆从后端机构延伸到效应器，绝缘端盖，其仅留下被暴露的效应器的期望部分，以及一个或多个密封件，以防止导电液体进入 主管。 使用由四个驱动电缆共享的一对滑轮可以进一步减少部件数量和成本。