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    ANNULAR AUGMENTATION DEVICE FOR CARDIAC VALVE REPAIR
    1.
    发明申请
    ANNULAR AUGMENTATION DEVICE FOR CARDIAC VALVE REPAIR 审中-公开
    心脏瓣膜修复的环形增强装置

    公开(公告)号：WO2018026445A1

    公开(公告)日：2018-02-08

    申请号：PCT/US2017/038785

    申请日：2017-06-22

    Applicant: EVALVE INC.

    Inventor： WEI, Michael F. ,  ABUNASSAR, Chad J.

    IPC: A61F2/24

    CPC classification number: A61F2/246 ,  A61F2/2454 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2240/001 ,  A61F2250/0098

    Abstract: A repair device (100) for repair of regurgitant mitral valves includes a body (108) having a perimeter defining an upper side and a lower side. An annular groove (106) is disposed along a posterior section of the perimeter of the device and is configured to receive posterior rim tissue of a mitral valve annulus. First and second anchors (102, 104) extend from the body (108) in an anterior direction. The first and second anchors are configured to engage with respective commissures of the mitral valve to assist in securing the repair device in position. The repair device is structured to minimize or eliminate imparting or transmitting radially outward forces along an anterior section so as to avoid imparting forces to the septum to avoid hindering the function of the aortic valve and the left ventricular outflow tract.

    Abstract translation: 用于修复反流二尖瓣的修复装置（100）包括具有限定上侧和下侧的周边的主体（108）。 环形凹槽（106）沿着装置的周边的后部布置，并被构造成接收二尖瓣环的后边缘组织。 第一和第二锚定件（102,104）从主体（108）沿向前方向延伸。 第一和第二锚固件构造成与二尖瓣的各个连合部接合以帮助将修复装置固定就位。 修复装置被构造成最小化或消除沿前部传递或传递径向向外的力，以避免对隔膜施加力以避免妨碍主动脉瓣和左心室流出道的功能。

    POSTERIOR MITRAL VALVE LEAFLET APPROXIMATION
    2.
    发明申请
    POSTERIOR MITRAL VALVE LEAFLET APPROXIMATION 审中-公开
    后二叉阀叶片近似

    公开(公告)号：WO2017205358A1

    公开(公告)日：2017-11-30

    申请号：PCT/US2017/033971

    申请日：2017-05-23

    Applicant: EDWARDS LIFESCIENCES CORPORATION

    Inventor： STEARNS, Grant, Matthew ,  TAYLOR, David, M.

    IPC: A61F2/24 ,  A61L27/04 ,  A61B17/34

    CPC classification number: A61F2/2454 ,  A61B17/0401 ,  A61B17/0469 ,  A61B2017/00247 ,  A61B2017/00309 ,  A61B2017/0034 ,  A61B2017/00358 ,  A61B2017/00575 ,  A61B2017/00606 ,  A61B2017/00783 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0437 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61F2/2466 ,  A61F2220/0016

    Abstract: The present disclosure provides embodiments of an assembly that can be used in a method for improving coaptation of the anterior and posterior mitral valve leaflets by applying a remodeling force to the posterior leaflet. In particular embodiments, the assembly includes an elongate delivery catheter having at least one lumen and an elongate flexible tension member having first and second ends. The tension member is deployable from the delivery catheter. The assembly further includes a closure member configured to be implanted in the interatrial septum of a patient' s heart, and a deployable fastener configured to be secured on the tension member adjacent to the closure member. Once secured to the heart, tension can be applied to the tension member in a direction superiorly and anteriorly toward the interatrial septum, providing a remodeling force pulling the posterior leaflet superiorly and anteriorly to improve coaptation with the anterior leaflet.

    Abstract translation: 本公开提供了可用于通过对后小叶施加重塑力来改善前和后二尖瓣小叶的接合的方法中的组件的实施方式。 在特定实施例中，组件包括具有至少一个内腔的细长输送导管和具有第一端和第二端的细长柔性拉伸构件。 张力构件可从输送导管展开。 该组件进一步包括被配置为植入患者心脏的心房间隔膜中的闭合构件以及被配置为紧邻闭合构件固定在张紧构件上的可展开紧固件。 一旦固定在心脏上，张力可以在朝向房间隔的上方和前方的方向上施加到张力构件上，提供重塑力将后小叶向上和向前牵拉以改善与前小叶的接合。

    DEVICE FOR PLACEMENT IN THE TRICUSPID ANNULUS
    5.
    发明申请
    DEVICE FOR PLACEMENT IN THE TRICUSPID ANNULUS 审中-公开
    设备安置在TRICUSPID ANNULUS

    公开(公告)号：WO2013076724A2

    公开(公告)日：2013-05-30

    申请号：PCT/IL2012/050469

    申请日：2012-11-21

    Applicant: MOR RESEARCH APPLICATIONS LTD.

    Inventor： VATURI, Mordehay

    IPC: A61F2/24

    CPC classification number: A61F2/24 ,  A61F2/2409 ,  A61F2/2412 ,  A61F2/2454 ,  A61F2/246 ,  A61F2/2463

    Abstract: A method and a device for implantation in or near an annulus of a tricuspid valve comprising at least one blood flow control element adapted to capture a volume of blood therein. Optionally or alternatively, the blood flow control element is adapted to allow at least some volume of blood to regurgitate through the annulus during at least some part of systole. Optionally or alternatively, the device comprises a relatively rigid annulus with an arc length of less than 300 degrees. Optionally or alternatively, the relatively rigid annulus comprises a plurality of tissue fixation elements positioned along no more than 300 degrees of a circumference of the annulus, for example to avoid damaging conduction pathways between an atria and a chamber.

    Abstract translation: 一种用于植入三尖瓣环或其附近的方法和装置，所述方法和装置包括至少一个血流控制元件，所述血流控制元件适于捕获其中的一定体积的血液。 可选地或备选地，血液流量控制元件适于在至少一些收缩部分期间允许至少一定体积的血液通过瓣环返流。 可选地或备选地，该装置包括具有小于300度的弧长的相对刚性的环带。 任选地或可选地，相对刚性的环包括多个组织固定元件，所述多个组织固定元件沿环的圆周不超过300度定位，例如以避免破坏心房与腔室之间的传导通路。

    TISSUE RESTRAINING DEVICES AND METHODS OF USE
    6.
    发明申请
    TISSUE RESTRAINING DEVICES AND METHODS OF USE 审中-公开
    组织限制装置及其使用方法

    公开(公告)号：WO2012159104A1

    公开(公告)日：2012-11-22

    申请号：PCT/US2012/038781

    申请日：2012-05-21

    Applicant: PAVILION MEDICAL INNOVATIONS ,  AKLOG, Lishan ,  DEGUZMAN, Brian Justo

    Inventor： AKLOG, Lishan ,  DEGUZMAN, Brian Justo

    IPC: A61F2/24

    CPC classification number: A61F2/2454 ,  A61B17/0401 ,  A61B2017/0409 ,  A61B2017/0412 ,  A61B2017/0441 ,  A61B2017/0496 ,  A61F2/2451 ,  A61F2/2457 ,  A61F2/2466

    Abstract: Tissue restraining systems and devices as well as methods of using these devices are disclosed herein. According to aspects illustrated herein, there is provided a tissue restraining device that may include an annuloplasty member having one or more contact points along a portion of the annuloplasty member in a spaced relation to one another. The tissue restraining device may also include a second anchor for placement in a substantially opposing, spaced relation to the annuloplasty member. A restraining matrix may extend from the contact points of the annuloplasty member to the second anchor.

    Abstract translation: 本文公开了组织约束系统和装置以及使用这些装置的方法。 根据本文所示的方面，提供了一种组织约束装置，其可以包括瓣环成形术构件，所述瓣膜成形术构件具有沿着瓣膜成形术构件的一部分以彼此间隔开的一部分的一个或多个接触点。 组织限制装置还可以包括第二锚固件，用于以与瓣环成形术构件基本上相对且间隔开的关系放置。 约束矩阵可以从瓣环成形术构件的接触点延伸到第二锚固件。

    DEVICE AND METHOD FOR HEART VALVE REPAIR
    8.
    发明申请
    DEVICE AND METHOD FOR HEART VALVE REPAIR 审中-公开
    用于心脏瓣膜修复的装置和方法

    公开(公告)号：WO2012137208A1

    公开(公告)日：2012-10-11

    申请号：PCT/IL2012/050126

    申请日：2012-04-04

    Applicant: THE MEDICAL RESEARCH, INFRASTRUCTURE, AND HEALTH SERVICES FUND OF THE TEL AVIV MEDICAL CENTER ,  KUDLIK, Nachman ,  PEVNAY, Demitry

    Inventor： KUDLIK, Nachman ,  PEVNAY, Demitry

    IPC: A61F2/24 ,  A61B17/04

    CPC classification number: A61F2/2454 ,  A61B17/0401 ,  A61B2017/00349 ,  A61B2017/00557 ,  A61B2017/00862 ,  A61B2017/00867 ,  A61B2017/0417 ,  A61B2017/0464 ,  A61B2090/3912 ,  A61B2090/3925 ,  A61F2/2457 ,  A61F2/2463 ,  A61F2/2466

    Abstract: The invention provides a device (50) and system for treating a heart valve having an anchor (54, 56) and one or more sutures attached to the anchor. The anchor has an expanded deployed configuration and a low caliber undeployed configuration. A delivery in a heart includes catheter and a needle slidable in the lumen of the catheter. The distal end of the catheter is inserted through the myocardium of the heart until the catheter tip is juxtaposed to the underside of the valve leaflet to be treated. The leaflet is then pierced with tip of the needle. The needle is pushed until the anchor in its undeployed configuration passes through the needle tip and is released from the catheter. The anchor is then brought to its deployed configuration on one or both surfaces of the valve leaflet.

    Abstract translation: 本发明提供了一种用于治疗心脏瓣膜的装置（50）和系统，所述心脏瓣膜具有锚固件（54,56）和连接到锚固件的一个或多个缝合线。 锚具有扩展部署配置和低口径未部署配置。 在心脏中的输送包括导管和可在导管的内腔中滑动的针。 将导管的远端插入通过心脏的心肌直到导管尖端并置到要被治疗的瓣膜小叶的下侧。 然后将小叶用针的尖端刺穿。 推动针头，直到其未展开构型中的锚固件穿过针尖并从导管释放。 然后将锚固件置于瓣膜小叶的一个或两个表面上。

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