摘要:
Biophotonic membranes for use in the management of scars are disclosed. Said biophotonic membranes comprise a silicone phase and a surfactant phase wherein the surfactant phase comprises at least one chromophore solubilized in a surfactant. Placing such biophotonic membranes over a target tissue and illuminating with light having a wavelength that overlaps with the absorption spectra of the at least one chromophore prevents or treats scars, including post-surgical scars, hypertrophic scars and keloid scars. The at least one chromophore is preferably a xanthene dye such as an eosin.
摘要:
The present technology relates to film forming compositions comprising antimicrobial agents, as well as to methods of inhibiting bacterial growth, controlling the rate of release of an antimicrobial agent from a film forming polymer, coating a medical device, rendering the inner lumen of a medical device biofilm resistant, and treating a human or animal.
摘要:
The invention is directed to a composition comprising: a substrate polyurethane; a hydrogel forming polymer on at least one of the two faces of the polyurethane substrate; and silver nanoparticles on the at least one face comprising the hydrogel forming polymer; wherein the hydrogel polymer is covalently linked to the polyurethane substrate. The invention is also directed to a process for the preparation of the composition comprising the following steps: i. Impregnating at least one face of the substrate polyurethane with a solution comprising a reactive diolefin and the free radical initiator; ii. Extracting the polyurethane from the solution and, after drying, immerging the polyurethane in a solution containing the initiator catalyst and the hydrogel forming polymer and obtaining a polyurethane covalently bond with a hydrogel forming polymer; iii. Depositing silver salts on the polyurethane-hydrogel by immerging the polyurethane- hydrogel in a solution of the silver salt, followed by reduction with chemical or physical methods; iv. Collecting the polyurethyane-hydrogel-silver product from the solution and drying the obtained dressing in air.
摘要:
Hemostatic dressings are synergistically used in conjunction with self-assembling peptide hydrogels to promote hemostasis at a target site. Related methods, kits, and devices for hemostasis are disclosed.
摘要:
A method for making a permanently wettable material is disclosed. The method includes selecting a plurality of non-polar polymer fibers (12) wherein each fiber has a surface (16), depositing a hydrophilic polymer mixture (14) on the non-polar polymer fiber surface to form a shell. The hydrophilic polymer mixture (14) includes a cross-linkable and graftable epoxy-containing polymer, such as, poly(glycidyl methacrylate-co-ethylene glycol methacrylate) copolymer (PGMA-co-POEGMA), a high weight average molecular weight polyethylene glycol (PEG), and a surfactant. A permanently wettable material is also disclosed that includes a non-polar polymer-based web (10) having fibers (12) with a surface (16). A hydrophilic polymer mixture (14) forms a shell on the non-polar polymer fiber surface (16). The hydrophilic polymer mixture (14) includes a poly(glycidyl methacrylate-co-ethylene glycol methacrylate) copolymer (PGMA-co-POEGMA), a high weight average molecular weight polyethylene glycol (PEG), and a surfactant.
摘要:
Sealing members and methods of manufacturing the same are described. A first film layer and a second film layer each having a first side and a second side can be provided. A first adhesive can be coupled to the second side of the first film layer to form a first adhesive layer. A second adhesive can be coupled to the second side of the second film layer to form a second adhesive layer, and a third adhesive can be coupled to the first side of the second film layer to form a third adhesive layer. One or more perforations can be formed through the third adhesive layer, the second film layer, and the second adhesive layer. A first side of the third adhesive layer can be coupled to a second side of the first adhesive layer.