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    DEVICES, KITS, AND METHODS FOR DETERMINING INEFFECTIVENESS OF ANESTHETICS
    1.
    发明申请
    DEVICES, KITS, AND METHODS FOR DETERMINING INEFFECTIVENESS OF ANESTHETICS 审中-公开
    用于确定麻醉无效的装置，套件和方法

    公开(公告)号：WO2017035470A1

    公开(公告)日：2017-03-02

    申请号：PCT/US2016/048990

    申请日：2016-08-26

    Applicant: ALKALIDX, INC.

    Inventor： SEGAL, Michael, M.

    IPC: A61K49/00 ,  A61K31/00 ,  A61K31/165 ,  A61K31/167 ,  A61M19/00

    CPC classification number: A61K31/167 ,  A61K31/245 ,  A61K31/585 ,  A61K33/00 ,  A61K49/0006 ,  A61K2300/00

    Abstract: In general, the invention provides kits, devices, and methods for determining the ineffectiveness of an anesthetic, (e.g., lidocaine), using a topical approach that avoids injection. The methods typically employ the placement of aliquots of two different formulations, at least one including an anesthetic, in different locations on a subject. Further embodiments may employ a single formulation including the anesthetic.

    Abstract translation: 通常，本发明提供了使用避免注射的局部方法来确定麻醉剂（例如，利多卡因）的无效性的试剂盒，装置和方法。 方法通常采用在受试者的不同位置放置两种不同制剂的等分试样，至少一种包括麻醉剂。 其它实施方案可以使用包括麻醉剂的单一制剂。

    ALLERGENS FROM INSECTS
    5.
    发明申请
    ALLERGENS FROM INSECTS 审中-公开
    过敏原

    公开(公告)号：WO2013053641A1

    公开(公告)日：2013-04-18

    申请号：PCT/EP2012/069683

    申请日：2012-10-05

    Applicant: LABOR LAUPENECK AG ,  UNIVERSITÄT BERN

    Inventor： BIGLER, Beat ,  HEMPHILL, Andrew ,  MÜLLER, Joachim

    IPC: G01N33/68 ,  A61K39/00

    CPC classification number: A61K49/0006 ,  A61K39/35 ,  A61K2039/54 ,  A61K2039/552 ,  G01N33/6854 ,  G01N2800/24

    Abstract: The invention relates to test kits for the determination of allergic dermatitis caused by insect bites in an animal such as horses, and to compositions and methods for desensitization. It was found that a culture supernatant or a cell extract of Sf21 insect cells is suitable for reliable test kits and for compositions for desensitization.

    Abstract translation: 本发明涉及用于测定由诸如马的动物中的昆虫叮咬引起的过敏性皮炎的测试试剂盒，以及用于脱敏作用的组合物和方法。 发现Sf21昆虫细胞的培养上清液或细胞提取物适用于可靠的测试试剂盒和用于脱敏的组合物。

    METHOD AND KIT FOR QUANTIFYING RISK PREDICTOR
    7.
    发明申请
    METHOD AND KIT FOR QUANTIFYING RISK PREDICTOR 审中-公开
    用于定量风险预测的方法和工具包

    公开(公告)号：WO2011079864A1

    公开(公告)日：2011-07-07

    申请号：PCT/EP2009/068018

    申请日：2009-12-30

    Applicant: DENTOSYSTEM SCANDINAVIA AB ,  LINDSKOG, Sven

    Inventor： LINDSKOG, Sven

    IPC: A61B5/103 ,  A61B10/00 ,  A61K49/00 ,  G06F19/00

    CPC classification number: A61B5/411 ,  A61B5/441 ,  A61B5/447 ,  A61B10/0035 ,  A61K49/0006

    Abstract: A method and a kit for quantification of at least one predictor promoting at least one multifactorial disease, intended for use in assessment of the risk for developing or progression of the at least one multifactorial disease for a subject are disclosed. The kit comprises a plurality of reservoir units (320), each reservoir unit (320) being arranged to releasably retain a skin irritation agent adapted to provoke an unspecific inflammatory response of skin. The kit comprises an estimation unit adapted to estimate a quantification of the at least one predictor on basis of an assessment of the at least one predictor performed by a user on basis of an assessment of the degree of severity of the inflammatory response to the skin irritation agent at each of a plurality of skin sites according to a predetermined inflammatory response criteria performed by the user and relative impact of the at least one predictor on the progress of the at least one multifactorial disease.

    Abstract translation: 公开了一种用于量化至少一种预测因子的方法和试剂盒，所述至少一种预测因子促进至少一种多因素疾病，其用于评估用于受试者的至少一种多因素疾病的发展或进展的风险。 套件包括多个储存器单元（320），每个储存器单元（320）布置成可释放地保持适于引发皮肤的非特异性炎症反应的皮肤刺激剂。 所述试剂盒包括估计单元，所述估计单元适于基于对使用者进行的所述至少一个预测因子的评估，基于对所述皮肤刺激的炎症反应的严重程度的评估来估计所述至少一个预测因子的定量 根据由用户执行的预定炎症反应标准和多个皮肤部位中的每一个的药剂，所述至少一个预测因子对所述至少一种多因素疾病的进展的相对影响。

    VERIFIABLE HAND CLEANSING FORMULATION AND METHOD
    9.
    发明申请
    VERIFIABLE HAND CLEANSING FORMULATION AND METHOD 审中-公开
    可检测手套清洗配方及方法

    公开(公告)号：WO2008118143A2

    公开(公告)日：2008-10-02

    申请号：PCT/US2007022843

    申请日：2007-10-30

    Applicant: INFECTION PREVENTION SYSTEMS I ,  HWANG FRANKLIN D ,  ARNDT DOUGLAS C

    Inventor： HWANG FRANKLIN D ,  ARNDT DOUGLAS C

    IPC: A61K49/00

    CPC classification number: A61K49/0063 ,  A01N25/00 ,  A61K49/0006 ,  A61K49/006

    Abstract: A hand cleansing formulation in the form of a soap/disinfectant (liquid, foam, cream or powder) in solution contains a marker agent (e.g., fluorescent or phosphorescent agent(s)) aggregated with a non-marker binder material. By vigorously scrubbing the hands together, as required by a proper hand washing procedure, the aggregates are dissociated to allow the measurement of the fluorescence/ phosphorescence intensity under an activation light source, i.e., UV, IR. This intensity measurement directly relates to the thoroughness of the hand scrubbing steps, thereby allowing the thoroughness of hand scrubbing during a hand washing event to be judged and monitored.

    Abstract translation: 溶液中肥皂/消毒剂（液体，泡沫，奶油或粉末）形式的手洗清洁剂含有与非标记粘合剂材料聚集的标记剂（例如荧光或磷光剂）。 通过适当的洗手步骤，按照需要强力地擦洗双手，将聚集体解离以允许测量活化光源下的荧光/磷光强度，即UV，IR。 这种强度测量直接关系到手洗步骤的彻底性，从而允许在洗手事件期间彻底地进行手洗，以进行判断和监视。

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