公开(公告)号：WO2017210019A1

公开(公告)日：2017-12-07

申请号：PCT/US2017/033986

申请日：2017-05-23

Applicant: BECTON, DICKINSON AND COMPANY

Inventor： ISAACSON, S. Ray ,  SHEVGOOR, Siddarth ,  BURKHOLZ, Jonathan Karl ,  SANDERS, Laurie

IPC: A61M25/01 ,  A61B5/06

CPC classification number: A61B5/062 ,  A61B5/489 ,  A61B8/0841 ,  A61B17/3403 ,  A61B2017/3413 ,  A61B2034/2051 ,  A61B2090/3929 ,  A61B2090/3954 ,  A61M25/0082 ,  A61M25/0127

Abstract: Devices, systems, and methods are described including an invasive medical device with a magnetic region. The magnetic region can include a discontinuity in the magnetic region providing a diameter transition, a plurality of spaced magnetic regions can be provided or the magnetic regions can be encoded with data. Systems and methods are described that include ways to read the data.

Abstract translation: 描述了包括具有磁性区域的侵入式医疗设备的设备，系统和方法。 磁性区域可以包括提供直径过渡的磁性区域中的不连续性，可以提供多个隔开的磁性区域或者磁性区域可以用数据编码。 描述的系统和方法包括读取数据的方式。

公开(公告)号：WO2016185478A1

公开(公告)日：2016-11-24

申请号：PCT/IL2016/050531

申请日：2016-05-19

Applicant: INNOVENTIONS LTD.

Inventor： YACHIA, Daniel ,  PONOMARENKO, Valentin

IPC: A61F2/04 ,  A61F2/82 ,  A61M27/00

CPC classification number: A61M25/0127 ,  A61F2/0018 ,  A61M25/04 ,  A61M27/008 ,  A61M2210/1085 ,  A61M2210/1089

Abstract: Disclosed is a bladder drainage apparatus comprising a tube including a hollow interior extending through the tube, a flexible anchor, which behaves spring-like, connected to or at one end of the tube, and a magnetic member connected to or at the other end of the tube. The tube is movable when the magnetic member is engaged by an external magnetic force, creating magnetic traction, and moving the tube, e.g., outward (from its original position, where the sphincter is typically closed), such that it holds open a sphincter, allovving urine to brain from the bladder, to the urethra, to outside of the body. When the external magnetic force is released, the magnetic engagement is terminated, and the force of the flexible anchor pulls the tube back to its original position, whereby the sphincter is again closed, and accordingly urine flow is stopped or otherwise limited.

Abstract translation: 公开了一种膀胱排液装置，其包括管，该管包括延伸穿过管的中空内部，柔性锚，其形状类似弹簧，连接到管的一端或其一端，以及磁性构件，其连接到或另一端 管子。 当磁性构件通过外部磁力接合，产生磁力牵引和移动管子时，例如向外（从其原始位置，括约肌通常关闭的位置）移动管子，使得管子保持打开括约肌， 将尿液从膀胱移至脑部，向尿道移至身体外部。 当外部磁力被释放时，磁性接​​合被终止，并且柔性锚杆的力将管拉回到其原始位置，由此括约肌再次闭合，因此尿流停止或以其他方式限制。

公开(公告)号：WO2016172217A1

公开(公告)日：2016-10-27

申请号：PCT/US2016/028448

申请日：2016-04-20

Applicant: SRI INTERNATIONAL

Inventor： PELRINE, Ronald, E. ,  WONG-FOY, Annjoe ,  HSU, Allen, L. ,  JOSEPH, Jose, P.

IPC: H01F7/127 ,  B23P19/04 ,  H01F7/02 ,  H01F7/04 ,  H02N15/00

CPC classification number: H01F7/0242 ,  A61B10/0233 ,  A61M25/0127 ,  B60L13/04 ,  H01F7/0236 ,  H01F7/06 ,  H02N15/00

Abstract: A microrobot assembly system includes a substrate containing conductive traces formed into at least one holding zone and one moving zone, a diamagnetic layer on the substrate, at least two magnetic structures movable across the diamagnetic layer in response to voltages applied to the conductive traces, wherein the holding zone holds one of the magnetic structures and the moving zone allows another of the magnetic structures to attach to the magnetic structure being held. The system may include a plate spaced above the substrate and rails to guide the moving magnetic structures.

Abstract translation: 微型机器人组装系统包括：衬底，其包含形成在至少一个保持区域和一个移动区域中的导电迹线，衬底上的抗磁性层，响应于施加到导电迹线的电压而跨越抗磁性层移动的至少两个磁性结构，其中 保持区保持其中一个磁性结构，并且移动区允许另一磁结构附着在被保持的磁结构上。 该系统可以包括在基板上方间隔的板和轨道以引导移动的磁性结构。

公开(公告)号：WO2016049297A1

公开(公告)日：2016-03-31

申请号：PCT/US2015/051910

申请日：2015-09-24

Applicant: IMRICOR MEDICAL SYSTEMS, INC.

Inventor： KIMMEL, Scott ,  PAGE, Douglas A.

IPC: A61M25/098

CPC classification number: A61M25/0136 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61B2090/3966 ,  A61M25/0127 ,  A61M25/0147

Abstract: An MR compatible steerable sheath with elastomeric member is provided. The elastomeric member is configured to serve as a reservoir and receive contrast media therewithin. The elastomeric member is positioned on the distal end of the steerable sheath and may circumferentially surround the sheath shaft or be offset from a longitudinal axis thereof. In operation, the contrast media allows a user to view the distal tip of the steerable sheath by virtue of the contrast media contained within the elastomeric member.

Abstract translation: 提供具有弹性体构件的MR兼容的可转向护套。 弹性体构件构造成用作储存器并在其中接收造影剂。 弹性体构件定位在可转向鞘的远端上，并且可以周向地围绕护套轴或者从其纵向轴线偏移。 在操作中，造影剂允许用户通过包含在弹性体构件内的造影剂来观察可转向护套的远端。

公开(公告)号：WO2015161927A4

公开(公告)日：2016-02-11

申请号：PCT/EP2015000845

申请日：2015-04-23

Applicant: MARVIS MEDICAL GMBH

Inventor： DÜRING KLAUS ,  DLAIKAN-CAMPOS NASIB ,  VAN DIJK MAARTEN

IPC: A61L31/18

CPC classification number: A61B90/39 ,  A61B5/055 ,  A61B2090/3954 ,  A61L31/022 ,  A61L31/026 ,  A61L31/10 ,  A61L31/14 ,  A61L31/18 ,  A61M25/0127 ,  A61M25/09 ,  A61M2025/09166 ,  G01R33/287

Abstract: The invention relates to a rod-shaped body comprising a central portion and a peripheral portion, wherein the central portion is arranged in the center of the rod-shaped body and is surrounded by the peripheral portion. Both the central portion and the peripheral portion substantially extend across the entire length of the rod-shaped body. The central portion has at least one non-metallic fiber bundle that is embedded in a non-ferromagnetic matrix material. The matrix material is doped with marker particles. The peripheral portion has at least one undoped, non-ferromagnetic matrix material. The diameter of the central portion is less than or equal to 0.2 mm, preferably less than or equal to 0.15 mm, and even more preferably, is less than or equal to 0.1 mm, and in particular less than or equal to 0.08 mm.

Abstract translation: 根据本发明的棒状体包括一中心部分和周边部分，所述中心部分被设置在棒状体的中心，并且由周缘部包围。 二者的中心部分和周边部分上延伸大致棒状体的整个长度。 的中央部分具有至少一个嵌入在非铁磁基体材料，非金属纤维束。 所述基质材料掺杂有标记颗粒。 外围部分具有在未掺杂的，非铁磁性基体材料的至少一种。 中央部分的直径比小于或等于0.2mm，优选小于或等于0.15毫米，甚至比更优选小于或等于0.1毫米，特别是小于或等于0.08毫米。

公开(公告)号：WO2015198333A1

公开(公告)日：2015-12-30

申请号：PCT/IL2015/050662

申请日：2015-06-25

Applicant: THERACOAT LTD.

Inventor： HAKIM, Gil ,  DOLBERG, Yosh ,  MALCHI, Nadav

IPC: A61F2/82 ,  A61M25/01 ,  A61M31/00

CPC classification number: A61M27/008 ,  A61F2/04 ,  A61F2/82 ,  A61F2/94 ,  A61F2002/047 ,  A61F2002/048 ,  A61M25/0102 ,  A61M25/0127 ,  A61M25/0136 ,  A61M31/00 ,  A61M39/10 ,  A61M2025/0293

Abstract: There are provided a connectable catheter system, device and methods of use thereof. The connectable catheter system, comprising: an intermediary catheter comprising an external section and a tip section, the tip section is configured to be inserted into a body of a subject; and a reconnectable indwelling stent comprising a connecting section and a target section, the target section being configured to be located within a body of the subject, wherein the connecting section of the reconnectable indwelling stent is configured to reversibly connect, within the subject body, to the tip section of the intermediary catheter to form a continuous conduit between the intermediary catheter and the reconnectable indwelling stent.

Abstract translation: 提供了可连接的导管系统，装置及其使用方法。 可连接导管系统，包括：中间导管，其包括外部部分和尖端部分，所述末端部分被配置成插入到受试者的身体中; 以及可重新连接的留置支架，其包括连接部分和目标部分，所述目标部分被配置为位于所述对象的主体内，其中所述可重新连接的留置支架的所述连接部分构造成在所述主体内可逆地连接到所述主体内 中间导管的尖端部分，以在中间导管和可重新连接的留置支架之间形成连续导管。

公开(公告)号：WO2015193047A1

公开(公告)日：2015-12-23

申请号：PCT/EP2015/061049

申请日：2015-05-20

Applicant: BIOTRONIK SE & CO. KG

Inventor： FRUENDT, Carsten ,  TRIP, Erik

IPC: A61N1/372 ,  A61M25/00 ,  A61N1/05 ,  A61M25/06

CPC classification number: A61N1/056 ,  A61M25/0108 ,  A61M25/0113 ,  A61M25/0127 ,  A61M25/0662 ,  A61M25/09041 ,  A61M25/10 ,  A61M2025/0188 ,  A61N1/372

Abstract: The invention refers to an elongated guide sheath for delivering at least one medical instrument to a body lumen. For reliable and cost effective implantation of an electrode at the AV septum the inventive guide sheath (10, 60, 70) forms a first guiding sleeve (11, 61,71) and a second guiding sleeve (12, 62, 72) at least partly separated by a shared wall section (16, 66, 76), wherein the longitudinal axis of the first guiding sleeve (11, 61, 71) and the longitudinal axis of the second guiding sleeve (12, 62, 72) run parallel to a longitudinal guide sheath axis (14), wherein the wall of the first guiding sleeve (11, 61, 71) and/or of the second guiding sleeve (12, 62, 72) each comprises a slit (17, 18) which runs along at least part of the length of the respective guiding sleeve (11, 61, 71, 81, 12, 62, 72). Further, a system comprising the above guide sheath, a first catheter and/or guide wire and a second catheter or electrode is proposed.

Abstract translation: 本发明涉及一种用于将至少一种医疗器械递送到体腔的细长引导护套。 为了在AV隔膜处可靠且经济地植入电极，本发明的引导护套（10,60,70）至少形成第一引导套筒（11,61,71）和第二引导套筒（12,62,72） 部分地由共同的壁部分（16,66,76）分开，其中第一引导套筒（11,61,71）的纵向轴线和第二引导套筒（12,62,72）的纵向轴线平行于 纵向引导护套轴线（14），其中第一引导套筒（11,61,71）的壁和/或第二引导套筒（12,62,72）的每个包括狭缝（17,18），该狭缝（17,18） 沿着相应导向套筒（11,61,71,81,12,62,72）的长度的至少一部分。 此外，提出了包括上述引导护套，第一导管和/或引导线和第二导管或电极的系统。

公开(公告)号：WO2015138998A1

公开(公告)日：2015-09-17

申请号：PCT/US2015/020604

申请日：2015-03-13

Applicant: TVA MEDICAL, INC.

Inventor： PATE, Thomas, Diffley

IPC: A61M25/092

CPC classification number: A61M25/0127 ,  A61B17/11 ,  A61B18/1492 ,  A61B2017/00778 ,  A61B2017/00876 ,  A61B2018/00345 ,  A61B2018/00577 ,  A61B2018/00595 ,  A61M1/3655

Abstract: Described here are devices, systems, and methods for forming a fistula between two blood vessels. Generally, the systems may comprise a first catheter and a second catheter, which may comprise one or more fistula-forming elements. The first and second catheters may comprise one or more magnets, which may be used to assist in bringing the first and catheters in closer proximity to facilitate fistula formation. In some variations, the magnet may have a plurality of magnetic domains each characterized by a magnetic flux vector, with the magnetic flux vectors of the magnet passing through a common magnetic origin.

Abstract translation: 这里描述了用于在两个血管之间形成瘘的装置，系统和方法。 通常，系统可以包括第一导管和第二导管，其可以包括一个或多个瘘形成元件。 第一和第二导管可以包括一个或多个磁体，其可以用于帮助使第一和导管更靠近以促进瘘形成。 在一些变型中，磁体可以具有多个磁畴，每个磁畴的特征在于磁通矢量，其中磁体的磁通量矢量通过公共磁性原点。

公开(公告)号：WO2015130829A1

公开(公告)日：2015-09-03

申请号：PCT/US2015/017582

申请日：2015-02-25

Applicant: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.

Inventor： DENO, D. Curtis ,  BALACHANDRAN, Ram Kumar

IPC: A61B5/042 ,  A61B5/06 ,  A61B5/00 ,  A61N1/04 ,  A61B19/00

CPC classification number: A61B5/0422 ,  A61B5/0044 ,  A61B5/04011 ,  A61B5/04012 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/062 ,  A61B5/068 ,  A61B5/6852 ,  A61B5/6858 ,  A61B5/7239 ,  A61B18/1492 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2562/0209 ,  A61B2562/0214 ,  A61B2562/046 ,  A61M25/0127 ,  A61M2025/0166

Abstract: A method for determining electrophysiology properties of tissue comprising acquiring electrical signal data from a plurality of electrodes (130) of one or more catheters, determining at least one electrode clique from the plurality of adjacent electrodes (136), computing local conduction velocity vectors for the at least one electrode clique (138), determining at least one catheter orientation independent indicator from which to classify an arrhythmia source based on one or more of an angular dependence parameter associated with a flow field of the local velocity conduction vectors, an eccentricity parameter reflecting the uniformity of local conduction velocity, and divergence and curl-like sums or closed path integral parameters associated with the local velocity vectors, and displaying a rhythm classification responsive to catheter movement thereby facilitating identification of types and causes of arrhythmia disorders.

Abstract translation: 一种用于确定组织的电生理学性质的方法，包括从多个导管的多个电极（130）获取电信号数据，确定来自所述多个相邻电极（136）的至少一个电极组，计算所述多个导电速度矢量 至少一个电极组（138），确定至少一个导管取向独立指示器，根据与局部速度传导矢量的流场相关联的角度相关参数中的一个或多个来分类心律失常源，反射 局部传导速度的均匀性，以及与局部速度矢量相关的发散度和卷曲状总和或闭合路径积分参数，以及响应于导管移动显示节律分类，从而有助于识别心律失常障碍的类型和原因。

公开(公告)号：WO2015124188A1

公开(公告)日：2015-08-27

申请号：PCT/EP2014/053320

申请日：2014-02-20

Applicant: BRAINLAB AG

Inventor： THOMSON, Rowena ,  RUBE, Martin ,  MITTERMEYER, Stephan

IPC: A61M25/00

CPC classification number: A61M25/008 ,  A61M25/002 ,  A61M25/0102 ,  A61M25/0108 ,  A61M25/0127 ,  A61M25/04 ,  A61M2025/0042 ,  A61M2205/0211 ,  A61M2210/0693

Abstract: The invention relates to an agent delivery catheter, comprising a first hollow tube and a second hollow tube 2 which protrudes from a distal opening of the first hollow tube 1 and defines an agent delivery lumen 3 extending along the entire length of the catheter, wherein: the distal end of the first tube 1 is coupled to the second tube 2 to form an annular cavity 4 between the first tube 1 and the second tube 2, the annular cavity 4 being configured to accommodate a retractable stylet shaft 5; a ceramic member 6 which is disposed at the distal end of the first tube 1, in particular distally with respect to the distal opening of the first tube 1, encompasses the second tube 2 and couples the first tube 1 to the second tube 2, in particular via a third hollow tube 23 which encompasses the first tube 1 and the ceramic member 6; and a protective shrink-fit tube 7 is disposed radially on the outside of the ceramic member 6 and extends over at least the length of the ceramic member 6. Another aspect of the invention relates to an agent delivery system comprising such a catheter and a stylet which comprises a handle portion 15 and a ceramic shaft 5 which is configured to be accommodated within the annular cavity 4 of said catheter, wherein a shrink-fit tube 6 is disposed radially on the outside of the ceramic shaft 5 and in particular extends over at least the length of the ceramic shaft 5.

Abstract translation: 本发明涉及一种药剂递送导管，其包括第一中空管和从第一中空管1的远侧开口突出的第二中空管2，并且限定沿导管的整个长度延伸的药剂输送腔3，其中： 第一管1的远端联接到第二管2，以在第一管1和第二管2之间形成环形空腔4，环形空腔4构造成容纳可伸缩的探针轴5; 设置在第一管1的远端，特别是相对于第一管1的远端开口的远端的陶瓷构件6包围第二管2，并将第一管1连接到第二管2，以 特别是通过包围第一管1和陶瓷构件6的第三中空管23; 并且保护性收缩配合管7径向设置在陶瓷构件6的外侧上，并延伸至陶瓷构件6的至少长度。本发明的另一方面涉及一种包括这种导管和探针 其包括手柄部分15和陶瓷轴5，其被构造成容纳在所述导管的环形空腔4内，其中收缩配合管6径向设置在陶瓷轴5的外侧上，并且特别地延伸到 至少陶瓷轴5的长度。