FILTRATION ASSEMBLY AND FILTRATION SYSTEM INCLUDING THE SAME

    公开(公告)号:WO2019108082A1

    公开(公告)日:2019-06-06

    申请号:PCT/RU2017/000891

    申请日:2017-12-01

    IPC分类号: B01D63/08

    摘要: A tangential flow filtration assembly (100) is provided herein. The tangential flow filtration assembly includes a first and second winding tangential flow channel (116, 118) having an inlet (126, 128) at an endpoint the respective tangential flow channel and an outlet (136, 138) at an opposite endpoint of the respective tangential flow channel, the tangential flow channels further having a first cross- sectional area at the inlet and a second cross-sectional area at the outlet. The tangential flow filtration assembly further includes a filtration membrane positioned between the first and second tangential flow channels. The first cross-sectional area of the first tangential flow channel is greater than the second cross-sectional area of the first tangential flow channel, and the first cross-sectional area of the second tangential flow channel is less than the second cross-sectional area of the second tangential flow channel.

    人工肺の製造方法
    2.
    发明申请

    公开(公告)号:WO2018168533A1

    公开(公告)日:2018-09-20

    申请号:PCT/JP2018/008099

    申请日:2018-03-02

    发明人: 安齊 崇王

    IPC分类号: A61M1/18

    摘要: 外表面と、内腔を形成する内表面と、前記外表面と前記内表面とを連通する開口部と、を備えた複数のガス交換用多孔質中空糸膜を有する人工肺の製造方法は、抗血栓性高分子化合物のコロイドと、金属カチオンまたはアンモニウムカチオンを含む水溶性塩と、を含む溶液を、前記外表面および前記内表面のいずれか一方に塗布することを含む。本発明によれば、中空糸膜に対する抗血栓性高分子化合物のコート量を増加させることができる手段が提供される。

    CARTRIDGES AND SYSTEMS FOR OUTSIDE-IN FLOW IN MEMBRANE-BASED THERAPIES
    3.
    发明申请
    CARTRIDGES AND SYSTEMS FOR OUTSIDE-IN FLOW IN MEMBRANE-BASED THERAPIES 审中-公开
    基于膜的治疗外部流入的药物和系统

    公开(公告)号:WO2017048224A1

    公开(公告)日:2017-03-23

    申请号:PCT/US2015/050004

    申请日:2015-09-14

    IPC分类号: B01D61/28 B01D63/02 A61M1/16

    摘要: Embodiments of the invention pertain to cartridges, systems and methods for performing hemodialysis and related extracorporeal blood treatment modalities and therapies, in which blood flows in the inter fiber space and dialysate flows in the lumens of hollow fibers. Appropriate connectors and fitting orientations may be provided. There may be provided orbital distributors, fanning of fibers, and features to promote uniformity of fiber spacing in the fiber bundle. Orbital distributors may contain contoured surfaces, flow redirectors, non-uniform-conductance flow elements, through-wall distributors, and other features. There may be subdivision of the fiber bundle into two groups of fibers with separate control fluid to each group. Appropriate systems may be provided for various therapies. Flow past the fibers may be parallel, transverse or other configuration. These various features may enable long-term application to all dialysis and ultrafiltration related therapies, and also to other therapies and to applications including implantables, portables and wearables.

    摘要翻译: 本发明的实施例涉及用于进行血液透析和相关的体外血液处理模式和疗法的药筒,系统和方法,其中血液在纤维间隙中流动并且透析液在中空纤维内腔中流动。 可以提供适当的连接器和配合方向。 可以提供轨道分配器,纤维的扇形和特征,以促进纤维束中的纤维间隔的均匀性。 轨道分配器可以包含轮廓表面,流动重定向器,非均匀电导流动元件,通孔分配器和其他特征。 可以将纤维束分成两组纤维,每组具有单独的控制流体。 可以为各种疗法提供适当的系统。 通过纤维的流动可以是平行的,横向的或其它构型。 这些各种特征可以使得能够长期应用于所有透析和超滤相关疗法,以及其它疗法以及包括植入物,便携式和可穿戴物在内的应用。

    AFFINITY CHROMATOGRAPHY DEVICES
    4.
    发明申请
    AFFINITY CHROMATOGRAPHY DEVICES 审中-公开
    亲水色谱装置

    公开(公告)号:WO2017014817A1

    公开(公告)日:2017-01-26

    申请号:PCT/US2016/026863

    申请日:2016-04-11

    摘要: The present invention is directed to affinity chromatography devices that separate a targeted protein or antibody from an aqueous mixture containing the targeted protein or antibody, The chromatography device may contain a stacked membrane assembly or a wound membrane assembly. The membrane assemblies include at least one polymer membrane that contains therein inorganic particles. The polymer membrane and/or the inorganic particles have an affinity Iigand bonded thereto. The affinity Iigand may be a protein, an antibody, or a polysaccharide that reversibly binds to the targeted protein or antibody. The chromatography device may be repeatedly used and may be cleaned with a caustic solution between uses. The chromatography devices may have a dynamic binding capacity (DBC) of at least 30 mg/ml (or 0.07 micromol/ml) at 10% breakthrough at a residence time of 20 seconds or less.

    摘要翻译: 本发明涉及从含有目标蛋白质或抗体的水性混合物中分离靶向蛋白质或抗体的亲和层析装置。色谱装置可包含层叠膜组件或缠绕膜组件。 膜组件包括至少一个在其中含有无机颗粒的聚合物膜。 聚合物膜和/或无机颗粒具有与其结合的亲和性配体。 亲和力配体可以是可逆结合靶向蛋白质或抗体的蛋白质,抗体或多糖。 色谱装置可以重复使用,并且可以在使用之间用苛性碱溶液清洗。 在20秒或更短的停留时间下,色谱装置可以具有至少30mg / ml(或0.07微摩尔/ ml)的10%穿透的动态结合能力(DBC)。

    METHODS AND APPARATUSES FOR FUEL GAS CONDITIONING VIA MEMBRANES
    5.
    发明申请
    METHODS AND APPARATUSES FOR FUEL GAS CONDITIONING VIA MEMBRANES 审中-公开
    燃料气体通过膜的调节方法和装置

    公开(公告)号:WO2017007688A1

    公开(公告)日:2017-01-12

    申请号:PCT/US2016/040519

    申请日:2016-06-30

    申请人: UOP LLC

    IPC分类号: B01D53/22 B01D63/00

    摘要: A method for conditioning natural gas into fuel gas, where the method includes the step of: delivering a natural gas stream including both CO 2 and C2+ hydrocarbons to a membrane separation assembly; and separating the natural gas stream into the following streams: (i) a first permeate stream, (ii) a second permeate stream, and (iii) a residual stream. The first permeate stream includes CO 2 removed from the natural gas stream. The second permeate stream includes methane at a greater concentration than a concentration of methane in the natural gas stream. The residual stream contains C2+ hydrocarbons at a greater concentration than a concentration of C2+ hydrocarbons in the natural gas stream.

    摘要翻译: 将天然气调节成燃料气体的方法,其中所述方法包括以下步骤:将包括CO 2和C 2 +烃的天然气流输送到膜分离组件; 并将天然气流分离成以下物流:(i)第一渗透物流,(ii)第二渗透物流,和(iii)残余物流。 第一渗透物流包括从天然气流中除去的CO 2。 第二渗透物流包括比天然气流中的甲烷浓度更高的甲烷。 残余物流含有比天然气流中C2 +烃浓度更高浓度的C2 +烃。

    중공사막 모듈
    7.
    发明申请
    중공사막 모듈 审中-公开
    中空纤维膜模块

    公开(公告)号:WO2015147511A1

    公开(公告)日:2015-10-01

    申请号:PCT/KR2015/002840

    申请日:2015-03-23

    IPC分类号: B01D69/08 B01D63/04

    摘要: 본 발명은 중공사막 모듈에 관한 것으로서, 상기 중공사막 모듈은 제1 유체 유입구와 제1 유체 유출구 및 제2 유체 유입구와 제2 유체 유출구를 포함하는 하우징부, 그리고 다수의 중공사막을 포함하며, 상기 제1 유체가 상기 중공사막 내부로 흐르고 상기 제2 유체가 상기 중공사막 외부로 흐르도록 상기 하우징 내부에 배치된 중공사막 다발을 포함하며, 상기 중공사막 다발은, 양쪽 끝이 막혀 있고 측면에 다수의 기공을 포함하는 다공성 튜브를 더 포함한다. 상기 중공사막 모듈은 중공사막 다발 외부로 흐르는 유체가 침투하기 어려운 영역을 제거하여 상기 유체가 균일하게 흐를 수 있도록 한다. 이에 따라, 상기 중공사막이 고집적된 경우에도 상기 중공사막 모듈의 성능을 극대화할 수 있다.

    摘要翻译: 本发明涉及中空纤维膜组件。 中空纤维膜组件包括:具有第一流体入口和第一流体出口的壳体部分,以及第二流体入口和第二流体出口; 以及包括多个中空纤维膜的中空纤维膜束,并且设置在壳体内部,使得第一流体朝向中空纤维膜的内部流动,第二流体朝向中空纤维膜的外部流动 其中,所述中空纤维膜束还包括其两端被封闭的多孔管,并且在其横向侧上具有多个孔。 由于去除了流向中空纤维膜束的外部的流体难以通过的区域,所以中空纤维膜组件能够使流体均匀地流入其中。 因此,即使中空纤维膜以高密度积聚,中空纤维膜组件的性能也可以最大化。

    SINGLE END, SHELL-SIDE FEED, HOLLOW FIBER MEMBRANE SEPARATION MODULE
    8.
    发明申请
    SINGLE END, SHELL-SIDE FEED, HOLLOW FIBER MEMBRANE SEPARATION MODULE 审中-公开
    单端,外壳进料,中空纤维隔膜模块

    公开(公告)号:WO2015031133A1

    公开(公告)日:2015-03-05

    申请号:PCT/US2014/051911

    申请日:2014-08-20

    IPC分类号: B01D63/02

    摘要: A shell-side feed, hollow fiber, fluid separation module arranged for counter-flow includes a hollow fiber membrane bundle with each individual hollow fiber membrane (31) in the bundle (30) having an open fiber end (39) and a sealed fiber end (43), The open fiber ends (39) are encapsulated in a tubesheet (19) located toward the permeate fluid outlet end (17) of the module (10). The sealed fiber ends (43) are tubesheet-free, uniformly spaced, and located toward the non-permeate fluid outlet end (41) of the module (10).

    摘要翻译: 布置为逆流的壳侧进料,中空纤维,流体分离组件包括中空纤维膜束,其中在束(30)中的每个单独的中空纤维膜(31)具有开纤维端(39)和密封纤维 端部(43),开口纤维端部(39)被封装在位于模块(10)的渗透液出口端(17)的管板(19)中。 密封的纤维端部(43)是无管板,均匀间隔开的并且朝向模块(10)的非渗透流体出口端(41)定位。

    濾過装置及びこれを用いた浸漬式濾過方法
    10.
    发明申请
    濾過装置及びこれを用いた浸漬式濾過方法 审中-公开
    过滤装置和使用相同的过滤方法

    公开(公告)号:WO2014192433A1

    公开(公告)日:2014-12-04

    申请号:PCT/JP2014/060295

    申请日:2014-04-09

    IPC分类号: B01D63/02 B01D65/02 C02F1/44

    摘要: 中空糸膜表面の洗浄能力に優れ、高い濾過能力を維持することができる濾過装及びこの濾過装置を用いた浸漬式濾過方法の提供を目的とする。本発明は、一方向に引き揃えられた状態で保持される複数本の中空糸膜を有する濾過モジュールと、この濾過モジュールの下方から気泡を供給する気体供給器とを備える浸漬式の濾過装置であって、上記気体供給器から供給される気泡が、濾過モジュールに衝突後複数の気泡に分割される濾過装置である。上記気体供給器から供給される気泡の平均水平径が上記濾過モジュールの複数本の中空糸膜の保持部分の最大間隔より大きいとよい。

    摘要翻译: 本发明的目的是提供:具有优异的中空纤维膜清洗能力并且能够保持高过滤能力的过滤装置; 以及使用所述过滤装置的浸渍过滤方法。 本发明是一种浸没式过滤装置,其具有将多个中空纤维膜均匀地保持在一个方向上的过滤模块,以及用于从过滤模块下方供给气泡的气体供给装置。 从气体供应商提供的气泡在与过滤模块冲击后分为多个气泡。 从气体供给器供给的气泡的平均水平直径优选大于过滤模块中的多个中空纤维膜的被保持部的最大间隔。