Abstract:
Described herein is a pumpable and/or flowable suspension comprising about 10-60 wt% of beta glucan (BG) that when diluted achieves a filterability ratio less than about 1.5. Further described herein is a pumpable and/or flowable suspension comprising about 10-60 wt% of BG wherein greater than 50% of ultimate viscosity can be recovered after running specified dilution procedure for one pass and greater than 70% of ultimate viscosity after two passes.
Abstract:
The present invention relates to novel oligomers of Neisseria meningitidis serogroup Y capsular polysaccharide repeating unit (Men-Y oligomers) and process for synthesizing novel Men- Y oligomers. In particular, the present invention relates to the chemical synthesis of the tetramer of Men- Y capsular polysaccharide repeating unit capable of being used as a candidate in the development of semisynthetic or fully synthetic conjugate vaccine against meningococcal serogroup Y bacterial infection.
Abstract:
The present invention provides an improved method for the capturing and/or enriching of glycans from glycoproteins or biological materials carrying glycoproteins. In one embodiment, the method for capture and/or enrichment of glycans comprises the steps of: contacting the glycoprotein sample with an oxidizing agent such as periodate, binding the oxidized products to magnetic, paramagnetic or polymeric beads which could be hydrazide functionalized, separating the glycans from glycoproteins using chemical reaction involving acids or enzymatic reaction such as using PNGase to obtain glycans bound to beads, finally labeling bead bound glycans and cleaving the glycans from the beads. A further embodiment discloses a method for detecting and analyzing glycans using multiplexed capillary electrophoresis with laser induced fluorescence (CE-LIF) system comprising micellar electrokinetic chromatography (MEKC) in combination with capillary zone electrophoresis (CZE) or capillary gel electrophoresis (CGE).
Abstract:
The invention provides lubricating compositions and methods of use thereof in man or in animals. Specifically, provided are lubricating compositions comprising effective amounts of chondroitin sulfate and hyaluronan, and optionally include N-acetyl D-glucosamine.
Abstract:
The present invention relates to oligo- and polysaccharides containing amine groups. More particularly, the present invention is directed towards a new process to manufacture cationic cellulose oligomers. The new cationic oligo- or polysaccharides are shown to be useful ingredients in various aqueous compositions, inter alia as ingredients for personal care compositions.