公开(公告)号：WO2021247685A1

公开(公告)日：2021-12-09

申请号：PCT/US2021/035425

申请日：2021-06-02

Applicant: BOSTON SCIENTIFIC SCIMED, INC. ,  BOLT MEDICAL, INC.

Inventor： MASSIMINI, Daniel, Frank ,  MCGOWAN, Roger ,  FULLER, Jeffrey, Steven ,  LINDQUIST, Jeffrey, S. ,  PARSONS, Dave ,  SCHULTHEIS, Eric

IPC: A61B18/02 ,  A61B18/04 ,  A61B18/042 ,  A61B18/1492 ,  A61B18/245 ,  A61B18/26 ,  A61B2017/00154 ,  A61B2018/00023 ,  A61B2018/00077 ,  A61B2018/00095 ,  A61B2018/00101 ,  A61B2018/00154 ,  A61B2018/00166 ,  A61B2018/0022 ,  A61B2018/00255 ,  A61B2018/00285 ,  A61B2018/00345 ,  A61B2018/00369 ,  A61B2018/00386 ,  A61B2018/00422 ,  A61B2018/0066 ,  A61B2018/2211 ,  A61B2018/2261 ,  A61B2018/2266 ,  A61B2018/2272 ,  A61B2018/263 ,  A61B2018/266 ,  A61B2090/0809

Abstract: A catheter system (100) for treating a treatment site (106) within or adjacent to the vessel wall of a blood vessel (108), or the heart valve, includes an energy source (124), a balloon (104), an energy guide (122A), and a balloon integrity protection system (142). The energy source (124) generates energy, The balloon (104) is positionable substantially adjacent to the treatment site (106). The balloon (104) has a balloon wall (130) that defines a balloon interior (146). The balloon (104) is configured to retain a balloon fluid (132) within the balloon interior (146). The energy guide (122A) is configured to receive energy from the energy source (124) and guide the energy into the balloon interior (146) so that plasma is formed in the balloon fluid (132) within the balloon interior (146). The balloon integrity protection system (142) is operatively coupled to the balloon (104). The balloon integrity protection system (142) is configured to inhibit rupture of the balloon (104) due to the plasma formed in the balloon fluid (132) within the balloon interior (146) during use of the catheter system (100).

公开(公告)号：WO2021257425A1

公开(公告)日：2021-12-23

申请号：PCT/US2021/037169

申请日：2021-06-14

Applicant: BOSTON SCIENTIFIC SCIMED, INC. ,  BOLT MEDICAL, INC.

Inventor： MASSIMINI, Daniel, Frank ,  MCGOWAN, Roger ,  SHAO, Haiping ,  BEEKMAN, Darrin, Dale ,  COOK, Christopher, A.

IPC: A61B18/04 ,  A61B18/14 ,  A61B18/18 ,  A61B18/20 ,  A61B18/00 ,  A61B18/12 ,  A61B18/042 ,  A61B18/1492 ,  A61B18/245 ,  A61B2018/00166 ,  A61B2018/0022 ,  A61B2018/00345 ,  A61B2018/00583 ,  A61B2018/1213 ,  A61B5/0075

Abstract: A catheter system (100) for placement within a treatment site (106) at a vessel wall (208A) or a heart valve includes an energy source (124), a balloon (104), an energy guide (122 A), and a tissue identification system (142). The energy source (124) generates energy. The balloon (104) is positionable substantially adjacent to the treatment site (106). The balloon (104) has a balloon wall (130) that defines a balloon interior (146). The balloon (104) is configured to retain a balloon fluid (132) within the balloon interior (146). The energy guide (122A) is configured to receive energy from the energy source (124) and guide the energy into the balloon interior (146) so that plasma is formed in the balloon fluid (132) within the balloon interior (146). The tissue identification system (142) is configured to spectroscopically analyze tissue within the treatment site (106). A method for treating a treatment site (106) within or adjacent to a vessel wall (208A) or a heart valve can utilize any of the catheter systems (100) described herein.

公开(公告)号：WO2021150502A1

公开(公告)日：2021-07-29

申请号：PCT/US2021/013944

申请日：2021-01-19

Applicant: BOLT MEDICAL, INC.

Inventor： COOK, Christopher, A.

IPC: A61B18/26 ,  A61B18/24 ,  A61B17/22022 ,  A61B18/245 ,  A61B2017/00176 ,  A61B2017/00185 ,  A61B2017/0019 ,  A61B2017/00194 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/00285 ,  A61B2018/00386 ,  A61B2018/00422 ,  A61B2018/00732 ,  A61B2018/00761 ,  A61B2018/2211 ,  A61B2018/2261 ,  A61B2018/2272 ,  A61B2018/263 ,  A61B2018/266

Abstract: A catheter system (100) for treating a vascular lesion (106) within or adjacent to a vessel wall (108) includes an energy source (124), a plurality of energy guides (122A) and a system controller (126). The energy source (124) generates energy that is received by the energy guides (122A). The system controller (126) controls the energy source (124) so that the energy is sequentially directed to each of the plurality of energy guides (122A) in an advancing wavefront. The system controller (126) controls a firing rate of the energy source (124) to each of the plurality of energy guides (122A). The system controller (126) can control a firing sequence to the plurality of energy guides (122A) so that the advancing wavefront is generated toward the vascular lesion (106) from near a balloon proximal end (104P) and from near a balloon distal end (104D). The system controller (126) can control the energy source (124) so that the energy from the energy source (124) is alternatively directed to at least two of the plurality of energy guides (122A) at a different firing energy level from one another. The energy level can be based on pulse width, wavelength and/or amplitude of the energy pulse(s).

公开(公告)号：WO2021202248A1

公开(公告)日：2021-10-07

申请号：PCT/US2021/024216

申请日：2021-03-25

Applicant: BOLT MEDICAL, INC.

Inventor： SCHULTHEIS, Eric ,  BACHER, Gerald D.

IPC: A61B18/26 ,  A61B18/04 ,  A61B18/14 ,  A61B90/00 ,  A61N1/05 ,  A61B18/00 ,  A61B18/12 ,  A61B18/042 ,  A61B18/1492 ,  A61B18/245 ,  A61B2017/00026 ,  A61B2017/00039 ,  A61B2017/00154 ,  A61B2018/0022 ,  A61B2018/00345 ,  A61B2018/00369 ,  A61B2018/00386 ,  A61B2018/00422 ,  A61B2018/00642 ,  A61B2018/00708 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1213 ,  A61B2018/263 ,  A61B2018/266 ,  A61B2090/0809 ,  A61N1/057

Abstract: A catheter system (100) for treating a treatment site (106) within or adjacent to a vessel wall (108) or heart valve includes an energy source (124), an inflatable balloon (104), an energy guide (122 A), and an electrical analyzer assembly (142). The energy source (124) generates energy. The inflatable balloon (104) is positionable substantially adjacent to the treatment site (106). The inflatable balloon (104) has a balloon wall (130) that defines a balloon interior (146). The balloon interior (146) receives a balloon fluid (132). The energy guide (122A) is configured to receive energy from the energy source (124) and guide the energy into the balloon interior (146). The electrical analyzer assembly (142) is configured to monitor a condition of the inflatable balloon (104) during use of the catheter system (100). The electrical analyzer assembly (142) includes a first electrode (158), a second electrode (160), and an impedance detector (162) that is electrically coupled to the first electrode (158) and the second electrode (160). The impedance detector (162) is configured to detect impedance between the first electrode (158) and the second electrode (160).

公开(公告)号：WO2021122491A1

公开(公告)日：2021-06-24

申请号：PCT/EP2020/086059

申请日：2020-12-15

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： TSCHIDA, Adam

IPC: A61B18/24 ,  A61B18/26 ,  A61B18/00 ,  A61B18/245 ,  A61B2018/00345 ,  A61B2018/263

Abstract: The present disclosure relates generally to the use of medical devices for the treatment of vascular conditions. In particular, the present disclosure provides devices and methods for using laser-induced pressure waves created within a sheath to disrupt intimal and medial calcium within the vasculature.

公开(公告)号：WO2022207471A1

公开(公告)日：2022-10-06

申请号：PCT/EP2022/057857

申请日：2022-03-25

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： CRONE, Tyler West

IPC: A61B18/24 ,  A61B18/26 ,  A61B18/245 ,  A61B2018/00196 ,  A61B2018/0041 ,  A61B2018/00577 ,  A61B2018/263 ,  A61B2018/266

Abstract: A vascular therapy device (10) includes a catheter (12) including at least one optical fiber(18) with a light output aperture (20). A containment sheath (14) has a sheath opening (18) disposed at an end thereof. The catheter is disposed inside the containment sheath and movable relative to the containment sheath to extend the light output aperture beyond the sheath opening such that the light output aperture is outside of the containment sheath. A safety sensor (22) is configured to detect whether the light output aperture is in a safe zone inside the containment sheath.

公开(公告)号：WO2022002653A1

公开(公告)日：2022-01-06

申请号：PCT/EP2021/066741

申请日：2021-06-21

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： BHARAT, Shyam ,  CHEN, Alvin ,  ZHENG, Mingxin ,  ERKAMP, Ramon Quido

IPC: A61B18/24 ,  A61B17/3207 ,  A61B18/245 ,  A61B2017/00128 ,  A61B2018/00345 ,  A61B2018/00642 ,  A61B2018/0066 ,  A61B2018/00785 ,  A61B2018/00904 ,  A61B2090/378 ,  A61B5/0095

Abstract: Systems and methods for laser catheter treatment in a vessel lumen. The method includes inserting the laser catheter within the vessel lumen to a location of a treatment area; presenting an image of the treatment area within the vessel lumen based on using an ultrasound (US) imaging system; and, detecting, in real-time, a bubble cloud that is a function of the laser catheter operation (at a prescribed speed and controlling a fluence and a pulse rate) in the treatment area. The method determines a vessel diameter, a real-time location and measurements of the bubble cloud, and estimates a dwell position and dwell time. A dynamic displayed image that is indicative of a progression of the laser catheter treatment is presented, and commands may be generated to modify the laser catheter parameters responsive to the estimated dwell position, the estimated dwell time, and a recommended treatment protocol.

公开(公告)号：WO2021126762A1

公开(公告)日：2021-06-24

申请号：PCT/US2020/064846

申请日：2020-12-14

Applicant: BOLT MEDICAL, INC.

Inventor： COOK, Christopher, A. ,  BACHER, Gerald, D. ,  SCHULTHEIS, Eric ,  MOSSAYEBI, Mina ,  XIE, Wenjie ,  LIU, Yu

IPC: A61B18/24 ,  A61B18/26 ,  A61B18/245 ,  A61B2018/0022 ,  A61B2018/00386 ,  A61B2018/00422 ,  A61B2018/2211 ,  A61B2018/263 ,  A61B2018/266 ,  G02B27/283 ,  G02B6/4213 ,  G02B6/4214

Abstract: A catheter system (100) for treating a vascular lesion (106 A) within or adjacent to a vessel wall (108 A) within a body (107) of a patient (109) includes a single light source (124) that generates light energy, a first light guide (122 A) and a second light guide (122A), and a multiplexer (128). The first light guide (122A) and the second light guide (122A) are each configured to selectively receive light energy from the light source (124). The multiplexer (128) receives the light energy from the light source (124) in the form of a source beam (124 A) and selectively directs the light energy from the light source (124) in the form of individual guide beams (124B) to each of the first light guide (122 A) and the second light guide (122A).

公开(公告)号：WO2021262404A1

公开(公告)日：2021-12-30

申请号：PCT/US2021/035342

申请日：2021-06-02

Applicant: GYRUS ACMI, INC. D/B/A OLYMPUS SURGICAL TECHNOLOGIES AMERICA

Inventor： SCHMITT, Jeffrey D.

IPC: A61B18/26 ,  A61B18/24 ,  A61B17/221 ,  A61B18/245 ,  A61B2017/0034 ,  A61B2018/00267 ,  A61B2018/00511 ,  A61B2018/00517 ,  A61B2018/00535 ,  A61B2018/208 ,  A61B2018/2211 ,  A61B2018/2272 ,  A61B2018/2277 ,  A61B2018/2294 ,  A61B2018/266

Abstract: A laser lithotripsy system to deliver laser energy from one or more laser sources to a stone (e.g., mobile calculus), the system including a capture portion, a first laser node and a second laser node. The capture portion configured to be movable from a stored state to a deployed state. In the deployed state, the capture portion is configured to at least partially surround the stone. The first laser node and the second laser node are coupled to the capture portion and are configured to deliver the laser energy to the stone, and the first laser node is spaced apart from the second laser node.

公开(公告)号：WO2021255013A1

公开(公告)日：2021-12-23

申请号：PCT/EP2021/066081

申请日：2021-06-15

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： ERKAMP, Ramon, Quido ,  CHEN, Alvin ,  BHARAT, Shyam ,  ZHENG, Mingxin ,  TOPOREK, Grzegorz, Andrzej ,  CEZO, James, David

IPC: A61B5/00 ,  A61B18/24 ,  A61B18/245 ,  A61B2018/00404 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00785 ,  A61B2018/00898 ,  A61B2018/00904 ,  A61B5/0095 ,  A61B5/6876

Abstract: Methods, Apparatuses, and Systems of operating a laser atherectomy system to perform an endoscopic atherectomy procedure within a vessel at a therapeutic region of an anatomical condition by use of an atherectomy laser device coupled to an ultrasound imaging probe. The atherectomy laser device operates to generate photoacoustic signals from a light source of the atherectomy laser device to for guidance within the vessel and to characterize tissue about the therapeutic region by delivery of pulsed wavelengths within the vessel, and to perform operations of tissue ablation directed to the anatomical condition. This enables guidance of the atherectomy laser device by feedback from the viewing of photoacoustic images based on photoacoustic signals generated the atherectomy laser device and created in response to changes in acoustic intensity due to changes of optical wavelength monitored by the ultrasound imaging probe.