公开(公告)号：WO2021119055A8

公开(公告)日：2021-06-17

申请号：PCT/US2020/063889

申请日：2020-12-09

Applicant: GENENTECH, INC. ,  F. HOFFMANN-LA ROCHE AG

Inventor： ELIAHU, Avi ,  ABERCROMBIE, Stuart

IPC: A61M11/00 ,  A61M15/00 ,  A61M11/002 ,  A61M11/003 ,  A61M15/0005 ,  A61M15/0008 ,  A61M15/0021 ,  A61M15/0028 ,  A61M15/003 ,  A61M15/0041 ,  A61M15/0086 ,  A61M2202/064 ,  A61M2206/14

Abstract: Exemplary dry powder inhaler devices may include a housing body having a medicine capsule recess therein, a pair of air inlets each fluidically connecting to the recess, and an outlet body coupled to the housing body. Each inlet may have a width no greater than 1.17 mm. The outlet body may have a channel fluidically connecting the recess to an opening and configured to allow a user to draw air through the opening, thereby allowing an airstream to be drawn through the air inlets, into the housing body recess where it causes the capsule to spin and eject its contents into the airstream, and through the outlet body channel and opening to deliver the substance into the user's lungs. Dry powder respirable drug blend formulations, methods of manufacturing the formulations and drug/device combinations are also provided.

公开(公告)号：WO2023278551A1

公开(公告)日：2023-01-05

申请号：PCT/US2022/035492

申请日：2022-06-29

Applicant: PNEUMA RESPIRATORY, INC.

Inventor： HEBRANK, John H. ,  CLEMENTS, Judson Sidney

IPC: A61M11/00 ,  A61M15/00 ,  A61M15/06 ,  A24F40/10 ,  A24F40/05 ,  A24F40/53 ,  A24F40/85 ,  A24F40/42 ,  A24F40/48 ,  A24F40/51 ,  A24F40/60 ,  A61M11/001 ,  A61M11/005 ,  A61M15/0005 ,  A61M15/0085 ,  A61M2205/332 ,  A61M2205/3331 ,  A61M2205/43 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/6018 ,  A61M2230/63

Abstract: A droplet delivery device with an ejector mechanism and fluid reservoir includes an accelerometer to determine and communicate optimized mixing of fluid in the reservoir for inhalation of droplets, such as into the lungs, from the droplet delivery device.