利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

17 条记录 (耗时 0.01 秒)

    PROCESS FOR MAKING MICROCRYSTALLINE DIMETHYL FUMARATE
    1.
    发明申请
    PROCESS FOR MAKING MICROCRYSTALLINE DIMETHYL FUMARATE 审中-公开
    制备微晶二甲基纤维素的方法

    公开(公告)号：WO2016001093A1

    公开(公告)日：2016-01-07

    申请号：PCT/EP2015/064564

    申请日：2015-06-26

    申请人： SYNTHON B.V.

    发明人： VYKLICKY, Libor

    IPC分类号： C07C67/08 ,  C07C67/52 ,  C07C69/70

    CPC分类号： C07C67/52 ,  C07C67/08 ,  C07C69/60

    摘要： The invention relates to a process for making a microcrystalline dimethyl fumarate comprising a step of providing a solution of dimethyl fumarate in methanol and combining the solution with water under precipitation of microcrystalline dimethyl fumarate.

    摘要翻译： 本发明涉及一种制备微晶富马酸二甲酯的方法，包括在富马酸二甲酯沉淀下将富马酸二甲酯溶于甲醇中并将该溶液与水混合的步骤。

    METHOD FOR CARRYING OUT A BALANCED REACTION
    4.
    发明申请
    METHOD FOR CARRYING OUT A BALANCED REACTION 审中-公开
    方法用于进行平衡反应

    公开(公告)号：WO99047484A1

    公开(公告)日：1999-09-23

    申请号：PCT/EP1999/001451

    申请日：1999-03-06

    IPC分类号： C07C41/50 ,  C07C67/08 ,  C07C43/303 ,  C07C43/305 ,  C07C69/36 ,  C07C69/60 ,  C07C69/675 ,  C07C69/70 ,  C07C69/704 ,  C07C69/708 ,  C07C69/716 ,  C07C69/72 ,  C07C69/80

    CPC分类号： C07C67/08 ,  C07B2200/07 ,  C07C41/56 ,  C07C2601/14 ,  C07C43/303 ,  C07C43/305

    摘要： The invention relates to a method for carrying out a balanced reaction, comprising the following steps: a) a low-boiling educt (E2) which is gaseous in the reaction conditions is guided through a separate, liquid, higher-boiling educt (E1) in a bubble reactor and b) unreacted educt (E2) is conveyed to a membrane module together with the product to be separated (P1), which is also in gaseous form, as feed. Said membrane module is located outside of the reactor and is suitable for vapour permeation. In said membrane module, P1 is separated off as permeate whilst E2 is recovered as retentate and returned to the reactor in a circuit until the desired quantity of educt (E1) has been converted into the target product. The method is characterised in that carbonyl compounds of formula (I) R -(CO)n1-(B)m-(CO)n2-R are used as (E1), B representing an optionally hydroxy- and/or carboxy-substituted alk(en)yl radical with 1 to 12 carbon atoms which is also optionally interrupted by an ether oxygen, a phenyl radical or a carbonyl group, R and R representing hydrogen or a hydroxyl or alkyl radical with 1 to 12 carbon atoms independently of each other or forming a saturated or unsaturated aliphatic C5 or C6 ring together with at least one carbonyl group, said ring being optionally substituted with C1-C4 alkyl and/or hydroxy and the sum of n1 and n2 being either 1 or 2 and m being 0 or 1, and in that aliphatic alcohols with 2 to 8 carbon atoms are used as (E2).

    摘要翻译： 执行Gleichegwichtsreaktion，其中（a）的低沸点，通过液体分离vorliegendes较重沸点离析物（E2）开始在鼓泡式反应器（E2）材料的反应条件下是气态的vorliegendes导出，（b）中提出的未反应的起始材料的方法（ E2）（连同也气态本分离的产品P1）供给作为进料的介质适合位于反应器膜组件，其中，（P1）被分离为渗透物，而（E2的外部气相渗透）回收作为渗余物，并且只要在反应器中的循环 返回到起始原料（E1）已被转移到目标产物的期望部分，其特征在于，作为（E1）羰基的式（I）化合物：R t <1> - （CO）N 1（B ）间 - （CO）N 2-R <2>：其中B为任选羟基 - 和/或羧基以及任选被醚氧取代unterbro rupted烷（烯）ylenrest具有1至12个碳原子，一个苯基或一个羰基，R <1>和R <2>独立地是氢，具有1至12个碳原子，或具有至少一个羰基一起羟基或烷基 形成饱和或不饱和的，任选C1-C4烷基和/或羟基取代的脂族C5-或C6-环，n1和n2为1或2，m是0或1，和具有E2的脂族醇的总和 从2至8个碳原子的使用。