专利检索 ipc:"C07K5/0205" 第 1 页

1.

发明申请
AURISTATIN-RELATED COMPOUNDS, CONJUGATED AURISTATIN-RELATED COMPOUNDS, AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：WO2021142029A1

公开(公告)日：2021-07-15

申请号：PCT/US2021/012364

申请日：2021-01-06

申请人： CYTOMX THERAPEUTICS, INC.

发明人： SCHLEYER, Siew , MENDELSOHN, Brian, A. , CHALLITA-EID, Pia , JACKSON, Dowdy , KEMBALL, Christopher

IPC分类号： C07K5/02 , C07K16/00 , A61K47/68 , A61K2039/505 , A61K47/6803 , A61K47/6869 , A61P35/00 , C07K16/3069 , C07K2317/33 , C07K2317/73 , C07K2317/92 , C07K2317/94 , C07K5/0205

摘要： The invention relates generally to novel compounds of the auristatin family, to novel linkers for coupling a payload to another molecule, such a target-binding molecule, to novel linker-toxin molecules, and to novel antibody molecules that allow controlled, site-specific conjugation.

2.

发明申请
ANTI-PSMA ANTIBODIES, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：WO2021142039A1

公开(公告)日：2021-07-15

申请号：PCT/US2021/012379

申请日：2021-01-06

申请人： CYTOMX THERAPEUTICS, INC.

发明人： HUBERT, Rene , KEMBALL, Christopher , CHALLITA-EID, Pia

IPC分类号： A61P35/00 , C07K16/30 , A61K39/395 , A61K2039/505 , A61K47/6803 , A61K47/6869 , C07K16/3069 , C07K2317/33 , C07K2317/73 , C07K2317/92 , C07K2317/94 , C07K5/0205

摘要： The invention relates generally to antibodies that bind PSMA, and methods of making and using these anti-PSMA antibodies in a variety of therapeutic, diagnostic and prophylactic indications.

3.

发明申请
LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME 审中-公开

公开(公告)号：WO2023280227A2

公开(公告)日：2023-01-12

申请号：PCT/CN2022/104174

申请日：2022-07-06

申请人： PROFOUNDBIO US CO.

发明人： SHANG, Xiao , LIU, Haidong , GAVRILYUK, Julia , ZHAO, Baiteng , HAN, Tae

IPC分类号： A61K47/65 , C07K5/083 , C07C211/00 , C07H5/06 , C07K5/09 , C07K5/02 , C07C237/08 , C07K5/0205 , C07K5/0808 , C07K5/0815

摘要： The present invention provides Polar units, Linker intermediates, Linkers, Drug-Linkers and Conjugates thereof

4.

发明申请
ANTI-SLC34A2 ANTIBODIES, ANTIBODY DRUG CONJUGATES, AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：WO2021142043A1

公开(公告)日：2021-07-15

申请号：PCT/US2021/012383

申请日：2021-01-06

申请人： CYTOMX THERAPEUTICS, INC.

发明人： JACKSON, Dowdy , SHOSTAK, Yuriy , KEMBALL, Christopher , CHALLITA-EID, Pia

IPC分类号： A61K47/68 , C07K16/30 , A61K39/395 , A61P35/00 , A61K2039/505 , A61K47/6803 , A61K47/6869 , C07K16/3069 , C07K2317/33 , C07K2317/73 , C07K2317/92 , C07K2317/94 , C07K5/0205

摘要： The invention relates generally to antibodies that bind SLC34A2, and methods of making and using these anti-SLC34A2 antibodies in a variety of therapeutic, diagnostic and prophylactic indications.