一种pH响应型水凝胶生物载体及应用

    公开(公告)号:WO2023077699A1

    公开(公告)日:2023-05-11

    申请号:PCT/CN2022/079518

    申请日:2022-03-07

    摘要: 本发明公开了一种pH响应型水凝胶生物载体,所述pH响应型水凝胶生物载体由透明质酸钠与甲基丙烯酸酐在光引发剂存在的条件下,用365nm紫外激光照射,透明质酸钠侧链上的羟基通过光致交联经过酯化作用聚合而成透明质酸的甲基丙烯酸酯衍生物。本发明还公开了一种装载有治疗性蛋白PDGF-BB的pH响应型水凝胶生物载体。本发明采用原位自由基聚合的方法合成,反应条件温和,对PDGF-BB的生物活性不会产生影响;把PDGF-BB包裹在水凝胶内,避免暴露在酶环境中,提高了PDGF-BB生物活性的稳定性。

    ポジ型感光性樹脂組成物
    2.
    发明申请

    公开(公告)号:WO2023007972A1

    公开(公告)日:2023-02-02

    申请号:PCT/JP2022/023848

    申请日:2022-06-14

    摘要: 【課題】 新規なポジ型感光性樹脂組成物を提供する。 【解決手段】 下記(A)成分、下記(B)成分、下記(C)成分及び下記(D)成分、又は下記(A´)成分、下記(B)成分、下記(C)成分、下記(D)成分及び下記(E)成分を含み、さらに溶剤を含むポジ型感光性樹脂組成物。 (A)成分:酸架橋性基を有するアルカリ可溶性樹脂 (A´)成分:酸架橋性基を有さないアルカリ可溶性樹脂 (B)成分:キノンジアジド化合物 (C)成分:光酸発生剤 (D)成分:PED安定性向上剤 (E)成分:酸架橋性基を分子中に少なくとも2つ有する化合物

    PHOTOCURABLE RESIN COMPOSITION AND PLASTIC SHEET
    7.
    发明申请
    PHOTOCURABLE RESIN COMPOSITION AND PLASTIC SHEET 审中-公开
    可光致树脂组合物和塑料片

    公开(公告)号:WO01029138A1

    公开(公告)日:2001-04-26

    申请号:PCT/NL2000/000744

    申请日:2000-10-16

    摘要: A photocurable resin composition suitable for forming a cured film on a plastic substrate, wherein the cured film obtainable by photocuring the photocurable resin composition has a refractive index between 1,56 and 1,65 and a plastic sheet coated by the cured coating of the photocurable resin composition are provided. A stain-proof and damage-proof plastic sheet without interference fringes can be obtained by using the composition. Such a plastic sheet is useful as an exterior material for ornamental panels and furniture, and as a backlight optical material for liquid display devices as a plastic lens sheet exhibiting high luminance without change in color.

    摘要翻译: 一种适用于在塑料基材上形成固化膜的光固化性树脂组合物,其中通过光固化可光固化树脂组合物获得的固化膜的折射率为156至165,以及通过光固化涂层涂覆的塑料片 提供树脂组合物。 通过使用该组合物可以获得不含干涉条纹的防污染和防损伤塑料片。 这样的塑料片可用作装饰面板和家具的外部材料,并且作为用于液晶显示装置的背光源材料,作为展现高亮度且不变色的塑料透镜片是有用的。

    CERAMER COMPOSITION AND COMPOSITE COMPRISING FREE RADICALLY CURABLE FLUOROCHEMICAL COMPONENT
    8.
    发明申请
    CERAMER COMPOSITION AND COMPOSITE COMPRISING FREE RADICALLY CURABLE FLUOROCHEMICAL COMPONENT 审中-公开
    陶瓷组合物和复合材料包含免费的可光化的化学成分

    公开(公告)号:WO00050517A1

    公开(公告)日:2000-08-31

    申请号:PCT/US2000/001071

    申请日:2000-01-18

    摘要: A ceramer composition is provided that comprises a plurality of colloidal inorganic oxide particles and a free-radically curable binder precursor. The free-radically curable binder precursor comprises a fluorochemical component that further comprises at least two free-radically curable moieties and at least one fluorinated moiety. By virtue of the inclusion of the fluorochemical component, the ceramer compositions of the present invention can be used to provide ceramer composites and ceramer composite structures with excellent stain, oil and/or water repellency characteristics as well as a high level of abrasion resistance and hardness.

    摘要翻译: 提供了一种陶瓷单体组合物,其包含多种胶态无机氧化物颗粒和可自由基固化的粘合剂前体。 可自由基固化的粘合剂前体包含进一步包含至少两个可自由基固化部分和至少一个氟化部分的含氟化合物组分。 由于含有含氟成分,本发明的陶瓷单体组合物可用于提供具有优异的耐污染性,油和/或拒水性以及高耐磨性和硬度的陶瓷复合材料和陶瓷复合材料结构 。

    ACRYLIC PREMIX, ACRYLIC ARTIFICIAL MARBLE, AND PROCESS FOR PRODUCING THE SAME
    9.
    发明申请
    ACRYLIC PREMIX, ACRYLIC ARTIFICIAL MARBLE, AND PROCESS FOR PRODUCING THE SAME 审中-公开
    丙烯酸丙烯酸酯,丙烯酸人造大理石及其制造方法

    公开(公告)号:WO99055633A1

    公开(公告)日:1999-11-04

    申请号:PCT/JP1999/002225

    申请日:1999-04-27

    摘要: An acrylic premix comprising (A) 10 to 90 wt.% acrylic resin composition comprising (a1) a monofunctional acrylic monomer, (a2) at least one of a polyfunctional acrylic monomers represented by general formulae (I to IV), and (b) an acrylic polymer, (B) 10 to 90 wt.% inorganic filler, and (C) a hardener in an amount of 0.01 to 10 parts by weight per 100 parts by weight of the sum of the components (A) and (B); and an acrylic artificial marble made using the premix and a process for producing the marble. The premix is useful for providing acrylic SMC or BMC which are satisfactory in high-temperature moldability, moldability, suitability for thickening, and storage stability. In (I), R1 is -H or CH3; and k is 3 to 30. In (II), l and m each is 0 to 25, provided that l+m is 2 to 25. In (III), n is 2 to 25. In (IV), R2 to R5 each is C1-10 alkylene; and p, q, and r each is 0 to 10, provided that p+q+r is 2 to 25.

    摘要翻译: 一种丙烯酸类预混物,其包含(A)10至90重量%的丙烯酸树脂组合物,其包含(a1)单官能丙烯酸类单体,(a2)由通式(I至IV)和(b)表示的多官能丙烯酸单体中的至少一种, 丙烯酸类聚合物,(B)10〜90重量%的无机填料,和(C)每100重量份组分(A)和(B)之和为0.01〜10重量份的固化剂, ; 和使用该预混物制成的丙烯酸人造大理石和制造大理石的方法。 预混物可用于提供在高温成型性,成型性,适用于增稠和储存稳定性方面令人满意的丙烯酸SMC或BMC。 在(I)中,R 1为-H或CH 3; (II)中,l和m各自为0〜25,条件是l + m为2〜25。在(III)中,n为2〜25。(Ⅳ)中,R2〜R5 各为C1-10亚烷基; p,q,r各自为0〜10,条件是p + q + r为2〜25。