The invention discloses a clam-flavor seasoning soup block and a preparation method thereof. The clam-flavor seasoning soup block comprises a main seasoning and palm oil, wherein the main seasoning comprises 70%-90% of clam-flavor solid powder and the balance of minced clam meat; 15g-30g of palm oil is added when 100g of clam-flavor solid powder is added. The preparation method comprises the following steps: firstly preparing clam pulp, then freeze-drying partial clam pulp to obtain the minced clam meat, carrying out biological enzymolysis on the residual clam pulp, concentrating and freeze-drying supernate after the enzymolysis to obtain enzymolysis freeze-dried powder, carrying out Maillard reaction on precipitates to obtain Maillard reaction powder, and mixing the Maillard reaction powder with the enzymolysis freeze-dried powder; preparing the clam-flavor solid powder according to the formula, and uniformly stirring and pressing the clam-flavor solid powder, the minced clam meat and the palm oil, so as to obtain the clam-flavor seasoning soup block. The clam-flavor seasoning soup block can resist high temperature cooking, is suitable for preparing multiple kinds of soup. According to the preparation method, biological enzymolysis is combined with the Maillard reaction, so that fresh flavor components in the clam are adequately extracted; the clam-flavor seasoning soup block is rich in protein and amino acid, and flavors of products can be improved.