The invention discloses a high/low-speed bus communication method. The method comprises write operation and read operation of a high-speed bus. The write operation comprises the following steps: performing address decoding on high-speed parallel data; allocating a write operation token to a first storage unit, and writing the high-speed parallel data into the first storage unit; converting the high-speed parallel data into low-speed serial data and writing the low-speed serial data into a low-speed bus; and releasing the write operation token. The read operation comprises the following steps: allocating a write operation token to a second storage unit; converting corresponding low-speed serial data into high-speed parallel data, writing the high-speed parallel data into the second storage unit, and writing the high-speed parallel data into the high-speed bus; and releasing a read operation token. The invention also discloses a communication device. The communication device comprises a control logical module, a token partition module, an address decoding module, a series-to-parallel conversion module, a parallel-to-series conversion module and a data buffering module. Both the method and device have the advantages of time division multiplexing, high communication efficiency, high instantaneity and high stability.