The invention relates to a reinforcement configuration memory array applicable to an FPGA (Field Programmable Gate Array) for space navigation and a configuration method of the reinforcement configuration memory array, wherein the configuration memory array uses DICEs (Double Interlocked Storage Cells) for realizing single particle reinforcement of the configuration memory array; and the influence of single particles on the configuration memory array is reduced. The configuration method is characterized in that before the configuration memory array is electrified, all configuration memory units are in a 0-write state through a column address decoding circuit and a frame data register; and during electrification, all initial states of all DICEs after the electrification are 0 due to the inductive effect of external work conditions. The logic conflict of an FPGA interconnection matrix after the electrification due to the non-determined state of the configuration memory units is avoided, so that the problem of electrification surge current of the FPGA is effectively solved; the design difficulty of a system using the FPGA is reduced; and the work reliability of the FPGA for space navigation is improved.