A variable valve mechanism of an internal combustion engine includes a plurality of swing members and a variable device that displaces a control shaft to displace a plurality of slider gears of the swing members at a time, thereby changing valve lifts of the plurality of swing members at a time by meshing of helical splines. The swing members include a first swing member for a predetermined cylinder of a plurality of cylinders and a second swing member for a cylinder other than the predetermined cylinder, and a helix angle of the helical splines varies between the first and the second swing members. The variable device displaces the control shaft to a predetermined normal position to perform a normal operation, and displaces the control shaft to a predetermined cylinder cutoff position to perform a cylinder cutoff operation in which the second swing member does not drive a valve.