The invention discloses a motor interlocking locating device for a high-acceleration centrifugal machine. A locating device is mounted on a motor rear end cover and comprises a switch used for controlling starting and shutdown of a motor and a body part structure. The switch is a touch switch, and the switching signal output end of the switch is connected with the signal input end of the motor. When the body part structure stretches forwards, the switch is touched, the motor cannot enter a work state under a control command, and the forward-stretching part of the body part structure cooperatesto lock a motor shaft. When the body part structure retracts, the switch is not touched, the motor can enter the work state under a control command, and the forward-stretching part of the body part structure is not in contact with the motor shaft. The motor interlocking locating device is compact in structure and small in mass, and increments caused to rotating arm loads and system rotational inertia are small; and meanwhile, the motor is locked through switching signal changes, then interlocking locating of the motor is achieved, motor accidental rotating is avoided, and the motor interlocking locating device is suitable for motor locating in the high-centrifugal-acceleration centrifugal machine