发明公开
- 专利标题： ANTIBODIES AGAINST OX40 AND USES THEREOF
- 专利标题（中）： 抗OX40的抗体及其用途
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申请号： EP16729129.3申请日： 2016-05-26
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公开(公告)号： EP3303396A1公开(公告)日： 2018-04-11
- 发明人: CAI, Zhehong , CHAKRABORTY, Indrani , GARCIA, Marie-Michelle, Navarro , KEMPE, Thomas, D. , KORMAN, Alan, J. , KOZHICH, Alexander, T. , LEMAR, Hadia , MAURER, Mark , MILBURN, Christina, Maria , QUIGLEY, Michael , RODRIGUEZ, Maria , SHAO, Xiang , SRINIVASAN, Mohan , STEVENS, Brenda, L. , THUDIUM, Kent , WONG, Susan, Chien-Szu , GOKEMEIJER, Jochem , WANG, Xi-Tao , CHANG, Han , HUANG, Christine , JURE-KUNKEL, Maria , YANG, Zheng , FENG, Yan , GUIRNALDA, Patrick , LONBERG, Nils , BARNHART, Bryan C. , YAMNIUK, Aaron P. , HENNING, Karla A. , HAN, Michelle Minhua , LEI, Ming , SCHWEIZER, Liang , HATCHER, Sandra V. , RAJPAL, Arvind , AANUR, Praveen , SELBY, Mark J.
- 申请人： Bristol-Myers Squibb Company
- 申请人地址： Route 206 and Province Line Road Princeton, NJ 08543 US
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： Route 206 and Province Line Road Princeton, NJ 08543 US
- 代理机构： Reitstötter Kinzebach
- 优先权： US201562168377P 20150529; US201562239574P 20151009; US201562264691P 20151208; US201662327140P 20160425; US201662333556P 20160509
- 国际公布： WO2016196228 20161208
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395 ; A61P35/00
摘要：
Provided herein are antibodies, or antigen binding portions thereof, that bind to OX40. Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.
公开/授权文献
- EP3303396B1 ANTIBODIES AGAINST OX40 AND USES THEREOF 公开/授权日：2022-11-23
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