- 专利标题: Optimized Fc variants and methods for their generation
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申请号: US15167832申请日: 2016-05-27
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公开(公告)号: US10184000B2公开(公告)日: 2019-01-22
- 发明人: Gregory Alan Lazar , Arthur J. Chirino , Wei Dang , John Desjarlais , Stephen K. Doberstein , Robert J. Hayes , Sher Bahadur Karki , Omid Vafa
- 申请人: Xencor, Inc.
- 申请人地址: US CA Monrovia
- 专利权人: Xencor, Inc.
- 当前专利权人: Xencor, Inc.
- 当前专利权人地址: US CA Monrovia
- 代理机构: Morgan, Lewis & Bockius, LLP
- 代理商 Robin M. Silva; Kun Ma
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C12N15/00 ; C12N5/02 ; C12P21/06 ; C07K16/00 ; C07K16/28 ; C07K16/32 ; A61K39/395 ; C07K16/22 ; C07K16/42 ; C40B30/02 ; G06F19/16 ; G06F19/22 ; C12P21/00 ; G06F19/12 ; A61K39/00
摘要:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
公开/授权文献
- US20160347825A1 OPTIMIZED Fc VARIANTS AND METHODS FOR THEIR GENERATION 公开/授权日:2016-12-01
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