An LED-based lighting fixture sets or adjusts a parameter of a drive signal that is used to drive its LEDs to be more compatible with the camera system; the camera system sets or adjusts an image capture parameter to be more compatible with the LED-based lighting fixture, or a combination thereof. The drive signal may be a PWM signal with a variable PWM frequency and/or duty cycle, a variable DC signal, or any combination thereof. The parameter of the drive signal that may be set or adjusted includes, but is not limited to, a PWM period, PWM frequency, PWM duty cycle, amplitude of the active and inactive portions of the PWM signal, and the like. The image capture parameter that may be adjusted includes, but is not limited to, frame rate, frame period, integration time, gain, shutter type (i.e. rolling shutter, global shutter, etc.), and the like.