The invention relates to an intertwined multilayer primer/fluoropolymer coating on the glass substrate. The final coating has excellent wet adhesion to glass, good weathering, durability, chalking resistance, chemical resistance, and dirt pickup resistance. The coating is an environmentally friendly aqueous, fluoropolymer coating composition. The coating process involves applying a polyurethane primer to the glass substrate, and partially, but not completely crosslinking this primer coating. An aqueous hydroxyl-functional fluoropolymer coating is then applied to the partially cross-linked primer coating, and the coating allowed to fully cure. The invention also relates to the intertwined multilayer primer/fluoropolymer coating on the glass substrate. The final coating has excellent wet adhesion to glass, good weathering, durability, chalking resistance, chemical resistance, and dirt pickup resistance.