Invention Grant
- Patent Title: Biomolecule sequencing devices, systems and methods
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Application No.: US15448317Application Date: 2017-03-02
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Publication No.: US10557167B2Publication Date: 2020-02-11
- Inventor: Tomoji Kawai , Masateru Taniguchi , Takahito Ohshiro , Mark Oldham , Eric Nordman
- Applicant: Quantum Biosystems Inc.
- Applicant Address: JP Tokyo
- Assignee: QUANTUM BIOSYSTEMS INC.
- Current Assignee: QUANTUM BIOSYSTEMS INC.
- Current Assignee Address: JP Tokyo
- Agency: Wilson Sonsini Goodrich & Rosati
- Priority: JP2013-193498 20130918; JP2013-197443 20130924
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G06F19/22 ; G01N27/04 ; C12Q1/6869 ; G16B30/00

Abstract:
Devices, systems and methods for sequencing protein samples are provided. In some examples, currents generated when a monomer passes through between electrodes of a nanogap electrode pair are measured for each of several different distances, so that monomers are identified when compared to a reference physical quantity of a known monomer, which may be obtained from a current measured with a similar inter-electrode distance(s) at which each of plural kinds of monomers are identifiable and ordered with predetermined accuracy and based on a detected physical quantity obtained from a tunneling current, which may be further normalized by the use of one or more reference substances.
Public/Granted literature
- US20180023132A1 BIOMOLECULE SEQUENCING DEVICES, SYSTEMS AND METHODS Public/Granted day:2018-01-25
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