中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

13 records (took 0.016 seconds)

    NANO-GAP ELECTRODE PAIR AND METHOD OF MANUFACTURING SAME
    1.
    发明申请
    NANO-GAP ELECTRODE PAIR AND METHOD OF MANUFACTURING SAME 审中-公开

    公开(公告)号：US20190310240A1

    公开(公告)日：2019-10-10

    申请号：US16178924

    申请日：2018-11-02

    Applicant: Quantum Biosystems Inc.

    Inventor： Shuji Ikeda ,  Mark Oldham ,  Eric S. Nordman

    IPC: G01N33/487 ,  G01N27/327 ,  C23C16/455 ,  G01N27/447

    Abstract: A system for detecting a biomolecule comprises a nano-gap electrode device including a first electrode and a second electrode adjacent to the first electrode. The first electrode can be separated from the second electrode by a nano-gap that is dimensioned to permit the biomolecule to flow through the nano-gap. The nano-gap can have at least a first gap region and a second gap region. The second gap region can be oriented at an angle that is greater than zero degrees with respect to a plane having the first gap region. The system can further include an electrical circuit coupled to the nano-gap electrode device. The electrical circuit can receive electrical signals from the first electrode and the second electrode upon the flow of the biomolecule through the nano-gap.

    BIOMOLECULE SEQUENCING DEVICES, SYSTEMS AND METHODS
    2.
    发明申请
    BIOMOLECULE SEQUENCING DEVICES, SYSTEMS AND METHODS 审中-公开

    公开(公告)号：US20180023132A1

    公开(公告)日：2018-01-25

    申请号：US15448317

    申请日：2017-03-02

    Applicant: Quantum Biosystems Inc.

    Inventor： Tomoji Kawai ,  Masateru Taniguchi ,  Takahito Ohshiro ,  Mark Oldham ,  Eric Nordman

    IPC: C12Q1/68 ,  G06F19/22 ,  G01N27/04

    Abstract: Devices, systems and methods for sequencing protein samples are provided. In some examples, currents generated when a monomer passes through between electrodes of a nanogap electrode pair are measured for each of several different distances, so that monomers are identified when compared to a reference physical quantity of a known monomer, which may be obtained from a current measured with a similar inter-electrode distance(s) at which each of plural kinds of monomers are identifiable and ordered with predetermined accuracy and based on a detected physical quantity obtained from a tunneling current, which may be further normalized by the use of one or more reference substances.

    Biomolecule sequencing devices, systems and methods
    5.
    发明授权
    Biomolecule sequencing devices, systems and methods 有权

    公开(公告)号：US10557167B2

    公开(公告)日：2020-02-11

    申请号：US15448317

    申请日：2017-03-02

    Applicant: Quantum Biosystems Inc.

    Inventor： Tomoji Kawai ,  Masateru Taniguchi ,  Takahito Ohshiro ,  Mark Oldham ,  Eric Nordman

    IPC: C12Q1/68 ,  G06F19/22 ,  G01N27/04 ,  C12Q1/6869 ,  G16B30/00

    Abstract: Devices, systems and methods for sequencing protein samples are provided. In some examples, currents generated when a monomer passes through between electrodes of a nanogap electrode pair are measured for each of several different distances, so that monomers are identified when compared to a reference physical quantity of a known monomer, which may be obtained from a current measured with a similar inter-electrode distance(s) at which each of plural kinds of monomers are identifiable and ordered with predetermined accuracy and based on a detected physical quantity obtained from a tunneling current, which may be further normalized by the use of one or more reference substances.

    Nano-gap electrode pair and method of manufacturing same
    6.
    发明授权
    Nano-gap electrode pair and method of manufacturing same 有权

    公开(公告)号：US10466228B2

    公开(公告)日：2019-11-05

    申请号：US16178924

    申请日：2018-11-02

    Applicant: Quantum Biosystems Inc.

    Inventor： Shuji Ikeda ,  Mark Oldham ,  Eric S. Nordman

    IPC: G01N27/447 ,  G01N33/487 ,  C23C16/455 ,  G01N27/327

    Abstract: A system for detecting a biomolecule comprises a nano-gap electrode device including a first electrode and a second electrode adjacent to the first electrode. The first electrode can be separated from the second electrode by a nano-gap that is dimensioned to permit the biomolecule to flow through the nano-gap. The nano-gap can have at least a first gap region and a second gap region. The second gap region can be oriented at an angle that is greater than zero degrees with respect to a plane having the first gap region. The system can further include an electrical circuit coupled to the nano-gap electrode device. The electrical circuit can receive electrical signals from the first electrode and the second electrode upon the flow of the biomolecule through the nano-gap.

    SYSTEMS AND METHODS FOR BIOLOGICAL DATA MANAGEMENT
    7.
    发明申请
    SYSTEMS AND METHODS FOR BIOLOGICAL DATA MANAGEMENT 审中-公开

    公开(公告)号：US20190304571A1

    公开(公告)日：2019-10-03

    申请号：US16156755

    申请日：2018-10-10

    Applicant: Quantum Biosystems Inc.

    Inventor： Masoud Vakili ,  Kurt Christofferson ,  Mark Oldham

    IPC: G16B50/30 ,  G16B50/40 ,  G06F17/18

    Abstract: Systems and methods for biological data management may preserve alternative interpretations of data and may implement multi-level encryption and privacy management. Systems and methods for biological data management may include a cell-level architecture, a bank-and-bloc-level architecture, and/or a multi-tiered architecture. Systems and methods for biological data management may incorporate definitions, rules, and directives and/or employ a two-dimensional or three-dimensional data structure.

    NANO-GAP ELECTRODE PAIR AND METHOD OF MANUFACTURING SAME
    9.
    发明申请
    NANO-GAP ELECTRODE PAIR AND METHOD OF MANUFACTURING SAME 审中-公开
    纳米GAP电极对及其制造方法

    公开(公告)号：US20160320364A1

    公开(公告)日：2016-11-03

    申请号：US15098147

    申请日：2016-04-13

    Applicant: Quantum Biosystems Inc.

    Inventor： Shuji Ikeda ,  Mark Oldham ,  Eric S. Nordman

    IPC: G01N33/487 ,  C23C16/455 ,  G01N27/447

    CPC classification number: G01N33/48721 ,  C23C16/45525 ,  G01N27/44791

    Abstract: A system for detecting a biomolecule comprises a nano-gap electrode device including a first electrode and a second electrode adjacent to the first electrode. The first electrode can be separated from the second electrode by a nano-gap that is dimensioned to permit the biomolecule to flow through the nano-gap. The nano-gap can have at least a first gap region and a second gap region. The second gap region can be oriented at an angle that is greater than zero degrees with respect to a plane having the first gap region. The system can further include an electrical circuit coupled to the nano-gap electrode device. The electrical circuit can receive electrical signals from the first electrode and the second electrode upon the flow of the biomolecule through the nano-gap.

    Abstract translation: 用于检测生物分子的系统包括纳米间隙电极装置，其包括与第一电极相邻的第一电极和第二电极。 第一电极可以通过纳米间隙与第二电极分离，其尺寸被设计成允许生物分子流过纳米间隙。 纳米间隙可以具有至少第一间隙区域和第二间隙区域。 第二间隙区域可相对于具有第一间隙区域的平面以大于零度的角度定向。 该系统还可以包括耦合到纳米间隙电极器件的电路。 当生物分子流过纳米间隙时，电路可以接收来自第一电极和第二电极的电信号。

Patent Agency Ranking