- 专利标题： Culture method for stable proliferation of pluripotent stem cell while maintaining undifferentiated state
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申请号： US16242463申请日： 2019-01-08
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公开(公告)号： US10662411B2公开(公告)日： 2020-05-26
- 发明人: Sho Senda , Tomomi Yoshida , Satoru Okamoto , Yoko Kuriyama , Manabu Kitazawa , Ikue Harata , Nao Sugimoto
- 申请人： AJINOMOTO CO., INC.
- 申请人地址： JP Tokyo
- 专利权人： AJINOMOTO CO., INC.
- 当前专利权人： AJINOMOTO CO., INC.
- 当前专利权人地址： JP Tokyo
- 代理机构： Oblon, McClelland, Maier & Neustadt, L.L.P.
- 优先权： com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2af2db9b
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/02 ; C12N5/074 ; C12N5/0735
摘要：
Cultivating a pluripotent stem cell in a medium comprising at least one member selected from the group consisting of ethanolamine, an ethanolamine analog, and a pharmaceutically acceptable salt thereof, and which is substantially free of β-mercaptoethanol or contains β-mercaptoethanol at a concentration of not more than 9 μM, and the like, is effective for the proliferation of a pluripotent stem cell while maintaining an undifferentiated state.
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