- 专利标题: Enzymatic conjugation of antibodies
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申请号: US15702586申请日: 2017-09-12
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公开(公告)号: US10675359B2公开(公告)日: 2020-06-09
- 发明人: Patrick Dennler , Delphine Bregeon , Laurent Gauthier , François Romagné , Christian Belmant , Eliane Fischer , Roger Schibli
- 申请人: Innate Pharma , Paul Scherrer Institut
- 申请人地址: FR Marseilles CH Villigen
- 专利权人: Innate Pharma,Paul Scherrer Institut
- 当前专利权人: Innate Pharma,Paul Scherrer Institut
- 当前专利权人地址: FR Marseilles CH Villigen
- 代理机构: Knobbe, Martens, Olson & Bear, LLP
- 主分类号: A61K47/68
- IPC分类号: A61K47/68 ; C07K16/00 ; A61K47/60 ; C07C217/08 ; C07C223/02 ; C07C229/26 ; C07C233/62 ; C07C247/04 ; C07C323/12 ; C07C323/60 ; C07D225/08 ; C07D257/08 ; C07D277/06 ; C07F9/50 ; C07K19/00 ; C12N9/10 ; C12P21/00 ; G01N33/68
摘要:
The present application relates to methods for the functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
公开/授权文献
- US20180193476A1 ENZYMATIC CONJUGATION OF ANTIBODIES 公开/授权日:2018-07-12
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