Invention Grant
![Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections](/docs/US/2020-06-23/US10689399B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections
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Application No.: US16017371Application Date: 2018-06-25
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Publication No.: US10689399B2Publication Date: 2020-06-23
- Inventor: Elizabeth M. Bacon , Zhenhong R. Cai , Xiaowu Chen , Jeromy J. Cottell , Manoj C. Desai , Mingzhe Ji , Haolun Jin , Scott E. Lazerwith , Michael R. Mish , Philip Anthony Morganelli , Hyung-Jung Pyun , James G. Taylor , Teresa Alejandra Trejo Martin
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D413/14 ; C07D498/14 ; A61K31/537 ; C07D471/22 ; A61K31/529 ; A61K31/551 ; A61K31/498 ; C07D471/18 ; A61K45/06 ; C07D498/18 ; C07D487/14 ; A61K31/553
![Substituted 3,4,5,6,8,10,14,14a-octahydro-2h-2,6-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazocines and methods for treating viral infections](/abs-image/US/2020/06/23/US10689399B2/abs.jpg.150x150.jpg)
Abstract:
Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): including stereoisomers and pharmaceutically acceptable salts thereof, wherein R1, X, W, Y1, Y2, Z1, and Z4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
Public/Granted literature
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