Invention Grant
- Patent Title: Biaryl amide compounds as kinase inhibitors
-
Application No.: US16274165Application Date: 2019-02-12
-
Publication No.: US10709712B2Publication Date: 2020-07-14
- Inventor: Robert John Aversa , Paul Andrew Barsanti , Matthew T. Burger , Michael Patrick Dillon , Alan Dipesa , Cheng Hu , Yan Lou , Gisele A. Nishiguchi , Yue Pan , Valery Rostislavovich Polyakov , Savithri Ramurthy , Alice C. Rico , Lina Quattrocchio Setti , Aaron Smith , Sharadha Subramanian , Benjamin R. Taft , Huw Roland Tanner , Lifeng Wan , Naeem Yusuff
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Scott W. Reid
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; C07D413/04 ; A61K31/541 ; A61K45/06 ; C07D213/74 ; C07D237/20 ; C07D239/42 ; C07D239/47 ; C07D239/48 ; C07D277/42 ; C07D401/12 ; C07D403/04 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D493/10 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; C07D213/75 ; C07D233/88 ; C07D401/04 ; C07D405/04 ; C07D405/12 ; C07D241/20 ; C07D471/04 ; C07D487/04 ; C07D263/58 ; C07D491/107 ; C07D493/04 ; C07D495/04 ; C07D498/08 ; C07D513/04 ; A61K31/5375 ; C07D213/81 ; C07D213/82 ; C07D213/84 ; C07D237/22 ; C07D409/14 ; C07D491/048 ; A61K31/444 ; A61K31/501 ; C07B59/00 ; C07D237/24 ; C07D491/04 ; C07D491/08
Abstract:
The present invention provides compounds of Formula (I) as described herein, and salts thereof, and therapeutic uses of these compounds for treatment of disorders associated with Raf kinase activity. The invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds and a therapeutic co-agent.
Public/Granted literature
- US20190175606A1 BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS Public/Granted day:2019-06-13
Information query
IPC分类:
