Invention Grant
- Patent Title: Modified alginates for anti-fibrotic materials and applications
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Application No.: US15341110Application Date: 2016-11-02
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Publication No.: US10709818B2Publication Date: 2020-07-14
- Inventor: Arturo J. Vegas , Joshua C. Doloff , Omid Veiseh , Minglin Ma , Robert S. Langer , Daniel G. Anderson
- Applicant: Massachusetts Institute of Technology , The Children's Medical Center Corporation
- Applicant Address: US MA Cambridge US MA Boston
- Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY,THE CHILDREN'S MEDICAL CENTER CORPORATION
- Current Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY,THE CHILDREN'S MEDICAL CENTER CORPORATION
- Current Assignee Address: US MA Cambridge US MA Boston
- Agency: Pabst Patent Group LLP
- Main IPC: A61L29/08
- IPC: A61L29/08 ; A61K47/36 ; A61K9/48 ; A61K35/39 ; C08B37/00 ; A61K9/00 ; A61K9/50 ; A61L31/10 ; A61L33/08 ; C07D487/04 ; C12N5/00 ; C12N5/071
Abstract:
Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.
Public/Granted literature
- US20170226232A1 MODIFIED ALGINATES FOR ANTI-FIBROTIC MATERIALS AND APPLICATIONS Public/Granted day:2017-08-10
Information query
