- Patent Title: Surface treatment by water-soluble polymers and lipids/liposomes
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Application No.: US15319005Application Date: 2015-06-15
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Publication No.: US10940111B2Publication Date: 2021-03-09
- Inventor: Jacob Klein , Ronit Goldberg , Jasmine Seror , Weifeng Lin , Reut Mashiach
- Applicant: Yeda Research and Development Co. Ltd.
- Applicant Address: IL Rehovot
- Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee: Yeda Research and Development Co. Ltd.
- Current Assignee Address: IL Rehovot
- International Application: PCT/IL2015/050606 WO 20150615
- International Announcement: WO2015/193888 WO 20151223
- Main IPC: A61K9/127
- IPC: A61K9/127 ; A61K9/00 ; A61K47/32 ; A61K47/10 ; A61K47/36 ; A61K9/08 ; A61K31/728 ; A61K31/77 ; A61K31/79 ; B65D35/00 ; B65D75/36

Abstract:
A method of reducing a friction coefficient of a surface is disclosed herein, comprising attaching a water-soluble polymer to the surface, and contacting the water-soluble polymer with liposomes, thereby coating the surface with an amphiphilic lipid. Further disclosed herein are solutions comprising a water-soluble polymer attachable to the surface, liposomes, and an aqueous carrier, for reducing a friction coefficient of a surface, and methods utilizing same. Articles of manufacture comprising a substrate coated by a water-soluble polymer which is coated by an amphiphilic lipid are also described, as are uses and methods for treating a synovial joint disorder associated with increased articular friction.
Public/Granted literature
- US20170128365A1 SURFACE TREATMENT BY WATER-SOLUBLE POLYMERS AND LIPIDS/LIPOSOMES Public/Granted day:2017-05-11
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