Invention Grant
- Patent Title: Open-top microfluidic device with structural anchors
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Application No.: US15781370Application Date: 2016-12-02
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Publication No.: US10961496B2Publication Date: 2021-03-30
- Inventor: Daniel Levner , Christopher David Hinojosa , Norman Wen , Antonio Varone , Justin Nguyen , Lina Williamson , S. Jordan Kerns , Catherine Karalis , Geraldine Hamilton , Carol Lucchesi
- Applicant: EMULATE, INC.
- Applicant Address: US MA Boston
- Assignee: EMULATE, INC.
- Current Assignee: EMULATE, INC.
- Current Assignee Address: US MA Boston
- Agency: Medlen & Carroll, LLP
- International Application: PCT/US2016/064814 WO 20161202
- International Announcement: WO2017/096297 WO 20170608
- Main IPC: C12M1/42
- IPC: C12M1/42 ; C12M3/06 ; C12M1/12 ; G01N33/50 ; G01N33/543 ; C12M1/00 ; C12N5/0793 ; C12N5/079 ; C12N5/071 ; C12N5/077
Abstract:
A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.
Public/Granted literature
- US20180320125A1 OPEN-TOP MICROFLUIDIC DEVICE WITH STRUCTURAL ANCHORS Public/Granted day:2018-11-08
Information query
