Invention Grant
- Patent Title: Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
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Application No.: US16819325Application Date: 2020-03-16
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Publication No.: US10995085B2Publication Date: 2021-05-04
- Inventor: Yongxin Han , Abdelghani Achab , Yongqi Deng , Xavier Fradera , Craig Gibeau , Brett A. Hopkins , Derun Li , Kun Liu , Meredeth A. McGowan , Nunzio Sciammetta , David Sloman , Catherine White , Hongjun Zhang , Hua Zhou
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Yong Zhao; Anna L. Cocuzzo
- Main IPC: C07D405/10
- IPC: C07D405/10 ; A61K31/4523 ; A61K45/06 ; C07D471/04 ; A61K31/437 ; A61K31/506 ; A61K31/4155 ; C07D305/08 ; A61K31/337 ; C07D417/10 ; A61K31/427 ; A61K31/41 ; A61K31/4245 ; A61K31/4184 ; C07D405/14 ; A61K31/444 ; A61K31/513 ; C07D413/04 ; C07D401/04 ; C07D213/56 ; A61K31/4418 ; C07D417/14 ; A61K31/501 ; C07D241/12 ; A61K31/4965 ; A61K31/4427 ; C07D263/32 ; A61P37/00 ; C07D231/12 ; A61P35/00 ; C07D413/10 ; C07D401/12 ; C07D405/04 ; A61P31/00 ; C07D209/46 ; C07D413/14
Abstract:
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.
Public/Granted literature
- US20200216425A1 NOVEL SUBSTITUTED BIARYL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS Public/Granted day:2020-07-09
Information query
