A method of image processing includes obtaining depth information respectively corresponding to one or more objects in an image frame captured by an imaging system based on spatial configuration of the imaging system, calculating one or more rendering parameters associated with one of the one or more objects in the image frame based on at least the depth information of the one or more objects, and rendering the image frame using the one or more rendering parameters to obtain a processed image frame. The processed image frame includes an in-focus region and an out-of-focus region relative to the one of the one or more objects.