Invention Grant
- Patent Title: Aromatic compound
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Application No.: US16499432Application Date: 2018-03-29
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Publication No.: US11186565B2Publication Date: 2021-11-30
- Inventor: Seiji Miwatashi , Yasufumi Miyamoto , Koji Watanabe , Yayoi Nakayama , Yuko Hitomi , Jumpei Aida , Nobuyuki Takakura , Hideki Furukawa , Naoyoshi Noguchi , Yasuhiro Hirata , Kazuaki Takami , Norihito Tokunaga , Tomohiro Okawa , Akito Shibuya , Shizuo Kasai , Toshitake Kobayashi , Tsuyoshi Maekawa
- Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Applicant Address: JP Osaka
- Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JPJP2017-072811 20170331
- International Application: PCT/JP2018/013514 WO 20180329
- International Announcement: WO2018/181847 WO 20181004
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07C59/72 ; C07D211/22 ; C07D213/64 ; C07D401/10 ; C07D401/14 ; C07D413/10

Abstract:
Provided is a novel aromatic ring compound which may have a GPR40 agonist activity and a GLP-1 secretagogue action. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof may have a GPR40 agonist activity and a GLP-1 secretagogue action, may be useful for the prophylaxis or treatment of cancer, obesity, diabetes, hypertension, hyperlipidemia, cardiac failure, diabetic complications, metabolic syndrome, sarcopenia and the like, and may afford superior efficacy.
Public/Granted literature
- US20200039957A1 AROMATIC COMPOUND Public/Granted day:2020-02-06
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