Invention Grant
- Patent Title: Method comprising contacting tissue with a cross-linkable polyester prepolymer
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Application No.: US17097901Application Date: 2020-11-13
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Publication No.: US11458230B2Publication Date: 2022-10-04
- Inventor: Christopher J. Bettinger , Joost P. Bruggeman , Lino Da Silva Ferreira , Jeffrey M. Karp , Robert S. Langer , Christiaan Nijst , Andreas Zumbuehl , Jason Burdick , Sonia J. Kim
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Pabst Patent Group LLP
- Main IPC: C08G63/685
- IPC: C08G63/685 ; C08J3/24 ; C08K5/00 ; A61L31/06 ; A61L27/18 ; A61L27/38 ; A61L27/58 ; C12N11/096 ; C12N11/087 ; A61K35/12 ; A61K35/48 ; A61K45/06 ; A61L31/14

Abstract:
The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-linked to form the elastic biodegradable polymer. In preferred embodiments, the cross-linking is performed by functionalization of one or more OR groups on the pre-polymer backbone with vinyl, followed by photopolymerization to form the elastic biodegradable polymer composition or material. Preferably, acrylate is used to add one or more vinyls to the backbone of the pre-polymer to form an acrylated pre-polymer. In various embodiments, acrylated pre-polymers are co-polymerized with one or more acrylated co-polymers.
Public/Granted literature
- US20210128794A1 METHOD COMPRISING CONTACTING TISSUE WITH A CROSS-LINKABLE POLYESTER PREPOLYMER Public/Granted day:2021-05-06
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