Invention Grant
- Patent Title: Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
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Application No.: US16903173Application Date: 2020-06-16
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Publication No.: US11492368B2Publication Date: 2022-11-08
- Inventor: Zhijian Chen , Lijun Sun , Jiaxi Wu , Heping Shi , Chuo Chen
- Applicant: The Board of Regents of the University of Texas System
- Applicant Address: US TX Austin
- Assignee: The Board of Regents of the University of Texas System
- Current Assignee: The Board of Regents of the University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Fenwick & West LLP
- Agent Hugo Garrido; Carl A. Morales
- Main IPC: C07H21/02
- IPC: C07H21/02 ; A61K39/39 ; A61K31/7084 ; C12Q1/6876 ; C12Q1/25 ; G01N33/573 ; G01N33/564 ; A61K39/00
Abstract:
Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2′3-cGAMP, 2′2-cGAMP, 3′2′-cGAMP and 3′3′-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
Public/Granted literature
- US20200308216A1 PHARMACEUTICAL TARGETING OF A MAMMALIAN CYCLIC DI-NUCLEOTIDE SIGNALING PATHWAY Public/Granted day:2020-10-01
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