- Patent Title: Engineered guide RNA sequences for in situ detection and sequencing
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Application No.: US16346569Application Date: 2017-11-01
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Publication No.: US11732258B2Publication Date: 2023-08-22
- Inventor: Reza Kalhor , Prashant G. Mali , George M. Church
- Applicant: President and Fellows of Harvard College
- Applicant Address: US MA Cambridge
- Assignee: President and Fellows of Harvard College
- Current Assignee: President and Fellows of Harvard College
- Current Assignee Address: US MA Cambridge
- Agency: Banner & Witcoff, Ltd.
- International Application: PCT/US2017/059549 2017.11.01
- International Announcement: WO2018/085414A 2018.05.11
- Date entered country: 2019-05-01
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/11 ; C12N15/10 ; C12Q1/6853 ; C12N9/22 ; C12N15/113
Abstract:
A functional engineered guide RNA sequence is provided including a spacer sequence and a scaffold sequence, wherein the scaffold sequence includes a primer binding site for reverse transcription.
Public/Granted literature
- US20190264202A1 Engineered Guide RNA Sequences for In Situ Detection and Sequencing Public/Granted day:2019-08-29
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