- 专利标题： Bispecific antigen binding molecules targeting OX40 and FAP
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申请号： US17218948申请日： 2021-03-31
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公开(公告)号： US11780919B2公开(公告)日： 2023-10-10
- 发明人: Maria Amann , Juergen Peter Bachl , Alexander Bujotzek , Carina Cantrill , Harald Duerr , Janine Faigle , Sabine Imhof-Jung , Christian Klein , Thomas Kraft , Estelle Marrer-Berger , Ekkehard Moessner , Laurene Pousse , Petra Rueger , Johannes Sam , Roland Staack , Dietrich Tuerck , Pablo Umana , Joerg Zielonka
- 申请人： Hoffmann-La Roche Inc.
- 申请人地址： US NJ Little Falls
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Little Falls
- 代理商 Lawrence S. Graham
- 优先权： EP 167624 2020.04.01
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; C07K16/28 ; A61P35/00 ; A61K45/06 ; C07K16/30 ; C07K16/46
摘要：
The invention relates to novel bispecific antigen binding molecules, comprising at least two antigen binding domains capable of specific binding to OX40 and a particular antigen binding domain capable of specific binding to Fibroblast Activation Protein (FAP), and to methods of producing these molecules and to methods of using the same.
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