- 专利标题: Cyclic compound/peptide comprising an A-beta13-16 peptide and a linker that is covalently coupled to the n-terminus residue and the c-terminus residue of the A-beta13-16 peptide
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申请号: US17011059申请日: 2020-09-03
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公开(公告)号: US11905318B2公开(公告)日: 2024-02-20
- 发明人: Neil R. Cashman , Steven S. Plotkin
- 申请人: The University of British Columbia
- 申请人地址: CA Vancouver
- 专利权人: The University of British Columbia
- 当前专利权人: The University of British Columbia
- 当前专利权人地址: CA Vancouver
- 代理机构: Bereskin & Parr LLP
- 代理商 Carmela De Luca
- 主分类号: C07K7/00
- IPC分类号: C07K7/00 ; C07K14/00 ; A61K38/00 ; A61K38/08 ; A61K38/10 ; A61K38/12 ; A61K38/17 ; C07K14/47 ; C07K16/18 ; C07K5/103 ; C07K5/117 ; A61K47/64 ; C07K7/06 ; C12N5/10 ; C07K7/64 ; A61P25/28 ; A61K39/00 ; A61K39/39 ; A61K51/10 ; G01N33/68 ; A61K49/18 ; A61K39/395 ; A61K38/07 ; A61K47/68 ; A61K45/00 ; A61K51/08 ; A61K47/69 ; A61K38/05 ; A61K45/06 ; C07K7/08 ; C07K16/00 ; C07K14/435 ; G01N33/50 ; A61L27/22 ; A61L27/34 ; A61L31/10 ; A61L31/16 ; A61L29/08 ; A61L29/16
摘要:
The disclosure pertains to conformational epitopes in A-beta, antibodies thereto and methods of making and using immunogens and antibodies specific thereto.
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