Invention Application
- Patent Title: Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
-
Application No.: US11156364Application Date: 2005-06-17
-
Publication No.: US20060025460A1Publication Date: 2006-02-02
- Inventor: Alfredo Castro , Wei Deng , Kristopher Depew , Michael Foley , Christian Fritz , Asimina Georges Evangelinos , Michael Grogan , Nafeeza Hafeez , Edward Holson , Brian Hopkins , Nii Koney , Tao Liu , David Mann , Lisa Marcaurelle , Daniel Snyder , Dennis Underwood , Andrew Wylie , Lin-Chen Yu , Linping Zhang
- Applicant: Alfredo Castro , Wei Deng , Kristopher Depew , Michael Foley , Christian Fritz , Asimina Georges Evangelinos , Michael Grogan , Nafeeza Hafeez , Edward Holson , Brian Hopkins , Nii Koney , Tao Liu , David Mann , Lisa Marcaurelle , Daniel Snyder , Dennis Underwood , Andrew Wylie , Lin-Chen Yu , Linping Zhang
- Applicant Address: US MA Cambridge
- Assignee: Infinity Pharmaceuticals, Inc.
- Current Assignee: Infinity Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Main IPC: C07D261/02
- IPC: C07D261/02 ; A61K31/42
Abstract:
One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
Public/Granted literature
- US07851637B2 Compounds and methods for inhibiting the interaction of BCL proteins with binding partners Public/Granted day:2010-12-14
Information query
